Person: SERDAR, OSMAN AKIN
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SERDAR
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OSMAN AKIN
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Publication Coronary risk factors and coronary angiography results of 12.201 patients(Elsevier, 2015-07-01) Günay, Şeyda; Serdar, Osman Akın; Özyılmaz, Sinem; Dereli, Seçkin; Aydınlar, Ali; Baran, İbrahim; Özdemir, Burhan; Yeşilbursa, Dilek; Güllülü, Sumeyye; Kaderli, Aysel Aydın; Şentürk, Tunay; GÜNAY POLATKAN, ŞEYDA; SERDAR, OSMAN AKIN; Özyılmaz, Sinem; Dereli, Seçkin; AYDINLAR, ALİ; Baran, İbrahim; Özdemir, Burhan; YEŞİLBURSA, DİLEK; GÜLLÜLÜ, NAZMİYE SÜMEYYE; Kaderli, Aysel Aydın; ŞENTÜRK, TUNAY; Uludağ Üniversitesi; 0000-0003-1744-8883; 0000-0003-0090-3835; 0000-0002-8974-8837; 0000-0003-4829-8400; 0000-0003-0012-345X; AAI-5350-2021; AAI-6632-2021; AAG-8709-2020; AAB-5861-2021; AAJ-3962-2020; C-1517-2017; AAF-5116-2019; CDA-1396-2022; FRF-3343-2022Publication Acute effect of hemodialysis on arterial elasticity(TÜBİTAK, 2015-01-01) Sağ, Saim; Yeşilbursa, Dilek; Yıldız, Abdülmecit; Dilek, Kamil; Şentürk, Tunay; Serdar, Osman Akın; Aydınlar, Ali; Sağ, Saim; YEŞİLBURSA, DİLEK; YILDIZ, ABDULMECİT; DİLEK, KAMİL; ŞENTÜRK, TUNAY; SERDAR, OSMAN AKIN; AYDINLAR, ALİ; Uludağ Üniversitesi/Tıp Fakültesi/Kardiyoloji Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Nefroloji Anabilim Dalı.; 0000-0003-1744-8883; 0000-0001-8404-8252; AAW-9185-2020; C-1517-2017; AAF-5116-2019; AAI-6632-2021; EHA-0046-2022; HIG-9032-2022; EUF-5229-2022Background/aim: Reduced arterial elasticity is an independent predictor of cardiovascular mortality in patients with end-stage renal disease (ESRD). Hemodialysis (HD) treatment per se can bring additional risk factors for vascular disease. Our study was designed to determine whether a single hemodialysis session leads to an acute alteration in parameters of arterial elasticity in ESRD.Materials and methods: In this study, 58 patients undergoing chronic hemodialysis and 29 healthy controls were enrolled. Large artery elasticity index (LAEI) and the small artery elasticity index (SAEI) were measured by applanation tonometry. The acute effect of a hemodialysis session on arterial elasticity indices was assessed by comparison of prehemodialysis and posthemodialysis determinations.Results: At baseline, LAEI did not differ significantly in patients compared with controls. In contrast, the SAEI was significantly lower in patients (4.1 +/- 2.6 mL/mmHg x 100) than in healthy individuals (8.9 +/- 3.4 mL/mmHg x 100, P < 0.05). In patients with ESRD, no significant changes in LAEI was observed after HD, but SAEI deteriorated significantly (from 4.1 +/- 2.6 mL/mmHg x 100 to 3.4 +/- 2.3, P < 0.05).Conclusion: We conclude that ESRD patients face a significant reduction in SAEI, which is exacerbated by a dialysis procedure.Publication Association between arterial stiffness and acute exacerbations in patients with chronic obstructive pulmonary disease(European Respiratory Soc Journals Ltd, 2015-09-01) Özyılmaz, Sinem Özbay; Özyılmaz, İsa; Serdar, Osman Akın; Uzaslan, Esra; Özyılmaz, Sinem Özbay; SERDAR, OSMAN AKIN; UZASLAN, AYŞE ESRA; Uludağ Üniversitesi/Tıp Fakültesi/Kardiyoloji Anabilim Dalı; Uludağ Üniversitesi/Tıp Fakültesi/Göğüs Hastalıkları Anabilim Dalı; 0000-0003-1744-8883; AAJ-3962-2020; AAF-5116-2019; AAI-1004-2021; AAG-8709-2020Publication Arterial elasticity measurement in patients with Behcet's disease(Elsevier Science Inc, 2013-10-29) Uçar, Hakan; Karaağaç, Kemal; Aktürk, Yusuf; Serdar, Osman Akin; SERDAR, OSMAN AKIN; Saricaoglu, Hayriye; SARICAOĞLU, HAYRİYE; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Kardiyoloji Anabilim Dalı.; 0000-0003-1744-8883; AAF-5116-2019Publication Coronary risk factors and coronary angiography results of 12.257 patients(Elsevier, 2013-10-29) Günay, Şeyda; Serdar, Osman