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Semisynthesis and pharmacological activities of tetrac analogs: Angiogenesis modulators

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dc.contributor.authorBridoux, Alexandre
dc.contributor.authorCui, Huadong
dc.contributor.authorDyskin, Evgeny A.
dc.contributor.authorMousa, Shaker A.
dc.contributor.buuauthorYalçın, Murat
dc.contributor.departmentVeteriner Fakültesi
dc.contributor.departmentFizyoloji Ana Bilim Dalı
dc.contributor.orcid0000-0002-5600-8162
dc.contributor.researcheridAAG-6956-2021
dc.contributor.scopusid57192959734
dc.date.accessioned2021-12-10T08:12:08Z
dc.date.available2021-12-10T08:12:08Z
dc.date.issued2009-06-15
dc.description.abstractNovel Tetrac analogs were synthesized and then tested. Anti-angiogenesis efficacy was carried out using the Chick Chorioallantoic Membrane (CAM) model and the mouse matrigel model for angiogenesis. Pharmacological activities showed Tetrac can accommodate numerous modifications and maintain anti-angiogenesis activity.
dc.identifier.citationBridoux, A. vd. (2009). "Semisynthesis and pharmacological activities of tetrac analogs: Angiogenesis modulators". Bioorganic and Medicinal Chemistry Letters, 19(12), 3259-3263.
dc.identifier.endpage3263
dc.identifier.issn0960-894X
dc.identifier.issue12
dc.identifier.pubmed19427201
dc.identifier.scopus2-s2.0-65749099626
dc.identifier.startpage3259
dc.identifier.urihttps://doi.org/10.1016/j.bmcl.2009.04.094
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S0960894X09006040
dc.identifier.urihttp://hdl.handle.net/11452/23162
dc.identifier.volume19
dc.identifier.wos000266402000024
dc.indexed.wosSCIE
dc.language.isoen
dc.publisherPergamon-Elsevier Science
dc.relation.collaborationYurt dışı
dc.relation.journalBioorganic and Medicinal Chemistry Letters
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectAngiogenesis
dc.subjectEsterification
dc.subjectHPLC
dc.subjectNanopharmaceutical technology
dc.subjectSilylation
dc.subjectTetrac
dc.subjectIntegrin alpha-v-beta-3
dc.subjectExtracellular segment
dc.subjectCrystal-structure
dc.subjectTriiodothyronine
dc.subjectThyroxine
dc.subjectLigand
dc.subjectAcid
dc.subjectPharmacology & pharmacy
dc.subjectChemistry
dc.subject.emtreeAngiogenesis inhibitor
dc.subject.emtreeFibroblast growth factor
dc.subject.emtreeIodine derivative
dc.subject.emtreePhenol derivative
dc.subject.emtreeAngiogenesis
dc.subject.emtreeAnimal experiment
dc.subject.emtreeAntiangiogenic activity
dc.subject.emtreeArticle
dc.subject.emtreeChick embryo
dc.subject.emtreeChorioallantois
dc.subject.emtreeControlled study
dc.subject.emtreeDrug efficacy
dc.subject.emtreeDrug potency
dc.subject.emtreeDrug synthesis
dc.subject.emtreeEmbryo
dc.subject.emtreeMale
dc.subject.emtreeMouse
dc.subject.emtreeNonhuman
dc.subject.emtreeStructure activity relation
dc.subject.meshAngiogenesis inhibitors
dc.subject.meshAnimals
dc.subject.meshChick embryo
dc.subject.meshChorioallantoic membrane
dc.subject.meshDrug evaluation, preclinical
dc.subject.meshFibroblast growth factors
dc.subject.meshHemoglobins
dc.subject.meshMice
dc.subject.meshStructure-activity relationship
dc.subject.meshThyroxine
dc.subject.scopusTetraiodothyroacetic Acid; Thyroid Hormones; Nano-Diamino-Tetrac
dc.subject.wosChemistry, medicinal
dc.subject.wosChemistry, organic
dc.titleSemisynthesis and pharmacological activities of tetrac analogs: Angiogenesis modulators
dc.typeArticle
dc.wos.quartileQ2
dspace.entity.typePublication
local.contributor.departmentVeteriner Fakültesi/Fizyoloji Ana Bilim Dalı
local.indexed.atPubMed
local.indexed.atWOS

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