PubMed

Permanent URI for this collectionhttps://hdl.handle.net/11452/24864

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Body fat distribution has no effect on serum visfatin levels in healthy female subjects
(Academic Press - Elsevier Science, 2010-03) Ersoy, Canan; Sadıkoğlu, Ganime; Orhan, Hasan; Güçlü, Metin; Sarandöl, Emre; Akgün, Meral Demirci; Özçakır, Alis; İmamoğlu, Şazi; Tıp Fakültesi; Tıbbi Biyokimya Ana Bilim Dalı; 0000-0002-2593-7196; 0000-0001-5588-2037; ABI-4847-2020; ABE-1716-2020; AAG-8209-2021; AAH-8861-2021; 6701485882; 22956348700; 36126806400; 15073842600; 55943324800; 36125941900; 9733230000; 6602297533
Obesity is the presence of either abnormal absolute amount or relative proportion of body fat. Contrary to gluteal obesity, visceral obesity is associated with different metabolic alterations including insulin resistance (IR). A relatively new adipocytokine visfatin is shown to be expressed predominantly in visceral fat and exhibit insulin-mimicking effects in rodents. It is still unclear whether serum visfatin levels are associated with increased total or visceral fat mass in humans. The aim of our study was to investigate the relation between visfatin and obesity parameters namely body mass index (BMI) and waist circumference (WaC) and IR in healthy female subjects. Eighty one female subjects >= 20 years of age, having no diagnosis of glucose intolerance or diabetes, hypertension and dyslipidemia were chosen. The patients were divided into four groups according to their BMI and WaC values. Serum visfatin and HOMA-IR levels did not differ among groups. No correlation was detected between serum visfatin levels and obesity and metabolic parameters. In conclusion, we demonstrated that body fat distribution did not affect serum visfatin levels in healthy female subjects. Further studies are needed to clarify the exact factors influencing and determining serum visfatin levels and its clinical reflections.
Job related affective well-being among primary health care physicians
(Oxford University, 2007-10) Yeşim, Uncu; Bayram, Nuran; Bilgel, Nazan; İktisadi ve İdari Bilimler Fakültesi; Ekonometri Bölümü; 0000-0001-5492-184X; 0000-0002-5225-4403; 0000-0002-4539-5849; D-9597-2016; AAG-9068-2021; 8892370600; 13609585600; 7801564702
Background: Job related affective well-being is important for a healthy life and job satisfaction for all individuals, including physicians. The later group, however, is most often compromised. Objectives: We aimed to investigate a group of Turkish primary health care physicians' job related emotional perceptions and to assess their reactions in terms of stress, anxiety and depression. Methods: A descriptive, cross-sectional, self-reported questionnaire study was conducted. A total of 60 primary health care centres and 274 general practitioners who were working at these centres participated in the study. The response rate was 74%. Printed questionnaires were completed by the participants anonymously. We used the Job Related Affective Well-Being Scale (JAWS) and Depression Anxiety Stress Scale (DASS 42). Correlation analysis and hierarchic regression were performed. Results: Correlations between JAWS and DASS total scores were negative and statistically significant (r = -0.52; P< 0.01). Low pleasure/high arousal (LPHA) and low pleasure/low arousal (LPLA) variations that describe negative emotional states show a positive and significant relationship with depression, anxiety and stress values. The highest mean score was obtained for the high pleasure/low arousal (HPLA) status that can be interpreted to mean that our study group was pleased with their job but was not motivated. Conclusions: Physician's job related negative emotional perceptions are associated with reactions in terms of stress, anxiety and depression. For this reason, it is critical to consider primary care physicians' job related affectations and job related stimuli.