Akın; Özyılmaz, Sinem Özbay; Dereli, Seçkin; Aydınlar, Ali; Baran, İbrahim; Özdemir, Bülent; Yeşilbursa, Dilek; Güllülü, Sümeyye; GÜNAY POLATKAN, ŞEYDA; SERDAR, OSMAN AKIN; Özyılmaz, Sinem Özbay; Dereli, Seçkin; AYDINLAR, ALİ; Baran, İbrahim; ÖZDEMİR, BÜLENT; YEŞİLBURSA, DİLEK; GÜLLÜLÜ, NAZMİYE SÜMEYYE; Uludağ Üniversitesi/Tıp Fakültesi/Kardiyoloji Anabilim Dalı; 0000-0003-1744-8883; 0000-0002-7788-9739; 0000-0003-0090-3835; AAF-5116-2019; AAG-8709-2020; AAI-5350-2021; AAI-6632-2021; AAJ-3962-2020; AAB-5861-2021; CDA-1396-2022; JHE-3353-2023; EHA-0046-2022; JGR-6552-2023Publication Working at night in hospital environment is a risk factor for arterial stiffness(Galenos Yayıncılık, 2012-09-01) Özbay, Sinem; Özyılmaz, İsa; Uysal, Ali; Hamidi, Mehmet; Serdar, Osman Akın; Özbay, Sinem; Uysal, Ali; Hamidi, Mehmet; SERDAR, OSMAN AKIN; Uludağ Üniversitesi/Tıp Fakültesi/Kardioloji Anabilim Dalı.; 0000-0003-1744-8883; AAF-5116-2019; JRP-4699-2023; GGS-7280-2022; CUK-5425-2022Aim: Arterial stiffness is an independent risk factor for cardiovascular disease. In previous studies, emotional stress has been reported to be a risk factor for cardiovascular disease. In this study, we aimed to investigate the effects of anxiety, stress and fatigue associated with working at night in hospital environment on arterial stiffness in physicians.Methods: The study was carried out with 30 physicians employed in Medical Faculty of Uludag University between October 2011 and March 2012. Measurements were made using Pulse Wave Sensor HDI system (Hypertension Diagnostics Inc, Eagan, MN)(Set No: CR000344) by radial artery pulse wave at the onset and end of night shift.Results: The mean age of night doctors included in the study was 26 years (range: 22-38) and the female/male ratio was 2/1. It was determined that mean values of arterial stiffness were significantly higher after night shift (1330 +/- 360 dyne/sn/cm-5) compared to mean values before night shift (1093 +/- 250 dyn/s/cm-5) (p=0.01). In the evaluation of other parameters before and after night shift, no statistically significant difference was detected (p>0.05).Conclusion: The increasing arterial stiffness in hospital employees after night shift could be attributed to the effects of stress and fatigue experienced during night shift.Publication Dislodgement of a sirolimus-eluting stent in the circumflex artery and its successful deployment with a small-balloon technique(Turkish Soc Cardiology, 2011-07-01) Şentürk, Tunay; YEŞİLBURSA, DİLEK; ŞENTÜRK, TUNAY; ÖZDEMİR, BÜLENT; Özdemir, Bülent; Serdar, Osman Akın; SERDAR, OSMAN AKIN; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Kardiyoloji Anabilim Dalı.; 0000-0003-1744-8883; AAF-5116-2019; C-1517-2017Coronary stent dislodgement or embolization before deployment is a rare but serious complication in interventional cardiology. A 60-year-old male presented with unstable angina five years after coronary artery bypass surgery. There was a stenosis (70%) in the obtuse marginal branch of the circumflex artery. During percutaneous coronary intervention, a sirolimus-eluting stent was stripped from its balloon mainly because of significant proximal angulation and incarcerated within the proximal circumflex artery. A smaller balloon dilatation catheter was advanced and pushed through the inside of the slipped stent. Using this technique, the stent could be advanced into the lesion and was successfully deployed. To our knowledge, this is the first case report on sirolimus-eluting stent dislodgement.Publication The relationship of acute exacerbation severity with uric acid and uric acid to creatinine ratio in patients with chronic obstructive pulmonary disease(Galenos Yayincilik, 2013-12-01) Özyılmaz, İsa; Özyılmaz, Sinem Ozbay; Serdar, Osman Akın; SERDAR, OSMAN AKIN; Uzaslan, Esra; UZASLAN, AYŞE