Publication:
Acute effect of hemodialysis on arterial elasticity

Thumbnail Image

Date

2015-01-01

Authors

Sağ, Saim
Yeşilbursa, Dilek
Yıldız, Abdülmecit
Dilek, Kamil
Şentürk, Tunay
Serdar, Osman Akın
Aydınlar, Ali

Journal Title

Journal ISSN

Volume Title

Publisher

TÜBİTAK

Research Projects

Organizational Units

Journal Issue

Abstract

Background/aim: Reduced arterial elasticity is an independent predictor of cardiovascular mortality in patients with end-stage renal disease (ESRD). Hemodialysis (HD) treatment per se can bring additional risk factors for vascular disease. Our study was designed to determine whether a single hemodialysis session leads to an acute alteration in parameters of arterial elasticity in ESRD.Materials and methods: In this study, 58 patients undergoing chronic hemodialysis and 29 healthy controls were enrolled. Large artery elasticity index (LAEI) and the small artery elasticity index (SAEI) were measured by applanation tonometry. The acute effect of a hemodialysis session on arterial elasticity indices was assessed by comparison of prehemodialysis and posthemodialysis determinations.Results: At baseline, LAEI did not differ significantly in patients compared with controls. In contrast, the SAEI was significantly lower in patients (4.1 +/- 2.6 mL/mmHg x 100) than in healthy individuals (8.9 +/- 3.4 mL/mmHg x 100, P < 0.05). In patients with ESRD, no significant changes in LAEI was observed after HD, but SAEI deteriorated significantly (from 4.1 +/- 2.6 mL/mmHg x 100 to 3.4 +/- 2.3, P < 0.05).Conclusion: We conclude that ESRD patients face a significant reduction in SAEI, which is exacerbated by a dialysis procedure.

Description

Keywords

Cardiovascular-disease, Endothelial function, Stiffness, Predicts, Therapy, Death, Arterial elasticity, Hemodialysis, Applanation tonometry, General & internal medicine

Citation

Collections

1

Views

5

Downloads

Search on Google Scholar