Mammography utilization among Turkish women
(Asian Pacific Organization Cancer Prevention, 2010) Sadıkoğlu, Ganime; Özçakır, Alis; Doğan, Fatma Oflu; Gökgöz, Şehsuvar; Bilgel, Nazan Gönül; Tıp Fakültesi; Genel Cerrahi Ana Bilim Dalı; 0000-0001-5588-2037; 0000-0002-4539-5849; AAG-8209-2021; 9733230000; 37080414800; 6603238737; 7801564702; 22956348700
In Turkey, breast cancer is the leading type of cancer and cause of cancer-related deaths among women, but information is limited on mammography practices. The objectives of the present study were to identify associations between attitudes and knowledge about mammography and socio-demographic indicators and having a mammogram. The participants of this cross-sectional and descriptive study were 1,208 women who attended the primary health care unit serving as a training unit of the medical faculty or the outpatient clinic for breast diseases of the same medical faculty's hospital between October and December 2007. A printed questionnaire covering socio-demographic variables, family history of breast cancer, mammography practices, and attitudes and knowledge of mammography was filled out in face-to-face interviews with the authors. Women with previously diagnosed breast cancer were excluded from the study. We performed chi square and logistic regression analyses. We found that 12.7% of the women had no knowledge of mammography, and 57.3 % had never had a mammogram. Fifty point six percent of our study group reported that they had had a clinical breast examination at least once, and 51.1% were aware of breast self examination (BSE). Need factors such as age and health-system-related factors such as awareness of BSE and having CBE were found to be more important than the socio-economic factors in mammography use. Mammography was accepted by 92.3% as a useful screening method for early detection of breast cancer and as a necessity for women of 50 years and over by the 90.6% of the study group. We found a positive attitude towards mammography and its importance but limited usage.
A meta-analysis and an evaluation of trends in obesity prevalence among children and adolescents in Turkey: 1990 through 2015
(Galenos Publishing House, 2018-03) Alper, Züleyha; Ercan, İlker; Uncu, Yeşim; Tıp Fakültesi; Aile Hekimliği Ana Bilim Dalı; 0000-0002-8349-9868; 0000-0002-5225-4403; ABE-2261-2020; ABF-2367-2020; D-9597-2016; 8580079400; 6603789069; 8892370600
Objective: Obesity in childhood and adolescence is one of the most serious public health problems due to a remarkable increase in prevalence in recent years and its close relationship with non-communicable diseases, such as diabetes and hypertension, resulting in increased adult morbidity and mortality. This study aims to quantify the secular trend in different regions of Turkey from 1990 to 2015 by performing a meta-analysis of childhood and adolescent obesity prevalence studies conducted. Methods: Uludag University Library Database was searched for relevant articles published prior to March 2017. The heterogeneity of the studies in the meta-analysis was tested by the I2 statistic and Cochran's Q test. The obesity trend analyses were examined by chi-square trend analysis with respect to five year periods. The statistical significance level was taken as alpha=0.05. Results: A total of 76 papers were initially identified addressing childhood and adolescent obesity in Turkey. Fifty-eight papers were selected for analysis. The prevalence of obesity increased from 0.6% to 7.3% with an 11.6-fold increase between the periods 1990-1995 to 2011-2015. The prevalence of obesity increased in both genders. However, boys were more likely to be obese than girls. Conclusion: Studies on obesity prevalence in the 5-19 age group in Turkey have gained importance, especially in the 2000s. While a remarkable number of prevalence studies, mostly regional, have been conducted between 2005-2011, a gradual decline was observed thereafter. Further national and population-based surveys on prevalence of obesity in children and adolescents are definitely needed in Turkey.
