Yayın: Semisynthesis and pharmacological activities of tetrac analogs: Angiogenesis modulators
Tarih
Kurum Yazarları
Yalçın, Murat
Yazarlar
Bridoux, Alexandre
Cui, Huadong
Dyskin, Evgeny A.
Mousa, Shaker A.
Danışman
Dil
Türü
Yayıncı:
Pergamon-Elsevier Science
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Özet
Novel Tetrac analogs were synthesized and then tested. Anti-angiogenesis efficacy was carried out using the Chick Chorioallantoic Membrane (CAM) model and the mouse matrigel model for angiogenesis. Pharmacological activities showed Tetrac can accommodate numerous modifications and maintain anti-angiogenesis activity.
Açıklama
Kaynak:
Anahtar Kelimeler:
Konusu
Angiogenesis, Esterification, HPLC, Nanopharmaceutical technology, Silylation, Tetrac, Integrin alpha-v-beta-3, Extracellular segment, Crystal-structure, Triiodothyronine, Thyroxine, Ligand, Acid, Pharmacology & pharmacy, Chemistry
Alıntı
Bridoux, A. vd. (2009). "Semisynthesis and pharmacological activities of tetrac analogs: Angiogenesis modulators". Bioorganic and Medicinal Chemistry Letters, 19(12), 3259-3263.