Chandrakala SFCR The value of spectrophotometric intracutaneous analysis in the noninvasive diagnosis of nonmelanoma skin cancers

dc.contributor.buuauthorHacıoǧlu, Şenay
dc.contributor.buuauthorSarıcaoğlu, Hayriye
dc.contributor.buuauthorBaşkan, Emel Bülbül
dc.contributor.buuauthorUner, S. I.
dc.contributor.buuauthorAydoĝan, Kenan
dc.contributor.buuauthorTunalı, Şükran
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Dermatoloji Anabilim Dalı.tr_TR
dc.contributor.orcid0000-0002-0193-1128tr_TR
dc.contributor.researcheridAAH-6216-2021tr_TR
dc.contributor.scopusid36196495300tr_TR
dc.contributor.scopusid6603722836tr_TR
dc.contributor.scopusid6602518817tr_TR
dc.contributor.scopusid55914302400tr_TR
dc.contributor.scopusid9739755800tr_TR
dc.contributor.scopusid7004191748tr_TR
dc.date.accessioned2022-12-30T07:37:20Z
dc.date.available2022-12-30T07:37:20Z
dc.date.issued2013-06-18
dc.description.abstractBackground. Spectrophotometric intracutaneous analysis (SIAscopy) is a recently introduced, noninvasive, rapid and practical method for monitoring pigmented lesions, which calculates the amount of collagen, melanin and haemoglobin deep in the papillary dermis. Aim. To evaluate the value of SIAscopy in the diagnosis of nonmelanoma skin cancers (NMSC). Methods. In total, 80 lesions of 76 patients were clinically evaluated by the first investigator, and the data recorded. Eight months after the clinical evaluation, all lesions were evaluated again by the same investigator, using images (SIAgraphs) obtained by the SIAscope. All SIAgraphs were also evaluated by a second investigator, and all dermatoscopic images by a third, independently of each other. All diagnoses were compared with histopathological diagnoses. Results. The clinical diagnosis was calculated to have a sensitivity of 79% and specificity of 84%. The SIAscopic diagnoses of the first and second investigators had a sensitivity of 55% and 93%, and a specificity of 88% and 53%, respectively, while the dermatoscopic diagnoses of the third investigator had a sensitivity of 86% and specificity of 80%. There was no statistical accordance between the first and second investigators according to the accuracy of SIAscopic diagnoses (P<0.01). The area under the curve for the receiver operator characteristic was 0.82 for clinical diagnosis, 0.73 and 0.80 for the SIAscopic evaluation of the first and the second investigators, respectively, and 0.87 for the dermatoscopic evaluation of the third investigator. Conclusions. Our findings show that dermatoscopic findings are more valuable than SIAscopic and clinical findings for the noninvasive diagnosis of NMSC. We consider that SIAscopy makes no substantial contribution towards the differential diagnosis of NMSC.en_US
dc.identifier.citationHacıoǧlu, S. vd. (2013). "Chandrakala SFCR The value of spectrophotometric intracutaneous analysis in the noninvasive diagnosis of nonmelanoma skin cancers". Clinical and Experimental Dermatology, 38(5), 464-469.en_US
dc.identifier.endpage469tr_TR
dc.identifier.issn0307-6938
dc.identifier.issue5tr_TR
dc.identifier.pubmed23777487tr_TR
dc.identifier.scopus2-s2.0-84879235297tr_TR
dc.identifier.startpage464tr_TR
dc.identifier.urihttps://doi.org/10.1111/j.1365-2230.2012.04460.x
dc.identifier.urihttps://onlinelibrary.wiley.com/doi/10.1111/j.1365-2230.2012.04460.x
dc.identifier.urihttp://hdl.handle.net/11452/30178
dc.identifier.volume38tr_TR
dc.identifier.wos000320545000003tr_TR
dc.indexed.pubmedPubMeden_US
dc.indexed.scopusScopusen_US
dc.indexed.wosSCIEen_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.bapT-2007/18tr_TR
dc.relation.journalClinical and Experimental Dermatologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectDermatologyen_US
dc.subjectBasal-cell carcinomaen_US
dc.subjectOptical coherence tomographen_US
dc.subjectIn-vivoen_US
dc.subjectLesionsen_US
dc.subjectMicroscopyen_US
dc.subjectDermoscopyen_US
dc.subjectAccuracyen_US
dc.subject.emtreeCollagenen_US
dc.subject.emtreeHemoglobinen_US
dc.subject.emtreeMelaninen_US
dc.subject.emtreeActinic keratosisen_US
dc.subject.emtreeAdulten_US
dc.subject.emtreeArticleen_US
dc.subject.emtreeBasal cell carcinomaen_US
dc.subject.emtreeCancer diagnosisen_US
dc.subject.emtreeControlled studyen_US
dc.subject.emtreeDermatofibromaen_US
dc.subject.emtreeDiagnostic accuracyen_US
dc.subject.emtreeDiagnostic test accuracy studyen_US
dc.subject.emtreeDiagnostic valueen_US
dc.subject.emtreeEpiluminescence microscopyen_US
dc.subject.emtreeFemaleen_US
dc.subject.emtreeHistopathologyen_US
dc.subject.emtreeHumanen_US
dc.subject.emtreeImaging softwareen_US
dc.subject.emtreeInterrater reliabilityen_US
dc.subject.emtreeKeratoacanthomaen_US
dc.subject.emtreeMajor clinical studyen_US
dc.subject.emtreeMaleen_US
dc.subject.emtreeMelanomaen_US
dc.subject.emtreeNevusen_US
dc.subject.emtreeNon invasive procedureen_US
dc.subject.emtreeNon melanoma skin canceren_US
dc.subject.emtreePredictive valueen_US
dc.subject.emtreePriority journalen_US
dc.subject.emtreeSeborrheic keratosisen_US
dc.subject.emtreeSensitivity and specificityen_US
dc.subject.emtreeSpectrophotometric intracutaneous analysisen_US
dc.subject.emtreeSpectrophotometryen_US
dc.subject.emtreeSquamous cell carcinomaen_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshAged, 80 and overen_US
dc.subject.meshCollagenen_US
dc.subject.meshDermoscopyen_US
dc.subject.meshDiagnosis, differentialen_US
dc.subject.meshFemaleen_US
dc.subject.meshHemoglobinsen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMelaninsen_US
dc.subject.meshMiddle ageden_US
dc.subject.meshObserver variationen_US
dc.subject.meshPredictive value of testsen_US
dc.subject.meshSensitivity and specificityen_US
dc.subject.meshSkin neoplasmsen_US
dc.subject.meshSpectrophotometryen_US
dc.subject.meshYoung adulten_US
dc.subject.scopusDermoscopy; Melanoma; Dysplastic Nevusen_US
dc.subject.wosDermatologyen_US
dc.titleChandrakala SFCR The value of spectrophotometric intracutaneous analysis in the noninvasive diagnosis of nonmelanoma skin cancersen_US
dc.typeArticle
dc.wos.quartileQ3en_US

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