Corneal sensitivity and ocular surface changes following preserved amniotic membrane transplantation for nonhealing corneal ulcers

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dc.contributor.buuauthorDoğru, Murat
dc.contributor.buuauthorYıldız, Meral
dc.contributor.buuauthorBaykara, Mehmet
dc.contributor.buuauthorÖzçetin, Hikmet
dc.contributor.buuauthorErtürk, Haluk
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Göz Hastalıkları Anabilim Dalı.tr_TR
dc.contributor.scopusid7006540932tr_TR
dc.contributor.scopusid35791194600tr_TR
dc.contributor.scopusid23093006700tr_TR
dc.contributor.scopusid6603402155tr_TR
dc.contributor.scopusid7003716972tr_TR
dc.date.accessioned2022-03-11T09:00:01Z
dc.date.available2022-03-11T09:00:01Z
dc.date.issued2003-03
dc.description.abstractIn summary, we found that AMT can be helpful for the treatment of epithelial defects and stromal ulcers. We came to learn that cases with total limbal deficiency or extensive ocular surface inflammation may not be cured with AMT alone. AMT provides improvement of corneal sensitivity, tear film stability and impression cytology parameters. However, the entire mechanism of the healing effect of amniotic membrane is still unknown. A recent experimental study revealed that amniotic membrane transplantation vs tarsorraphy in murine HSV-1 stromal keratitis resulted in improvements in substance-P-related corneal nerve fibres in eyes treated with amniotic membrane, but not in eyes treated with tarsorraphy. We think that prospective, controlled, comparative studies of corneal ulcers treated by, for instance, tarsorraphy or other modalities should be performed to investigate whether the beneficial changes of amniotic membrane transplantation are greater or lesser than the changes that might have been observed by an alternative treatment. In this study, we tried to point to the effects of amniotic membrane transplantation on the ocular surface together with the problematic and unresolved issues. Thus, it is our sincere belief that further studies should be carried out along these lines.en_US
dc.identifier.citationDoğru, M. vd. (2003). “Corneal sensitivity and ocular surface changes following preserved amniotic membrane transplantation for nonhealing corneal ulcers”. Eye, 17(2), 139-148.en_US
dc.identifier.endpage148tr_TR
dc.identifier.issn0950-222X
dc.identifier.issue2tr_TR
dc.identifier.pubmed12640399tr_TR
dc.identifier.scopus2-s2.0-0037357140tr_TR
dc.identifier.startpage139tr_TR
dc.identifier.urihttps://doi.org/10.1038/sj.eye.6700346
dc.identifier.urihttps://www.nature.com/articles/6700346
dc.identifier.urihttp://hdl.handle.net/11452/24954
dc.identifier.volume17tr_TR
dc.identifier.wos000182793700007tr_TR
dc.indexed.pubmedPubmeden_US
dc.indexed.scopusScopusen_US
dc.indexed.wosSCIEen_US
dc.language.isoenen_US
dc.publisherSpringernatureen_US
dc.relation.journalEyetr_TR
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectOphthalmologyen_US
dc.subjectEpithelial defectsen_US
dc.subjectBasement-membraneen_US
dc.subjectReconstructionen_US
dc.subjectUlcerationen_US
dc.subjectModelen_US
dc.subject.emtreeSubstance ptr_TR
dc.subject.emtreeAdulten_US
dc.subject.emtreeAgeden_US
dc.subject.emtreeAmnionen_US
dc.subject.emtreeArticleen_US
dc.subject.emtreeCellular parametersen_US
dc.subject.emtreeClinical articleen_US
dc.subject.emtreeControlled studyen_US
dc.subject.emtreeCornea epitheliumen_US
dc.subject.emtreeCornea limbusen_US
dc.subject.emtreeCornea sensibilityen_US
dc.subject.emtreeCornea stromaen_US
dc.subject.emtreeCornea ulceren_US
dc.subject.emtreeCytologyen_US
dc.subject.emtreeFemaleen_US
dc.subject.emtreeFetal tissue transplantationen_US
dc.subject.emtreeHerpes simplex keratitisen_US
dc.subject.emtreeHerpes simplex virus 1en_US
dc.subject.emtreeHumanen_US
dc.subject.emtreeInflammationen_US
dc.subject.emtreeMaleen_US
dc.subject.emtreeTear filmen_US
dc.subject.scopusKeratin-3; Amnion; Corneatr_TR
dc.subject.wosOphthalmologyen_US
dc.titleCorneal sensitivity and ocular surface changes following preserved amniotic membrane transplantation for nonhealing corneal ulcersen_US
dc.typeArticle
dc.wos.quartileQ2en_US

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