Publication:
Arterial lesions in Behcet's disease

dc.contributor.buuauthorSaba, Davit
dc.contributor.buuauthorSarıcaoğlu, Hayriye
dc.contributor.buuauthorBayram, Ahmet Sami
dc.contributor.buuauthorErdoğan, Cüneyt
dc.contributor.buuauthorDilek, Kamil
dc.contributor.buuauthorGebitekin, Cengiz
dc.contributor.buuauthorÖzkan, Hayati
dc.contributor.buuauthorÖzer, Z. Gökalp
dc.contributor.departmentTıp Fakültesi
dc.contributor.departmentTıp Fakültesi
dc.contributor.departmentTıp Fakültesi
dc.contributor.departmentTıp Fakültesi
dc.contributor.departmentTıp Fakültesi
dc.contributor.departmentRomatoloji Ana Bilim Dalı
dc.contributor.departmentGöğüs Cerrahisi Ana Bilim Dalı
dc.contributor.departmentDermatoloji Ana Bilim Dalı
dc.contributor.departmentRadyoloji Ana Bilim Dalı
dc.contributor.departmentKalp Damar Cerrahisi Ana Bilim Dalı
dc.contributor.researcheridABB-7580-2020
dc.contributor.scopusid55987378200
dc.contributor.scopusid6603722836
dc.contributor.scopusid8347194000
dc.contributor.scopusid8293835700
dc.contributor.scopusid56005080200
dc.contributor.scopusid6602156436
dc.contributor.scopusid7103355993
dc.contributor.scopusid6701509634
dc.date.accessioned2021-09-08T08:53:15Z
dc.date.available2021-09-08T08:53:15Z
dc.date.issued2003-05
dc.description.abstractBackground: Arterial involvement is a rare but serious condition in the course of Behcet's disease. We aimed to assess the results of therapeutic approaches in our patients with arterial lesions caused by Behcet's disease. Patients and methods: The records of 534 patients with Behcet's disease between 1987 and 2002 were retrospectively evaluated for the presence of arterial lesions. All patients were followed up regularly, at 3 to 6 months intervals. Results: Arterial lesions were diagnosed in 21 (3.9%) patients. Eight of these patients had pulmonary artery aneurysms (PAA), and the other 13 patients had non-pulmonary arterial lesions. Urgent surgical intervention was performed in three patients with PAA leading to death in all three. In addition, three other patients died due to massive haemoptysis at home despite to immunosuppressive therapy. Only two out of eight patients with PAA are still alive who were treated with cyclophophamide and corticosteroids. Thirteen operations were performed in 7 out of 13 patients having non-puhnonary arterial lesions. Although ten of the operations were primary operations, three reoperations had to be performed. A stent-graft was applied for the management of an iliac artery aneurysm in one patient. Only one patient died 8 years after the first non-pulmonary arterial involvement following a type IV thoracoabdominal aortic aneurysm repair Five patients with arterial occlusive lesions were successfully treated by corticosteroids. Conclusions: Pulmonary artery aneurysms in Behcet's disease patients have a poor prognosis despite any form of therapy. High dose corticosteroids alone can be successfully used for isolated non-pulmonary arterial occlusive lesions, unless disabling symptoms occur. Surgery or stent-graft insertion is indicated,for non-pulmonary arterial aneurysms because these aneurysms entail high risk of complications.
dc.identifier.citationSaba, D. vd. (2003). “Arterial lesions in Behcet's disease”. Vasa-Journal of Vascular Diseases, 32(2), 75-81.
dc.identifier.endpage81
dc.identifier.issn0301-1526
dc.identifier.issue2
dc.identifier.pubmed12945099
dc.identifier.scopus2-s2.0-0037524304
dc.identifier.startpage75
dc.identifier.urihttps://doi.org/10.1024/0301-1526.32.2.75
dc.identifier.urihttps://econtent.hogrefe.com/doi/10.1024/0301-1526.32.2.75
dc.identifier.urihttp://hdl.handle.net/11452/21765
dc.identifier.volume32
dc.identifier.wos000183487300004
dc.indexed.wosSCIE
dc.language.isoen
dc.publisherVerlag Hans Huber
dc.relation.journalVasa - Journal of Vascular Diseases
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectCardiovascular system & cardiology
dc.subjectBehcet's disease
dc.subjectArterial lesions
dc.subjectPulmonary artery aneurysm
dc.subjectVascular involvement
dc.subjectPulmonary manifestations
dc.subjectAneurysms
dc.subjectManagement
dc.subjectDiagnosis
dc.subject.emtreeAzathioprine
dc.subject.emtreeCorticosteroid
dc.subject.emtreeCyclophosphamide
dc.subject.emtreeImmunosuppressive agent
dc.subject.emtreePrednisolone
dc.subject.emtreeAbdominal aorta aneurysm
dc.subject.emtreeAdult
dc.subject.emtreeArtery disease
dc.subject.emtreeArtery occlusion
dc.subject.emtreeBehcet disease
dc.subject.emtreeBlood vessel graft
dc.subject.emtreeCause of death
dc.subject.emtreeControlled study
dc.subject.emtreeCorticosteroid therapy
dc.subject.emtreeDisease severity
dc.subject.emtreeFollow up
dc.subject.emtreeHemoptysis
dc.subject.emtreeHuman
dc.subject.emtreeImmunosuppressive treatment
dc.subject.emtreeLobectomy
dc.subject.emtreeMajor clinical study
dc.subject.emtreePrognosis
dc.subject.emtreePulmonary artery aneurysm
dc.subject.emtreeReoperation
dc.subject.emtreeStent
dc.subject.emtreeTreatment outcome
dc.subject.scopusBehcet syndrome; False aneurysm; Systemic vasculitis
dc.subject.wosPeripheral vascular disease
dc.titleArterial lesions in Behcet's disease
dc.typeArticle
dspace.entity.typePublication
local.contributor.departmentTıp Fakültesi/Göğüs Cerrahisi Ana Bilim Dalı
local.contributor.departmentTıp Fakültesi/Dermatoloji Ana Bilim Dalı
local.contributor.departmentTıp Fakültesi/Radyoloji Ana Bilim Dalı
local.contributor.departmentTıp Fakültesi/Romatoloji Ana Bilim Dalı
local.contributor.departmentTıp Fakültesi/Kalp Damar Cerrahisi Ana Bilim Dalı
local.indexed.atScopus
local.indexed.atWOS

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