Investigation of a natural pH-indicator dye for nanofibrous wound dressings

Abstract

In this study, fast responding and user-friendly biocompatible, halochromic nanofibrous mat was successfully produced for the purpose of wound healing monitoring, including a natural pH-indicator dye which was extracted from Red cabbage (B. oleracea L.) inside an alginate (NaAlg) and polyvinyl alcohol (PVA) mixture solution. The morphological characterization of the halochromic nanofibrous mat was examined by scanning electron microscope. Nanofibrous mats exhibited a pink color when exposed to pH 4-6, simulating the wound-milieu salubrious to the wound healing, and a green-blue color when exposed to pH 7-10, simulating the wound-milieu that obstacle wound healing.