Prevalence of depression, anxiety, stress, and anger in turkish prisoners
(Wiley, 2013-05-17) Ünver, Yener; Yüce, Mehmet; Bayram, Nuran; Bilgel, Nazan Gönül; İktisadi ve İdari Bilimler Fakültesi; Kamu Maliyesi Bölümü; 0000-0001-5492-184X; 0000-0002-4539-5849; AAG-9068-2021; AAG-7390-2021; 57091324400; 13609585600; 7801564702
In Turkey, prison studies are rare and the mental health status of prisoners has not received proper attention. The purpose of this cross-sectional and descriptive study was to assess the prevalence of depression, anxiety, stress, and anger among a group of Turkish prisoners. Two self-reporting instruments (the Depression Anxiety Stress Scale-42 and Multidimensional Anger Scale) were filled out by 685 prisoners. Prisoners in the study group were found to be depressive, anxious, and stressed. Anger symptoms and aggressive behaviors were found to be at a moderate level. Prisoners with a history of being subjected to domestic violence in childhood had higher depression, anxiety, and stress scores than those without such a history. Young prisoners, those who had been previously imprisoned, with substance dependency and higher stress and anxiety levels reported more anger symptoms than others. Psychological support, together with stress and anger management programs, seems to be essential.
To evaluate the differences of risk factors in patients with lower extremity venous disease
(Saudi Medical Journal, 2007-08) Sadıkoğlu, Ganime; Özçakır, Aliş; Ercan, İlker; Özkaya, Güven; Sadıkoğlu, Yurtkuran M.; Tıp Fakültesi; Aile Hekimliği Ana Bilim Dalı; 0000-0001-5588-2037; 0000-0002-2382-290X; 0000-0003-0297-846X; FTO-3267-2022; AAG-8209-2021; ABF-2367-2020; A-4421-2016; INO-2041-2023; 22956348700; 9733230000; 6603789069; 16316866500; 6602402845
Objective: To determine whether there is a difference between risk factors in patients diagnosed to have clinically documented lower extremity venous disease after confirming the diagnosis radiologically by ultrasonographic and venographic evaluation. Methods: This study was performed from January 2002 to January 2005 in Bursa, the fourth biggest city of Turkey, situated in the west of the country in the Marmara Region. The study center is a private imaging center working in conjunction with the Department of Health, which performs diagnostic, and therapeutic vascular protocols in the region. Five hundred and fifty-three cases with clinically and radiologically documented diagnoses were evaluated with Multi-Variate Statistical Package 3.13 for the presence of pre-defined clusters of 14 different variables. Other statistical analyses were performed by the Statistical Package for Social Sciences, version 13.0. Results: Three different clusters were defined. The variables used to define the clusters were: age, gender, educational level, presence of smoking, amount of smoking (pack/per year), disease symptoms, presence of heart disease, and radiologically documented diagnosis. Conclusions: Chronic venous insufficiency and varicose veins are venous system diseases that are most commonly present in association with more than one concomitant risk factor.
Turkish general practitioners and complementary/alternative medicine
(Mary Ann Liebert, 2007-11) Mazıcıoğlu, M. Mümtaz; Özçakır, Aliş; Sadıkoğlu, Ganime; Bayram, Nuran; Bilgel, Nazan; Beyhan, Işık; Tıp Fakültesi; Ekonometri Bölümü; 0000-0001-5492-184X; 0000-0001-5588-2037; 0000-0002-4539-5849; AAG-9068-2021; AAG-8209-2021; 9733230000; 22956348700; 13609585600; 7801564702; 23027059100
Background: Complementary and alternative medicine (CAM) is in the spotlight of society. However, what is the position of physicians at this point? Objectives: To determine general practitioners' (GP) knowledge, attitudes, and approaches to CAM. Methods: All GPs (n = 521) practicing in Bursa Province, Turkey were surveyed by a questionnaire. Results: Responses from 49% of GPs were analyzed. Alltogether, most of our physicians (96.5%) had not received any education about CAM, wanted to learn more (74.4%), and their knowledge levels were low (60.8%). About half of them (51%) believed in the efficiency of CAM, whereas 38.0% did not. GPs desire more information about herbal medicine and acupuncture. Only 29% of GPs were using some type of CAM for themselves. Conclusions: GPs are aware of the subject's importance and want to learn more about CAM and improve their knowledge. It would be reasonable to provide training possibilities for GPs, primarily for the CAM types highly used by the population and most requested by the physicians.

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