Schizophrenia and schizophrenia-like psychotic epilepsy: An electrophysiological-biochemical correlation

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dc.contributor.authorÖzaşkınlı, Suha
dc.contributor.authorKarakılıç, İlknur Demir
dc.contributor.authorKaraaslan, Ferdi
dc.contributor.authorPektoylan, T.
dc.contributor.buuauthorTaneli, Bilgen
dc.contributor.buuauthorTaneli, Suna
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Ruh Sağlığı ve Hastalıkları Anabilim Dalı.tr_TR
dc.contributor.scopusid6603520984tr_TR
dc.contributor.scopusid6507993732tr_TR
dc.date.accessioned2021-07-26T07:53:53Z
dc.date.available2021-07-26T07:53:53Z
dc.date.issued1988
dc.description.abstractIn this study, 15 schizophrenic depressives (SD) with normal EEGs, 17 schizophrenia-like psychotic epilepsy (SLPE) cases with hypersynchronous EEG pathology, but with no epileptic seizures in their medical histories, and 24 healthy control subjects were included. The dexamethasone suppression test (DST) has been used to compare SD and SLPE. Out of 15 patients with SD, 13 (86.67%) had a plasma cortisol concentration higher than 5 μg/dl in the predexamethasone sample taken at 11:00 p.m. Regarding post dexamethasone samples, 8 (53.33%) in their 4:00 p.m. samples and 11 (73.33%) in their 11:00 p.m. samples showed early escape from suppression. Mean values of serum cortisol concentrations were as follows: predexamethasone, 12.63 ± 7.32 μg/dl; postdexamethasone 7.96 ± 7.79 μg/dl at 4:00 p.m. and 9.31 ± 8.97 μg/dl at 11:00 p.m. Out of the 17 SLPE cases, 12 (70.59%) had a plasma cortisol concentration higher than or equal to 5 μg/dl in their 11:00 p.m. predexamethasone blood samples. 2 (11.76%) in their 4:00 p.m. and 3 (17.60%) in their 11:00 p.m. postdexamethasone blood samples showed early escape from suppression. Mean values of serum cortisol concentration were as follows: predexamethasone, 7.15 ± 5.02 μg/dl; postdexamethasone 2.49 ± 2.09 μg/dl at 4:00 p.m. and 3.24 ± 3.44 μg/dl at 11:00 p.m. It was concluded through this research, that two groups of patients with the same clinical symptomatology had actually different aetiologies. SD is an endogenous psychosis, on the other hand SLPE an epileptic phenomenon.en_US
dc.identifier.citationTaneli, B. vd. (1988). ''Schizophrenia and schizophrenia-like psychotic epilepsy: An electrophysiological-biochemical correlation''. Research Communications in Psychology Psychiatry and Behavior, 13(1-2), 129-139.en_US
dc.identifier.endpage139tr_TR
dc.identifier.issn0362-2428
dc.identifier.issue1-2tr_TR
dc.identifier.scopus2-s2.0-0023910861tr_TR
dc.identifier.startpage129tr_TR
dc.identifier.urihttp://hdl.handle.net/11452/21285
dc.identifier.volume13tr_TR
dc.identifier.wosA1988N055800012tr_TR
dc.indexed.scopusScopusen_US
dc.indexed.wosSCIEen_US
dc.indexed.wosSSCIen_US
dc.language.isoenen_US
dc.publisherP.J.D. Publicationstr_TR
dc.relation.collaborationYurt içitr_TR
dc.relation.journalResearch Communications in Psychology Psychiatry and Behavioren_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subject.emtreeDepressionen_US
dc.subject.emtreeDexamethasone suppression testen_US
dc.subject.emtreeElectroencephalogramen_US
dc.subject.emtreeEpilepsyen_US
dc.subject.emtreePsychological aspecten_US
dc.subject.emtreePsychosisen_US
dc.subject.emtreeSchizophreniaen_US
dc.subject.wosPsychology, experimentalen_US
dc.subject.wosPsychologyen_US
dc.subject.wosPsychiatryen_US
dc.subject.wosBehavioral sciencesen_US
dc.subject.wosPsychology, biologicalen_US
dc.titleSchizophrenia and schizophrenia-like psychotic epilepsy: An electrophysiological-biochemical correlationen_US
dc.typeArticle

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