Simultaneous occurrence of synchronous and metachronous tumors with gastrointestinal stromal tumors
Tarih
2011
Kurum Yazarları
Süreli Yayın başlığı
Süreli Yayın ISSN
Cilt Başlığı
Yayınevi
Comenius
Özet
Objective: To examine the frequency and clinicopathological features of synchronous and metachronous tumors which occur simultaneously with gastrointestinal stromal tumors (GIST).
Methods: Clinical and pathologic records of 78 patients diagnosed with primary GIST and treated at our institution between 1997 and 2009 were reviewed.
Results: GIST occurred simultaneously with other primary GI malignancies in 16.1 % (n=13) of all patients with GIST. Of the simultaneous secondary tumors, 69.2 % (n=9) were gastrointestinal tumors, and the remaining were biliary system and breast tumors. GIST most frequently had gastric localization (n=6, 46.1 %).
Conclusion: Although GIST are uncommon neoplasms, their synchronous and metachronous coexistence with other tumors is rather frequent, mostly as incidental tumors accompanying a gastrointestinal neoplasm. Therefore, during surgery on cases with gastrointestinal neoplasms, the surgeon needs to be careful about a synchronous GIST. At the same time, more detailed studies are needed about the carcinogenesis of dual tumors coexisting with GIST (Tab. 1, Ref. 14).
Açıklama
Anahtar kelimeler
General & internal medicine, Gastrointestinal stromal tumor, Synchronous tumor, Metachronous tumor, Gist, Coexistence, Carcinoma, Neoplasms, Diagnosis
Alıntı
Adım, S. B. vd. (2011). "Simultaneous occurrence of synchronous and metachronous tumors with gastrointestinal stromal tumors". Bratislava Medical Journal, 112(11), 623-625.