2020 Cilt 39 Sayı 1
Permanent URI for this collectionhttps://hdl.handle.net/11452/14471
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Item The effects of different monochromatic colors on oxidant antioxidant balance in broilers(Bursa Uludağ Üniversitesi, 2020-02-13) Seyidoğlu, Nilay; Belenli, Deniz; Merhan, Oğuz; Bozukluhan, KadirPoultry management is associated with light due to positive effects of photoreceptors on animal’s growth, immunity and homeostasis. Colors influence the efficiency of poultry performance and behavior. Light-emitting diode (LED) can use for providing monochromatic light source. In this trial, two hundred Ross 308 broiler chicks were studied in four different light groups as follows; White (Control), Red (RL), green (GL) and blue (BL) during 42 trial days. At the end of the study, the serum Superoxide dismutase (SOD), Catalase (CAT), Glutathione Peroxidase (GPx) and malondialdehyde (MDA) enzyme activities were measured to evaluate the oxidant-antioxidant balance. The oxidant marker MDA was found the highest value in group RL (p:0.0001 ; 9.24±0.33). On the other hand, in group GL, all antioxidant parameters were found the highest value (p<0.05). Also, SOD and GPx values were increased in group GL (SOD: 150.61±9.14 ; GPx: 186.96±10.50) than BL (SOD: 139.29±5.19; GPx: 160.02±3.15) statistically (p<0.05). The results showed that red light may be a stressor, and on the contrary, green light may be a positive monochromatic color for growth, oxidant-antioxidant balance and homeostasis for broilers.Item Effects of lacosamide in rats with lipopolysaccharide ınduced hepatic pathology(Bursa Uludağ Üniversitesi, 2020-05-21) Özmen, Özlem; İpek, VolkanBacterial lipopolysaccharides (LPS) generally increase the pathogenicity of the agent. This study aimed to examine the hepatic pathology and possible prophylactic effects of lacosamide (LCM) in a LPS-induced sepsis rat model. Overall, 24 1-year-old female Wistar Albino rats were divided into three groups: Group I (control), Group II (LPS group: 5 mg/kg LPS intraperitoneally, single dose), and Group III (LCM group: 40 mg/kg LCM intraperitoneally once daily for 3 days plus 5 mg/kg LPS 30 min after the last LCM treatment). Animals were euthanized 6 hours after LPS administration. Blood and liver samples collected during necropsy were analyzed biochemically, pathologically, and immunohistochemically. LPS caused a significant increase in serum aspartate aminotransferase, alanine aminotransferase, total bilirubin, direct bilirubin, indirect bilirubin, and alkaline phosphatase levels. Histopathological analysis revealed numerous neutrophil leucocyte infiltrations, slight hemorrhages in the liver, and degenerative or necrotic changes in hepatocytes. Increased expressions of malondialdehyde, C-reactive protein, heat shock protein-70, interleukin-1β, and tumor necrosis factor-α were observed in the LPS administered group. LCM ameliorated the biochemical, histopathological, and immunohistochemical findings. The present study results revealed that LCM ameliorated the LPS-induced liver damage in the rat models as evidenced by the biochemical and pathological findings.Item The morphometric examination of head area of black headed gulls (larus ridibundus) from marmara region(Bursa Uludağ Üniversitesi, 2020-02-24) Gündemir, Ozan; Pazvant, Gülsün; İnce, NazanThe Black-headed gull (Larus ridibundus), a gull species commonly seen on shores of Küçükçekmece lake located in Turkey’s Marmara Region. This bird does not show sexual dimorphism because as it has monomorphic feather characteristics like other gull species.. In order to perform sex discrimination in gulls, the effective discriminant function analysis (DFA) method is used for the measurements based on the external morphology and determining the variables discriminating the two sex groups. The head morphological measurements and the body weights of 28 (14 males and 14 females) adult Black-headed gulls were obtained. One discriminant function was determined based on the results. The accuracy rate in two sexes was determined to be 82.1% (85.7% female, 78.6% male) using the formula we obtained as a result of the discriminant function analysis in which the head length, determined to be more significant compared to the other variables, was used. The aim of the study is to assess the sexual dimorphism in population of Black-headed gull and represent a reliable method to make a sex discrimination along with discriminant analysis.Item A phylogenetic and genotyping study of bovine herpesvirus type 4 (bhv-4) in Turkey(Bursa Uludağ Üniversitesi, 2020-05-26) Koç, TaylanInfertility and reproductive infections are the huge problems for the diary management throughout the world. Bovine herpesviruses act an enormous role in these complicated problems. Bovine Herpesvirus Type 1 (BHV-1) is the most outstanding herpesvirus causing genital and uterine tracts infections among other reproductive viral agents, however, Bovine Herpesvirus Type 4 (BHV-4) is also responsible in terms of similar symptoms and diseases. The main aims of the study are both to investigate the underlying potential presence of BHV-4 in subclinical uterine tract infection, and both to perform molecular and recombination analyses. A herd including 25 repeat breeder cows were investi-gated by BHV-4. Two out of them were determined BHV-4 infected after a series of Polymerase Chain Reactions (PCRs) tests which able to amplify partial Glycoprotein B (gB) and Thymidine Kinase (TK) gene regions. Obtained sequences were analyzed by using phylogenetic and recombinational software, and two Maximum Likelihood (ML) tree have been constructed. To results, novel Turkish BHV-4 sequences fell into Genotype I in both constructed Maximum Likelihood (ML) phylogenetic trees, however, no recombination evidence has been observed in relevant software. This report is one of the rare genotyping studies on BHV-4 from Turkey. This study showed that Turkish BHV-4 strains, as molecular, were highly probable to originate from European strains and might be observed in different clinical reflections. This suggests that BHV-4 should be deeply investigated by further molecular techniques and included in diagnostic panels for reproductive viruses.Item Ultrasound follow-up of adhesions after one-step laparoscopic abomasopexy for correction of left displaced abomasum in cattle(Bursa Uludağ Üniversitesi, 2019-11-11) Ayalp, Göksen Çeçen; Şen, İsmail Altuğ; Satar, Nihal Yaşar Gül; Sert, Sibel Tokoğlu; Uludağ Üniversitesi/Veteriner Fakültesi.; 0000-0001-8537-0761; 0000-0003-1312-7361; 0000-0002-5027-0784; 0000-0002-5027-0784The objective of this study was to evaluate the use of ultrasonography on the determination of the thickness of adhesion formation at the abomasopexy site in cows which had undergone one-step laparoscopic abomasopexy. Ten Holstein cows with left displaced abomasum (LDA) were included in the study. Animals were treated with one-step laparoscopic abomasopexy whilst standing. Postoperative ultrasonographic examinations were carried out starting immediately after surgery (day 0), and on days 28, 90 and 120 by using a 5 MHz linear transducer. The thickness of the adhesion formation was measured between the abdominal wall and the abomasum. Ultrasonographic image revealed the area of fixation on day 0 as a mild distorted subcutaneous tissue. A heterogeneous hypoechoic irregular-shaped mass (adhesion) was observed between the abomasum and abdominal wall on days 28, 90 and 120. Average thickness significantly (p <0.05) increased from day 0 to day 28, but tended to decrease afterwards. The average thickness at the abomasopexy site was recorded as 20.47, 22.82, 22.34 and 21.92mm on days 0, 28, 90 and 120, respectively. Ultrasonographic examination can diagnose and measure adhesions between the abomasum and the abdominal wall. During the study period, adhesion formation was followed up to the 120th day, and in this period the thickness of the adhesion tended to decrease. Long follow-up studies are thought to be beneficial to determine the difference in adhesion thickness.