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Title: Arterial lesions in Behcet's disease
Authors: Uludağ Üniversitesi/Tıp Fakültesi/Göğüs Cerrahisi Anabilim Dalı.
Uludağ Üniversitesi/Tıp Fakültesi/Dermatoloji Anabilim Dalı.
Uludağ Üniversitesi/Tıp Fakültesi/Radyoloji Anabilim Dalı.
Uludağ Üniversitesi/Tıp Fakültesi/Romatoloji Anabilim Dalı.
Uludağ Üniversitesi/Tıp Fakültesi/Kalp Damar Cerrahisi Anabilim Dalı.
Saba, Davit
Sarıcaoğlu, Hayriye
Bayram, Ahmet Sami
Erdoğan, Cüneyt
Dilek, Kamil
Gebitekin, Cengiz
Özkan, Hayati
Özer, Z. Gökalp
Keywords: Cardiovascular system & cardiology
Behcet's disease
Arterial lesions
Pulmonary artery aneurysm
Vascular involvement
Pulmonary manifestations
Issue Date: May-2003
Publisher: Verlag Hans Huber
Citation: Saba, D. vd. (2003). “Arterial lesions in Behcet's disease”. Vasa-Journal of Vascular Diseases, 32(2), 75-81.
Abstract: Background: Arterial involvement is a rare but serious condition in the course of Behcet's disease. We aimed to assess the results of therapeutic approaches in our patients with arterial lesions caused by Behcet's disease. Patients and methods: The records of 534 patients with Behcet's disease between 1987 and 2002 were retrospectively evaluated for the presence of arterial lesions. All patients were followed up regularly, at 3 to 6 months intervals. Results: Arterial lesions were diagnosed in 21 (3.9%) patients. Eight of these patients had pulmonary artery aneurysms (PAA), and the other 13 patients had non-pulmonary arterial lesions. Urgent surgical intervention was performed in three patients with PAA leading to death in all three. In addition, three other patients died due to massive haemoptysis at home despite to immunosuppressive therapy. Only two out of eight patients with PAA are still alive who were treated with cyclophophamide and corticosteroids. Thirteen operations were performed in 7 out of 13 patients having non-puhnonary arterial lesions. Although ten of the operations were primary operations, three reoperations had to be performed. A stent-graft was applied for the management of an iliac artery aneurysm in one patient. Only one patient died 8 years after the first non-pulmonary arterial involvement following a type IV thoracoabdominal aortic aneurysm repair Five patients with arterial occlusive lesions were successfully treated by corticosteroids. Conclusions: Pulmonary artery aneurysms in Behcet's disease patients have a poor prognosis despite any form of therapy. High dose corticosteroids alone can be successfully used for isolated non-pulmonary arterial occlusive lesions, unless disabling symptoms occur. Surgery or stent-graft insertion is indicated,for non-pulmonary arterial aneurysms because these aneurysms entail high risk of complications.
ISSN: 0301-1526
Appears in Collections:Scopus
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