Ulva rigida improves carbohydrate metabolism, hyperlipidemia and oxidative stress in streptozotocin-induced diabetic rats
dc.contributor.buuauthor | Taş, Sibel | |
dc.contributor.buuauthor | Çelikler, Serap | |
dc.contributor.buuauthor | Ziyanok, Sedef Ayvalık | |
dc.contributor.buuauthor | Sarandöl, Emre | |
dc.contributor.buuauthor | Dirican, Melahat | |
dc.contributor.department | Uludağ Üniversitesi/Fen-Edebiyat Fakültesi/Biyoloji Anabilim Dalı. | tr_TR |
dc.contributor.department | Uludağ Üniversitesi/Tıp Fakültesi/Biyokimya Anabilim Dalı. | tr_TR |
dc.contributor.orcid | 0000-0002-2593-7196 | tr_TR |
dc.contributor.orcid | 0000-0002-4177-3478 | tr_TR |
dc.contributor.orcid | 0000-0001-6225-774X | tr_TR |
dc.contributor.researcherid | ABE-6873-2020 | tr_TR |
dc.contributor.researcherid | ABE-1716-2020 | tr_TR |
dc.contributor.researcherid | AAG-6985-2021 | tr_TR |
dc.contributor.researcherid | AAH-2767-2021 | tr_TR |
dc.contributor.scopusid | 7004343411 | tr_TR |
dc.contributor.scopusid | 8234554800 | tr_TR |
dc.contributor.scopusid | 15128398000 | tr_TR |
dc.contributor.scopusid | 55943324800 | tr_TR |
dc.contributor.scopusid | 6601919847 | tr_TR |
dc.date.accessioned | 2022-01-03T06:55:29Z | |
dc.date.available | 2022-01-03T06:55:29Z | |
dc.date.issued | 2011-03 | |
dc.description.abstract | This study was designed to investigate the effects of Ulva rigida, one of the green algae, on the lipid profile and oxidative-antioxidative systems in streptozotocin-induced diabetic rats. Forty Wistar rats randomly divided into four groups: control (C), control + U. rigida extract (C + URE), diabetes (D) and diabetes + U. rigida extract (D + URE). U. rigida (2%) was administered in drinking water for 5 weeks after the induction of diabetes. U. rigida reduced the blood glucose, serum total cholesterol, triglyceride levels and plasma and tissue malondialdehyde (MDA) levels in the D + URE group. Insulin levels were significantly higher in the D + URE than those of the D group. Serum total cholesterol and tissue MDA levels were reduced in the C + URE group. Whole blood glutathione peroxidase and erythrocyte superoxide dismutase activities were higher in the D and C + URE groups compared with the C group. Paraoxonase and arylesterase activities were lower in the D group while U. rigida increased paraoxonase activities in C + URE and D + URE groups. This is the first study which showed U. rigida has antidiabetic and antihyperlipidemic effects and improves oxidative stress in diabetic rats. We conclude that U. rigida might have a potential use as a protective and/or therapeutic agent in diabetes mellitus. | en_US |
dc.identifier.citation | Taş, S. vd. (2011). "Ulva rigida improves carbohydrate metabolism, hyperlipidemia and oxidative stress in streptozotocin-induced diabetic rats". Cell Biochemistry and Function, 29(2), 108-113. | en_US |
dc.identifier.endpage | 113 | tr_TR |
dc.identifier.issn | 0263-6484 | |
dc.identifier.issue | 2 | tr_TR |
dc.identifier.pubmed | 21370246 | tr_TR |
dc.identifier.scopus | 2-s2.0-79952217192 | tr_TR |
dc.identifier.startpage | 108 | tr_TR |
dc.identifier.uri | https://doi.org/10.1002/cbf.1729 | |
dc.identifier.uri | https://pubmed.ncbi.nlm.nih.gov/21370246/ | |
dc.identifier.uri | http://hdl.handle.net/11452/23804 | |
dc.identifier.volume | 29 | tr_TR |
dc.identifier.wos | 000288079400005 | tr_TR |
dc.indexed.pubmed | Pubmed | en_US |
dc.indexed.scopus | Scopus | en_US |
dc.indexed.wos | SCIE | en_US |
dc.language.iso | en | en_US |
dc.publisher | Wiley | en_US |
