Publication:
The beneficial effect of cyclosporin-A on the no-reflow phenomenon in rat skin island flaps

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dc.contributor.buuauthorKücükçelebi, Ahmet
dc.contributor.buuauthorÖzcan, M.
dc.contributor.researcheridAAZ-1076-2020
dc.date.accessioned2021-07-01T05:43:24Z
dc.date.available2021-07-01T05:43:24Z
dc.date.issued1992
dc.description.abstractThe no-reflow phenomenon is one of the factors that increase morbidity in flap and replantation surgery. Prevention and treatment of the phenomenon is an area of intense current research. This study investigated the possible effect of cyclosporin administered systemically on survival of skin flaps subjected to ischaemia-reperfusion injury. Cyclosporin treated flaps showed a statistically significant increase in survival areas regardless of the time of infusion (p < 0.01). These findings suggest that cyclosporin could be valuable in preventing or treating no-reflow in critical flaps. Possible mechanisms of action are discussed.
dc.identifier.citationKüçükçelebi, A. ve Özcan, M. (1992). ''The beneficial effect of cyclosporin-A on the no-reflow phenomenon in rat skin island flaps''. British Journal of Plastic Surgery, 45(7), 512-514.
dc.identifier.endpage514
dc.identifier.issn0007-1226
dc.identifier.issue7
dc.identifier.pubmed1446193
dc.identifier.scopus2-s2.0-0026743057
dc.identifier.startpage512
dc.identifier.urihttps://doi.org/10.1016/0007-1226(92)90144-M
dc.identifier.urihttps://www.sciencedirect.com/science/article/abs/pii/000712269290144M
dc.identifier.urihttp://hdl.handle.net/11452/20944
dc.identifier.volume45
dc.identifier.wosA1992JV35300004
dc.indexed.scopusScopus
dc.indexed.wosSCIE
dc.language.isoen
dc.publisherChurchill Livingstone
dc.relation.journalBritish Journal of Plastic Surgery
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectLiver
dc.subjectSurgery
dc.subject.wosSurgery
dc.titleThe beneficial effect of cyclosporin-A on the no-reflow phenomenon in rat skin island flaps
dc.typeArticle
dspace.entity.typePublication
local.indexed.atPubMed
local.indexed.atScopus

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