A phylogenetic and genotyping study of bovine herpesvirus type 4 (bhv-4) in Turkey

dc.contributor.authorKoç, Taylan
dc.date.accessioned2020-12-22T11:48:42Z
dc.date.available2020-12-22T11:48:42Z
dc.date.issued2020-05-26
dc.description.abstractInfertility and reproductive infections are the huge problems for the diary management throughout the world. Bovine herpesviruses act an enormous role in these complicated problems. Bovine Herpesvirus Type 1 (BHV-1) is the most outstanding herpesvirus causing genital and uterine tracts infections among other reproductive viral agents, however, Bovine Herpesvirus Type 4 (BHV-4) is also responsible in terms of similar symptoms and diseases. The main aims of the study are both to investigate the underlying potential presence of BHV-4 in subclinical uterine tract infection, and both to perform molecular and recombination analyses. A herd including 25 repeat breeder cows were investi-gated by BHV-4. Two out of them were determined BHV-4 infected after a series of Polymerase Chain Reactions (PCRs) tests which able to amplify partial Glycoprotein B (gB) and Thymidine Kinase (TK) gene regions. Obtained sequences were analyzed by using phylogenetic and recombinational software, and two Maximum Likelihood (ML) tree have been constructed. To results, novel Turkish BHV-4 sequences fell into Genotype I in both constructed Maximum Likelihood (ML) phylogenetic trees, however, no recombination evidence has been observed in relevant software. This report is one of the rare genotyping studies on BHV-4 from Turkey. This study showed that Turkish BHV-4 strains, as molecular, were highly probable to originate from European strains and might be observed in different clinical reflections. This suggests that BHV-4 should be deeply investigated by further molecular techniques and included in diagnostic panels for reproductive viruses.en_US
dc.identifier.citationKoç, B. T. (2020). "A phylogenetic and genotyping study of bovine herpesvirus type 4 (bhv-4) in Turkey". Bursa Uludağ Üniversitesi Veteriner Fakültesi, 39(1), 61-66.tr_TR
dc.identifier.endpage66tr_TR
dc.identifier.issn1301-3173
dc.identifier.issue1tr_TR
dc.identifier.startpage61tr_TR
dc.identifier.urihttps://dergipark.org.tr/tr/download/article-file/1221222
dc.identifier.urihttp://hdl.handle.net/11452/14561
dc.identifier.volume39tr_TR
dc.language.isoenen_US
dc.publisherBursa Uludağ Üniversitesitr_TR
dc.relation.journalVeteriner Hekimlikte Araştırma Dergisi / Journal of Research in Veterinary Medicinetr_TR
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectReproductive infectionen_US
dc.subjectBovine herpesvirus type 4 (BHV-4)en_US
dc.subjectRepeat-breederen_US
dc.subjectInfertilityen_US
dc.subjectGenotypingen_US
dc.subjectTurkeyen_US
dc.titleA phylogenetic and genotyping study of bovine herpesvirus type 4 (bhv-4) in Turkeyen_US
dc.typeArticleen_US

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