Enantioselective synthesis of 2-amino-4-(nitromethyl)-4H-chromene-3-carbonitriles from 2-iminochromenes

Koz, Gamze; Koz, Ömer

Publication:
Enantioselective synthesis of 2-amino-4-(nitromethyl)-4H-chromene-3-carbonitriles from 2-iminochromenes

dc.contributor.author	Koz, Gamze
dc.contributor.author	Koz, Ömer
dc.contributor.buuauthor	Coşkun, Necdet
dc.contributor.department	Fen Edebiyat Fakültesi
dc.contributor.department	Kimya Bölümü
dc.contributor.researcherid	B-1200-2012
dc.contributor.scopusid	7004177880
dc.date.accessioned	2022-12-19T13:17:27Z
dc.date.available	2022-12-19T13:17:27Z
dc.date.issued	2016-04-22
dc.description.abstract	A series of medicinally important 2-amino-4-(nitromethyl)-4H-chromene-3-carbonitriles were synthesized using enantioselective conjugate addition of nitromethane to 2-iminochromenes. The reactions were performed using L8-Cu (II) catalytic system and moderate to good enantioselectivities (62-88%) and yields (66-96%) were obtained.
dc.identifier.citation	Koz, G. vd. (2016). "Enantioselective synthesis of 2-amino-4-(nitromethyl)-4H-chromene-3-carbonitriles from 2-iminochromenes". Synthetic Communications, 46(10), 909-915.
dc.identifier.endpage	915
dc.identifier.issn	0039-7911
dc.identifier.issn	1532-2432
dc.identifier.issue	10
dc.identifier.scopus	2-s2.0-84973129536
dc.identifier.startpage	909
dc.identifier.uri	https://doi.org/10.1080/00397911.2016.1177728
dc.identifier.uri	https://www.tandfonline.com/doi/full/10.1080/00397911.2016.1177728
dc.identifier.uri	http://hdl.handle.net/11452/29963
dc.identifier.volume	46
dc.identifier.wos	000378147800007
dc.indexed.wos	SCIE
dc.indexed.wos	IC
dc.indexed.wos	CCRE
dc.language.iso	en
dc.publisher	Taylor & Francis
dc.relation.collaboration	Yurt içi
dc.relation.journal	Synthetic Communications
dc.relation.publicationcategory	Makale - Uluslararası Hakemli Dergi
dc.relation.tubitak	BIDEB 2218
dc.rights	info:eu-repo/semantics/closedAccess
dc.subject	Chemistry
dc.subject	Amino alcohol catalyst
dc.subject	Enantioselective conjugate addition
dc.subject	2-iminochromene
dc.subject	Nitromethane
dc.subject	Asymmetric conjugate addition
dc.subject	Michael addition
dc.subject	Privileged structures
dc.subject	Efficient
dc.subject	Derivatives
dc.subject	Nitroalkanes
dc.subject	Apoptosis
dc.subject	Chromene
dc.subject	Salicylaldehydes
dc.subject	Malononitrile
dc.subject.emtree	Amine
dc.subject.emtree	Chromene derivative
dc.subject.emtree	Copper
dc.subject.emtree	Cyanide
dc.subject.emtree	Imine
dc.subject.emtree	Nitro derivative
dc.subject.emtree	Nitromethane
dc.subject.emtree	Article
dc.subject.emtree	Catalysis
dc.subject.emtree	Catalyst
dc.subject.emtree	Conjugation
dc.subject.emtree	Enantioselectivity
dc.subject.emtree	Quantum yield
dc.subject.emtree	Reaction analysis
dc.subject.emtree	Synthesis
dc.subject.scopus	Dihydropyrano(2,3-C)Pyrazole; Catalyst; Benzopyrans
dc.subject.wos	Chemistry, organic
dc.title	Enantioselective synthesis of 2-amino-4-(nitromethyl)-4H-chromene-3-carbonitriles from 2-iminochromenes
dc.type	Article
dc.wos.quartile	Q3
dspace.entity.type	Publication
local.contributor.department	Fen Edebiyat Fakültesi/Kimya Bölümü
local.indexed.at	Scopus
local.indexed.at	WOS