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The progression of maternal RSV antibodies in the offspring

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Hacımustafaoğlu, Mustafa Kemal
Çelebi, Solmaz
Aynacı, E.
Sınırtaş, Melda
Köksal, Nilgün
Ercan, İlker
Göral, Güher
Ildırım, İbrahim

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Küçükerdoǧan, Aygün

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BMJ Publishing Group

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Abstract

The concentrations of maternal anti-RSV IgG antibodies were followed in 49 healthy newborns over the first six months of life. At birth, 41 mothers (83%) tested positive for anti-RSV IgG and all of their babies carried maternal anti-RSV IgG. Anti-RSV IgG positivity dropped to 73% at 1 month, 6% at 3 months, and 2% at 6 months. Between 3 and 6 months, 8% did acquire RSV infection, half of them as acute bronchiolitis and half as non-specific respiratory infection. All of the patients who acquired clinical RSV disease had an antibody concentration of <20 RU/ml which may be the cut off value for protection.

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Pediatrics, Syncytial virus-infection, Infants, Age

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Küçükerdoǧan, A. vd. (2004). “The progression of maternal RSV antibodies in the offspring”. Archives of Disease in Childhood, 89(1), 52-53.

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