Preoperative parathyroid hormone levels are correlated with parathyroid adenoma volume and bone mineral density but not serum calcium levels

Simple item page
dc.contributor.authorDuran, Cevdet
dc.contributor.buuauthorKıyıcı, Sinem Küçüksaraç
dc.contributor.buuauthorCander, Soner
dc.contributor.buuauthorGül, Özen Öz
dc.contributor.buuauthorSığırlı, Deniz
dc.contributor.buuauthorÜnal, Oğuz Kaan
dc.contributor.buuauthorSaraydaroǧlu, Özlem
dc.contributor.buuauthorErsoy, Canan
dc.contributor.buuauthorTuncel, Ercan
dc.contributor.buuauthorErtürk, Erdinç
dc.contributor.buuauthorİmamoğlu, Şazi
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Endokrinoloji ve Metabolizma Anabilim Dalı.tr_TR
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Biyoistatistik Anabilim Dalı.tr_TR
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Patoloji Anabilim Dalı.tr_TR
dc.contributor.researcheridAAJ-6536-2021tr_TR
dc.contributor.researcheridAAH-9701-2021tr_TR
dc.contributor.researcheridAAI-1005-2021tr_TR
dc.contributor.researcheridAAA-7472-2021tr_TR
dc.contributor.researcheridAAH-8861-2021tr_TR
dc.contributor.scopusid12753880400tr_TR
dc.contributor.scopusid25027068600tr_TR
dc.contributor.scopusid26040787100tr_TR
dc.contributor.scopusid24482063400tr_TR
dc.contributor.scopusid36716200600tr_TR
dc.contributor.scopusid15074395500tr_TR
dc.contributor.scopusid6701485882tr_TR
dc.contributor.scopusid7006929833tr_TR
dc.contributor.scopusid7005488796tr_TR
dc.contributor.scopusid6602297533tr_TR
dc.date.accessioned2022-11-09T13:24:42Z
dc.date.available2022-11-09T13:24:42Z
dc.date.issued2011-06
dc.description.abstractAim. The aim of this study was to determine the relationship between biochemical parameters, parathyroid adenoma volume, and bone mineral density with respect to intact parathyroid hormone (iPTH) levels in patients with primary hyperparathyroidism. Methods. Data were collected retrospectively from patients with primary hyperparathyroidism who were diagnosed and followed in our clinic between 2005 and 2008. Forty-eight (female/male=42/6) patients with a mean age of 52.8 +/- 13.1 years were enrolled into the study. Results. Bone pain was the most common presenting feature, seen in 41.7% of patients, while 29.1% of patients were asymptomatic. The mean serum calcium and iPTH concentrations were 2.9 +/- 0.6 mmol/L and 657.1 +/- 682 ng/L, respectively. The mean total Z/T scores of dual-energy X-ray absorptiometry (DEXA) scan at the femur and lumbar spine were -0.4 +/- 1.6/-1.0 +/- 1.7 and -1.4 +/- 1.6/-2.2 +/- 1.5, respectively. Preoperative iPTH levels were correlated with serum phosphate (r=-0.412, P=0.005), alkaline phosphatase (r=0.698, P=0.0001), and femur (r=-0.402, P=0.020) and lumbar spine total Z scores (r=-0.441, P=0.013), whereas parathyroid adenoma volume was correlated with iPTH (r=0.367, P=0.036) and alkaline phosphatase (r=0.570, P=0.001). There was no correlation between iPTH, serum calcium levels and total T scores at the femur and lumbar spine. After excluding patients with 25-OHD insufficiency, there was still no correlation between serum iPTH and calcium levels. Parathyroid adenoma volume, serum iPTH and calcium levels were also not different between patients with and without 25-OHD insufficiency. Conclusion. These results suggest that serum iPTH level may be useful in predicting parathyroid adenoma volume and it is also well correlated with femur and lumbar spine Z scores.en_US
