Journal of Biological and Environmental Sciences

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Browsing by BUU Author "Akgül, Gülşah Demir"

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    Serum tumor necrosis factor - alpha alterations of dry cows vaccinated with inactive coronavirus, rotavirus, E. coli combined vaccine
    (Uludağ Üniversitesi, 2017-04-05) Mecitoğlu, Zafer; Akgül, Gülşah Demir; Catik, Serkan; Udum, Duygu; Batmaz, Hasan; Uludağ Üniversitesi/Veteriner Fakültesi/İç Hastalıkları Anabilim Dalı; Uludağ Üniversitesi/Veteriner Fakültesi/Biyokimya Anabilim Dalı.
    Tumor Necrosis Factor alpha (TNF-α) is a proinflamatory cytokine, closely associated with insulin resistance and related diseases such as type II ketosis and fatty liver of cows. Aim of the presented study was to investigate circulating levels of TNF-α after vaccinating dry cattle with inactive rotavirus, coronavirus and E.coli combined vaccine. 14 cattle were randomly assigned to two groups; vaccination group was vaccinated on days 0 and 21 of the study and control group not. Blood samples were collected on days 0, 1, 5, 15, 21, 22, 26, 36 of the study for evaluation of TNF-α and total leukocyte counts. Although not significant, TNF-α levels decreased in vaccination group after the second application. Total Leukocyte counts did not differ between and within groups. Results of the study demonstrates that vaccinating cattle with inactive rotavirus, coronavirus and E.coli combined vaccine in dry period does not induce alterations in circulating TNF-α levels.