Publication: Successful treatment of central nervous system involvement in posttransplant EBV-related lymphoproliferative disease with intrathecal rituximab therapy
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Authors
Aslan, Fatma
Güler, Salih
Evim, Melike Sezgin
Aslıer, Mustafa
Yazıcı, Zeynep
Nazlıoğlu, Hülya Öztürk
Güneş, Adalet Meral
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Lippincott Williams & Wilkins
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Abstract
The posttransplant lymphoproliferative disease is a severe cause of morbidity and mortality following allogeneic hematopoietic stem cell transplantation. Central Nervous System involvement in EBV-related PTLD is rare, and there is no standard treatment recommendation. We present our patient and discuss other previously reported cases of EBV-associated PTLD with CNS involvement.
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Keywords
Stem-cell transplantation, Cns, Cns involvement, Ptld, Hsct, Intrathecal rituximab, Oncology, Hematology, Pediatrics