Evaluation of diagnostic findings and scoring systems in outcome prediction in acute pancreatitis

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dc.contributor.authorDervişoğlu, Adem
dc.contributor.authorPolat, Cafer
dc.contributor.buuauthorKaya, Ekrem
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Cerrahi Bilimler Bölümü.tr_TR
dc.contributor.orcid0000-0002-9562-4195tr_TR
dc.contributor.researcheridAAG-7319-2021tr_TR
dc.contributor.scopusid7004568109tr_TR
dc.date.accessioned2022-08-18T07:21:48Z
dc.date.available2022-08-18T07:21:48Z
dc.date.issued2007-06-14
dc.description.abstractAIM: To determine factors related to disease severity, mortality and morbidity in acute pancreatitis. METHODS: One hundred and ninety-nine consecutive patients were admitted with the diagnosis of acute pancreatitis (AP) in a 5-year period (1998-2002). In a prospective design, demographic data, etiology, mean hospital admission time, clinical, radiological, biochemical findings, treatment modalities, mortality and morbidity were recorded. Endocrine insufficiency was investigated with oral glucose tolerance test. The relations between these parameters, scoring systems (Ranson, Imrie and APACHE II) and patients' outcome were determined by using invariable tests and the receiver operating characteristics curve. RESULTS: One hundred patients were men and 99 were women; the mean age was 55 years. Biliary pancreatitis was the most common form, followed by idiopathic pancreatitis (53% and 26%, respectively). Sixty-three patients had severe pancreatitis and 136 had mild disease. Respiratory rate > 20/min, pulse rate > 90/min, increased C-reactive protein (CRP), lactate dehydrogenase (LDH) and aspartate aminotransferase (AST) levels, organ necrosis > 30% on computed tomography (CT) and leukocytosis were associated with severe disease. The rate of glucose intolerance, morbidity and mortality were 24.1%, 24.8% and 13.6%, respectively. CRP > 142 mg/L, BUN > 22 mg/dL, LDH > 667 U/L, base excess > -5, CT severity index > 3 and APACHE score > 8 were related to morbidity and mortality. CONCLUSION: APACHE H score, LDH, base excess and CT severity index have prognostic value and CRP is a reliable marker for predicting both mortality and morbidity.en_US
dc.identifier.citationKaya, E. vd. (2007). "Evaluation of diagnostic findings and scoring systems in outcome prediction in acute pancreatitis". World Journal of Gastroenterology, 13(22), 3090-3094.en_US
dc.identifier.endpage3094tr_TR
dc.identifier.issn10079327
dc.identifier.issue22tr_TR
dc.identifier.pubmed17589925tr_TR
dc.identifier.scopus2-s2.0-34447284746tr_TR
dc.identifier.startpage3090tr_TR
dc.identifier.urihttps://doi.org/10.3748/wjg.v13.i22.3090
dc.identifier.urihttps://www.wjgnet.com/1007-9327/full/v13/i22/3090.htm
dc.identifier.urihttp://hdl.handle.net/11452/28241
dc.identifier.volume13tr_TR
dc.identifier.wos000247640800011tr_TR
dc.indexed.pubmedPubMeden_US
dc.indexed.scopusScopusen_US
dc.indexed.wosSCIEen_US
dc.language.isoenen_US
dc.publisherBaishideng Publishing Groupen_US
dc.relation.collaborationYurt içitr_TR
dc.relation.journalWorld Journal of Gastroenterologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAcute pancreatitisen_US
dc.subjectNecrotizing pancreatitisen_US
dc.subjectSeverityen_US
dc.subjectAPACHE IIen_US
dc.subjectC-reactive proteinen_US
dc.subjectCT severity indexen_US
dc.subjectMortalityen_US
dc.subjectNecrosisen_US
dc.subjectRansonen_US
dc.subjectAuditen_US
dc.subjectDeathen_US
dc.subject.emtreeAPACHEen_US
dc.subject.emtreeAcute pancreatitisen_US
dc.subject.emtreeAdolescenten_US
dc.subject.emtreeAdulten_US
dc.subject.emtreeAgeden_US
dc.subject.emtreeAlanine aminotransferase blood levelen_US
dc.subject.emtreeAlkaline phosphatase blood levelen_US
dc.subject.emtreeAlkalosisen_US
dc.subject.emtreeArticleen_US
dc.subject.emtreeCarbapenem derivativeen_US
dc.subject.emtreeCholecystectomyen_US
dc.subject.emtreeAspartate aminotransferase blood levelen_US
dc.subject.emtreeBiliary tract diseaseen_US
dc.subject.emtreeDisease associationen_US
dc.subject.emtreeC reactive proteinen_US
dc.subject.emtreeComputer assisted tomographyen_US
dc.subject.emtreeFemaleen_US
dc.subject.emtreeAspartate aminotransferaseen_US
dc.subject.emtreeDisease severityen_US
dc.subject.emtreeEndocrine functionen_US
dc.subject.emtreeEndoscopic retrograde cholangiopancreatographyen_US
dc.subject.emtreeGlucose intoleranceen_US
dc.subject.emtreeUrea nitrogen blood levelen_US
dc.subject.emtreeHumanen_US
dc.subject.emtreeAlanine aminotransferaseen_US
dc.subject.emtreeHospital admissionen_US
dc.subject.emtreeIdiopathic diseaseen_US
dc.subject.emtreeLactate dehydrogenase blood levelen_US
dc.subject.emtreeLength of stayen_US
dc.subject.emtreeAlkaline phosphataseen_US
dc.subject.emtreeLeukocytosisen_US
dc.subject.emtreeMaleen_US
dc.subject.emtreeReceiver operating characteristicen_US
dc.subject.emtreeMajor clinical studyen_US
dc.subject.emtreeMorbidityen_US
dc.subject.emtreeMortalityen_US
dc.subject.emtreeOUtcome assessmenten_US
dc.subject.emtreeOral glucose tolerance testen_US
dc.subject.emtreePancreas necrosisen_US
dc.subject.emtreePancreas surgeryen_US
dc.subject.emtreePredictionen_US
dc.subject.emtreePrognosisen_US
dc.subject.emtreeProtein blood levelen_US
dc.subject.emtreePulse rateen_US
dc.subject.emtreeLactate dehydrogenaseen_US
dc.subject.emtreeNitrogenen_US
dc.subject.emtreeGuinoline derived antiinfective agenten_US
dc.subject.emtreeUreaen_US
dc.subject.scopusPancreatitis; Gallstones; Pancreas Pseudocysten_US
dc.subject.wosGastroenterology & hepatologyen_US
dc.titleEvaluation of diagnostic findings and scoring systems in outcome prediction in acute pancreatitisen_US
dc.typeArticle

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