Publication:
The connection between hormones and antiepileptic drugs

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dc.contributor.buuauthorBora, İbrahim
dc.contributor.buuauthorBORA, İBRAHİM HAKKI
dc.contributor.departmentTıp Fakültesi
dc.contributor.departmentNöroloji Ana Bilim Dalı
dc.date.accessioned2024-10-10T12:37:06Z
dc.date.available2024-10-10T12:37:06Z
dc.date.issued2018-01-01
dc.description.abstractEpilepsy and antiepileptic medicine (EAM) has an effect on hormonal and neuroendocrine system and also it there is complex connection between these and reproduction system. Hormonal and neuro endocrine changes may cause a shift in seizure threshold and may result in comorbid diseases like, sexual and reproductive problems, deterioration in thyroid functions and obesity. Sexual dysfunctioning is a critical side effect on quality of life and it is a crucial health indicator for males with epileptic history. Endocrine dysfunctioning related to reproductively are observed more in women with epilepsy compared to healthy population. 30% of women with epilepsy have reproduction related functional deterioration. Both epileptic discharges and EAM usage result in deterioration in central and peripheral control of hypothalamic pituitary gonadal axis and as a result start of a treatment and follow up process gains importance for epileptic patients.
dc.identifier.doi10.14744/epilepsi.2018.93898
dc.identifier.endpage59
dc.identifier.issn1300-7157
dc.identifier.issueSupplement 1
dc.identifier.startpage51
dc.identifier.urihttps://doi.org/10.14744/epilepsi.2018.93898
dc.identifier.urihttps://hdl.handle.net/11452/46218
dc.identifier.volume24
dc.identifier.wos000438304900010
dc.indexed.wosWOS.ESCI
dc.language.isoen
dc.publisherKare Publ
dc.relation.journalEpilepsi
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectReproductive endocrine function
dc.subjectSexual dysfunction
dc.subjectEpilepsy
dc.subjectWomen
dc.subjectMen
dc.subjectCarbamazepine
dc.subjectValproate
dc.subjectOxcarbazepine
dc.subjectTopiramate
dc.subjectHealth
dc.subjectAntiepileptic drug
dc.subjectHormone
dc.subjectNeuroendocrine system
dc.subjectScience & technology
dc.subjectLife sciences & biomedicine
dc.subjectClinical neurology
dc.subjectNeurosciences & neurology
dc.titleThe connection between hormones and antiepileptic drugs
dc.typeReview
dspace.entity.typePublication
local.contributor.departmentTıp Fakültesi/Nöroloji Ana Bilim Dalı
local.indexed.atWOS
relation.isAuthorOfPublication7674bbf4-9c63-42a4-b1e0-09ecdcb8f05a
relation.isAuthorOfPublication.latestForDiscovery7674bbf4-9c63-42a4-b1e0-09ecdcb8f05a

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