Publication:
Oxidative stress and intracranial hypertension after aneurysmal subarachnoid hemorrhage

dc.contributor.authorHao, Guangshan
dc.contributor.authorMo, Jun
dc.contributor.buuauthorEser, Pınar
dc.contributor.departmentTıp Fakültesi
dc.contributor.departmentNöroşurji Ana Bilim Dalı
dc.contributor.orcid0000-0003-0132-9927
dc.contributor.researcheridABD-7803-2022
dc.contributor.researcheridAAI-2073-2021
dc.contributor.researcheridHGC-8867-2022
dc.date.accessioned2024-10-08T12:27:13Z
dc.date.available2024-10-08T12:27:13Z
dc.date.issued2022-12-01
dc.description.abstractIntracranial hypertension is a common phenomenon in patients with aneurysmal subarachnoid hemorrhage (aSAH). Elevated intracranial pressure (ICP) plays an important role in early brain injuries and is associated with unfavorable outcomes. Despite advances in the management of aSAH, there is no consensus about the mechanisms involved in ICP increases after aSAH. Recently, a growing body of evidence suggests that oxidative stress (OS) may play a crucial role in physio-pathological changes following aSAH, which may also contribute to increased ICP. Herein, we discuss a potential relation between increased ICP and OS, and resultantly propose antioxidant mechanisms as a potential therapeutic strategy for the treatment of ICP elevation following aSAH.
dc.description.sponsorshipNational Natural Science Foundation of China (NSFC) -- 81901336
dc.identifier.doi10.3390/antiox11122423
dc.identifier.issue12
dc.identifier.scopus2-s2.0-85144834574
dc.identifier.urihttps://doi.org/10.3390/antiox11122423
dc.identifier.urihttps://hdl.handle.net/11452/46091
dc.identifier.volume11
dc.identifier.wos000900352000001
dc.indexed.wosWOS.SCI
dc.language.isoen
dc.publisherMdpi
dc.relation.journalAntioxidants
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectEarly brain-injury
dc.subjectCerebral-blood-flow
dc.subjectNitric-oxide synthase
dc.subjectCerebrospinal-fluid
dc.subjectIntracerebral hemorrhage
dc.subjectBarrier disruption
dc.subjectTime-course
dc.subjectPressure
dc.subjectMyeloperoxidase
dc.subjectExpression
dc.subjectSubarachnoid hemorrhage
dc.subjectOxidative stress
dc.subjectIntracranial hypertension
dc.subjectBrain injury
dc.subjectAntioxidant
dc.subjectScience & technology
dc.subjectLife sciences & biomedicine
dc.subjectBiochemistry & molecular biology
dc.subjectChemistry, medicinal
dc.subjectFood science & technology
dc.subjectBiochemistry & molecular biology
dc.subjectPharmacology & pharmacy
dc.subjectFood science & technology
dc.titleOxidative stress and intracranial hypertension after aneurysmal subarachnoid hemorrhage
dc.typeReview
dspace.entity.typePublication
local.contributor.departmentTıp Fakültesi/Nöroşurji Ana Bilim Dalı
local.indexed.atWOS
local.indexed.atScopus

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