dc.relation.journal | Cell Biochemistry and Function | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi | tr_TR |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Biochemistry & molecular biology | en_US |
dc.subject | Cell biology | en_US |
dc.subject | Ulva rigida | en_US |
dc.subject | Diabetes | en_US |
dc.subject | Oxidative stress | en_US |
dc.subject | Antioxidant status | en_US |
dc.subject | Hyperlipidemia | en_US |
dc.subject | Serum paraoxonase activity | en_US |
dc.subject | Vanadyl sulfate | en_US |
dc.subject | Mellitus | en_US |
dc.subject | Antioxidant | en_US |
dc.subject | Extract | en_US |
dc.subject | Mice | en_US |
dc.subject | Atherosclerosis | en_US |
dc.subject | Aminoguanidine | en_US |
dc.subject | Hyperglycemia | en_US |
dc.subject | Complications | en_US |
dc.subject | Chlorophyta | en_US |
dc.subject | Rattus | en_US |
dc.subject | Rattus norvegicus | en_US |
dc.subject | Ulva rigida | en_US |
dc.subject.emtree | Algal extract | en_US |
dc.subject.emtree | Antidiabetic agent | en_US |
dc.subject.emtree | Aryldialkylphosphatase | en_US |
dc.subject.emtree | Arylesterase | en_US |
dc.subject.emtree | Drinking water | en_US |
dc.subject.emtree | Glutathione peroxidase | en_US |
dc.subject.emtree | Insulin | en_US |
dc.subject.emtree | Malonaldehyde | en_US |
dc.subject.emtree | Superoxide dismutase | en_US |
dc.subject.emtree | Ulva rigida extract | en_US |
dc.subject.emtree | Unclassified drug | en_US |
dc.subject.emtree | Alga | en_US |
dc.subject.emtree | Animal experiment | en_US |
dc.subject.emtree | Article | en_US |
dc.subject.emtree | Blood | en_US |
dc.subject.emtree | Carbohydrate metabolism | en_US |
dc.subject.emtree | Cholesterol blood level | en_US |
dc.subject.emtree | Diabetes mellitus | en_US |
dc.subject.emtree | Drug effect | en_US |
dc.subject.emtree | Enzyme activity | en_US |
dc.subject.emtree | Erythrocyte | en_US |
dc.subject.emtree | Glucose blood level | en_US |
dc.subject.emtree | Hyperlipidemia | en_US |
dc.subject.emtree | Insulin blood level | en_US |
dc.subject.emtree | Male | en_US |
dc.subject.emtree | Nonhuman | en_US |
dc.subject.emtree | Oxidative stress | en_US |
dc.subject.emtree | Priority journal | en_US |
dc.subject.emtree | Rat | en_US |
dc.subject.emtree | Streptozocin diabetes | en_US |
dc.subject.emtree | Tissue level | en_US |
dc.subject.emtree | Triacylglycerol blood level | en_US |
dc.subject.emtree | Ulva rigida | en_US |
dc.subject.mesh | Animals | en_US |
dc.subject.mesh | Blood glucose | en_US |
dc.subject.mesh | Carbohydrate metabolism | en_US |
dc.subject.mesh | Diabetes mellitus, experimental | en_US |
dc.subject.mesh | Disease models, animal | en_US |
dc.subject.mesh | Humans | en_US |
dc.subject.mesh | Hyperlipidemias | en_US |
dc.subject.mesh | Male | en_US |
dc.subject.mesh | Malondialdehyde | en_US |
dc.subject.mesh | Oxidative stress | en_US |
dc.subject.mesh | Plant preparations | en_US |
dc.subject.mesh | Random allocation | en_US |
dc.subject.mesh | Rats | en_US |
dc.subject.mesh | Rats, wistar | en_US |
dc.subject.mesh | Ulva | en_US |
dc.subject.scopus | Aryldialkylphosphatase; Arylesterase; Human PON1 Protein | en_US |
dc.subject.wos | Biochemistry & molecular biology | en_US |
dc.subject.wos | Cell Biology | en_US |
dc.title | Ulva rigida improves carbohydrate metabolism, hyperlipidemia and oxidative stress in streptozotocin-induced diabetic rats | en_US |
dc.type | Article | |
dc.wos.quartile | Q3 (Biochemistry & molecular biology) | en_US |
dc.wos.quartile | Q4 (Cell biology) | en_US |
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