Yayın: Enantioselective synthesis of 2-amino-4-(nitromethyl)-4H-chromene-3-carbonitriles from 2-iminochromenes
Tarih
Kurum Yazarları
Coşkun, Necdet
Yazarlar
Koz, Gamze
Koz, Ömer
Danışman
Dil
Türü
Yayıncı:
Taylor & Francis
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Özet
A series of medicinally important 2-amino-4-(nitromethyl)-4H-chromene-3-carbonitriles were synthesized using enantioselective conjugate addition of nitromethane to 2-iminochromenes. The reactions were performed using L8-Cu (II) catalytic system and moderate to good enantioselectivities (62-88%) and yields (66-96%) were obtained.
Açıklama
Kaynak:
Anahtar Kelimeler:
Konusu
Chemistry, Amino alcohol catalyst, Enantioselective conjugate addition, 2-iminochromene, Nitromethane, Asymmetric conjugate addition, Michael addition, Privileged structures, Efficient, Derivatives, Nitroalkanes, Apoptosis, Chromene, Salicylaldehydes, Malononitrile
Alıntı
Koz, G. vd. (2016). "Enantioselective synthesis of 2-amino-4-(nitromethyl)-4H-chromene-3-carbonitriles from 2-iminochromenes". Synthetic Communications, 46(10), 909-915.