ESRA; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Kardiyoloji Anabilim Dalı.; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Göğüs Hastalıkları Anabilim Dalı.; 0000-0003-1744-8883; AAJ-3962-2020; AAG-8709-2020; AAF-5116-2019Aim: Acute exacerbation in chronic obstructive pulmonary disease (COPD) may result in a lot of systemic consequences due to hypoxemia and systemic inflammation. We investigated uric acid levels and uric acid to creatinine ratio in COPD patients developing acute exacerbation.Methods: We included 25 patients who had been admitted with acute exacerbation of COPD according to the GOLD diagnosis and treatment guidelines between May and December 2011. Uric acid and creatinine levels were recorded from blood samples of the patients.Results: Average uric acid and uric acid to creatinine ratio values were 5.7 +/- 2.09 mg/dl and 7.32 +/- 3.0 in patients with mild hypoxemia, 6.4 +/- 2.1 mg/dl and 7.01 +/- 2.9 in those with moderate hypoxemia, and 6.7 +/- 2.0 mg/dl and 9.1 +/- 1.8 in those with severe hypoxemia, respectively. While no statistically significant correlation was found between uric acid levels and uric acid to creatinine ratio in the three groups (p=0.97, p=0.76, respectively), these values were found to increase along with increasing severity of hypoxemia.Conclusion: Uric acid levels and the ratio of uric acid to creatinine remained unchanged while severity of hypoxemia increased during acute exacerbations of COPD, however, these values were found to increase with increasing severity of hypoxemia.Publication Comparison of pneumatic compression device and sand bag with respect to peripheral vascular complications in elective cardiac catheterization and percutaneous femoral artery interventions(Turkish Soc Cardiology, 2013-09-01) Besli, Feyzullah; Alışır, Mehmet Fethi; Keçebaş, Mesut; Serdar, Osman Akin; SERDAR, OSMAN AKIN; Güngören, Fatih; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Kardiyoloji Anabilim Dalı.; 0000-0002-6206-8700; 0000-0003-1744-8883; AAF-5116-2019; AAA-3163-2021Objectives: After coronary angiography (CAG) and percutaneous coronary intervention (PCI), the classic sand bag method and compression devices are widely used for control of bleeding and prevention of vascular complications on the intervention site. The purpose of our study was to assess the major peripheral vascular complications and compare the sand bag and a pneumatic compression device ("Close Pad") in terms of major peripheral vascular complications occurring after CAG, and PCI.Study design: Between June 2011 and November 2011, a total of 434 patients who were admitted to the Department of Cardiology of Uludag University Faculty of Medicine were included in the study. 396 patients underwent coronary angiography and 38 patients, PCI. Sand bag, and Close Pad were applied in 209, and 225 patients, respectively. Bleeding requiring transfusion, hematomas larger than 10 cm(2), pseudoaneurysm, and arteriovenous (AV) fistula were defined as the major local complications. Logistic regression analysis were used to evaluate the data.Results: Major vascular complications occurred in 2% of diagnostic angiography and in 13.2% of PCIs (p=0.003). The major vascular complications were significantly higher with the Close Pad device compared with sand bag (5.3% vs. 0.5%, p=0.007). Smoking, PCI, Close Pad application, use of clopidogrel, and anticoagulants were observed to have increased risk for major local complications. In the logistic regression analysis, only smoking and Close Pad usage were evaluated as independent variables that increased the risk of major vascular complications (p<0.05).Conclusion: Close Pad usage increases risk of vascular complications when compared with the sand bag in patients undergoing cardiac catheterizations. Especially after PCI, patients who will use Close Pad should be selected carefully