dc.identifier.citationKıyıcı, S. vd. (2011). "Preoperative parathyroid hormone levels are correlated with parathyroid adenoma volume and bone mineral density but not serum calcium levels". Minerva Endocrinologica, 36(2), 123-128.en_US
dc.identifier.endpage128tr_TR
dc.identifier.issn0391-1977
dc.identifier.issn1827-1634
dc.identifier.issue2tr_TR
dc.identifier.pubmed21519321tr_TR
dc.identifier.scopus2-s2.0-79960621593tr_TR
dc.identifier.startpage123tr_TR
dc.identifier.urihttps://pubmed.ncbi.nlm.nih.gov/21519321/
dc.identifier.urihttp://hdl.handle.net/11452/29441
dc.identifier.volume36tr_TR
dc.identifier.wos000290776400004tr_TR
dc.indexed.pubmedPubMeden_US
dc.indexed.scopusScopusen_US
dc.indexed.wosSCIEen_US
dc.language.isoenen_US
dc.publisherEdizioni Minerva Medicaen_US
dc.relation.collaborationYurt içitr_TR
dc.relation.journalMinerva Endocrinologicaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectEndocrinology & metabolismen_US
dc.subjectHyperparathyroidism, primaryen_US
dc.subjectAdenomaen_US
dc.subjectParathyroid hormoneen_US
dc.subjectPrimary hyperparathyroidismen_US
dc.subjectLaboratory findingsen_US
dc.subjectWeighten_US
dc.subjectUltrasonographyen_US
dc.subject.emtree25 hydroxy Vitamin Den_US
dc.subject.emtreeAlkaline phosphataseen_US
dc.subject.emtreeCalciumen_US
dc.subject.emtreeParathyroid hormoneen_US
dc.subject.emtreePhosphateen_US
dc.subject.emtreeUnclassified drugen_US
dc.subject.emtreeVitamin Den_US
dc.subject.emtreeAdulten_US
dc.subject.emtreeAlkaline phosphatase blood levelen_US
dc.subject.emtreeArticleen_US
dc.subject.emtreeBone densityen_US
dc.subject.emtreeBone painen_US
dc.subject.emtreeCalcium blood levelen_US
dc.subject.emtreeClinical articleen_US
dc.subject.emtreeClinical featureen_US
dc.subject.emtreeDual energy X ray absorptiometryen_US
dc.subject.emtreeFemaleen_US
dc.subject.emtreeFemuren_US
dc.subject.emtreeHumanen_US
dc.subject.emtreeLaboratory testen_US
dc.subject.emtreeLumbar spineen_US
dc.subject.emtreeMaleen_US
dc.subject.emtreeParathyroid adenomaen_US
dc.subject.emtreeParathyroid hormone blood levelen_US
dc.subject.emtreePhosphate blood levelen_US
dc.subject.emtreePreoperative perioden_US
dc.subject.emtreePrimary hyperparathyroidismen_US
dc.subject.emtreeTumor volumeen_US
dc.subject.emtreeVitamin D deficiencyen_US
dc.subject.meshAbsorptiometry, photonen_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshBone densityen_US
dc.subject.meshCalciumen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle ageden_US
dc.subject.meshPainen_US
dc.subject.meshParathyroid hormoneen_US
dc.subject.meshParathyroid neoplasmsen_US
dc.subject.meshRetrospective studiesen_US
dc.subject.meshYoung adulten_US
dc.subject.scopusPrimary Hyperparathyroidism; Parathyroid Neoplasms; Methoxy Isobutyl Isonitrile Technetium Tc 99Men_US
dc.subject.wosEndocrinology & metabolismen_US
dc.titlePreoperative parathyroid hormone levels are correlated with parathyroid adenoma volume and bone mineral density but not serum calcium levelsen_US
dc.typeArticle
dc.wos.quartileQ4en_US

Files

License bundle
Now showing 1 - 1 of 1
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

Web of Science
PubMed
Scopus