Goodpasture's syndrome initially presenting with alveolar hemorrhage

Abstract

Goodpasture's syndrome is characterized by rapidly progresive glomerulonephritis, presence of deposited and circulating anti-glomerular basement membrane (GBM) antibodies which often accompanied by lung haemorrhage. The antigen target in Goodpasture's syndrome is the alpha 3 chain of type IV collagen. Heamoptysis may be the initial symptom. We present a case of Goodpasture's syndrome presented with diffuse alveolar heamorrhage.