Body fat distribution has no effect on serum visfatin levels in healthy female subjects

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dc.contributor.buuauthorErsoy, Canan
dc.contributor.buuauthorSadıkoğlu, Ganime
dc.contributor.buuauthorOrhan, Hasan
dc.contributor.buuauthorGüçlü, Metin
dc.contributor.buuauthorSarandöl, Emre
dc.contributor.buuauthorAkgün, Meral Demirci
dc.contributor.buuauthorÖzçakır, Alis
dc.contributor.buuauthorİmamoğlu, Şazi
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/İç Hastalıkları Anabilim Dalı.tr_TR
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Aile Hekimliği Anabilim Dalı.tr_TR
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Tıbbi Biyokimya Anabilim Dalı.tr_TR
dc.contributor.orcid0000-0002-2593-7196tr_TR
dc.contributor.orcid0000-0001-5588-2037tr_TR
dc.contributor.researcheridABI-4847-2020tr_TR
dc.contributor.researcheridABE-1716-2020tr_TR
dc.contributor.researcheridAAG-8209-2021tr_TR
dc.contributor.researcheridAAH-8861-2021tr_TR
dc.contributor.scopusid6701485882tr_TR
dc.contributor.scopusid22956348700tr_TR
dc.contributor.scopusid36126806400tr_TR
dc.contributor.scopusid15073842600tr_TR
dc.contributor.scopusid55943324800tr_TR
dc.contributor.scopusid36125941900tr_TR
dc.contributor.scopusid9733230000tr_TR
dc.contributor.scopusid6602297533tr_TR
dc.date.accessioned2022-04-25T13:23:00Z
dc.date.available2022-04-25T13:23:00Z
dc.date.issued2010-03
dc.description.abstractObesity is the presence of either abnormal absolute amount or relative proportion of body fat. Contrary to gluteal obesity, visceral obesity is associated with different metabolic alterations including insulin resistance (IR). A relatively new adipocytokine visfatin is shown to be expressed predominantly in visceral fat and exhibit insulin-mimicking effects in rodents. It is still unclear whether serum visfatin levels are associated with increased total or visceral fat mass in humans. The aim of our study was to investigate the relation between visfatin and obesity parameters namely body mass index (BMI) and waist circumference (WaC) and IR in healthy female subjects. Eighty one female subjects >= 20 years of age, having no diagnosis of glucose intolerance or diabetes, hypertension and dyslipidemia were chosen. The patients were divided into four groups according to their BMI and WaC values. Serum visfatin and HOMA-IR levels did not differ among groups. No correlation was detected between serum visfatin levels and obesity and metabolic parameters. In conclusion, we demonstrated that body fat distribution did not affect serum visfatin levels in healthy female subjects. Further studies are needed to clarify the exact factors influencing and determining serum visfatin levels and its clinical reflections.en_US
dc.identifier.citationErsoy, C. vd. (2010). "Body fat distribution has no effect on serum visfatin levels in healthy female subjects". Cytokine, 49(3), 275-278.en_US
dc.identifier.endpage278tr_TR
dc.identifier.issn1043-4666
dc.identifier.issue3tr_TR
dc.identifier.pubmed20045351tr_TR
dc.identifier.scopus2-s2.0-75449085490tr_TR
dc.identifier.startpage275tr_TR
dc.identifier.urihttps://doi.org/10.1016/j.cyto.2009.11.011
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S1043466609008722
dc.identifier.urihttp://hdl.handle.net/11452/26058
dc.identifier.volume49tr_TR
dc.identifier.wos000275353400007tr_TR
dc.indexed.pubmedPubMeden_US
dc.indexed.scopusScopusen_US
dc.indexed.wosSCIEen_US
dc.language.isoenen_US
dc.publisherAcademic Press - Elsevier Scienceen_US
dc.relation.journalCytokineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectGeneral obesityen_US
dc.subjectVisceral obesityen_US
dc.subjectVisfatinen_US
dc.subjectType-2-diabetes-mellitusen_US
dc.subjectColony-enhancing factoren_US
dc.subjectInsulin-resistanceen_US
dc.subjectViscelar faten_US
dc.subjectMetabolic syndromeen_US
dc.subjectPlasmaen_US
dc.subjectCholesterolen_US
dc.subjectOverweighten_US
dc.subjectGlucoseen_US
dc.subjectProteinen_US
dc.subjectBiochemistry & molecular biologyen_US
dc.subjectCell biologyen_US
dc.subjectImmunologyen_US
dc.subjectRodentiaen_US
dc.subject.emtreeNicotinamide phosphoribosyltransferaseen_US
dc.subject.emtreeAdulten_US
dc.subject.emtreeArticleen_US
dc.subject.emtreeBody fat distributionen_US
dc.subject.emtreeBody massen_US
dc.subject.emtreeControlled studyen_US
dc.subject.emtreeCorrelational studyen_US
dc.subject.emtreeEnzyme blood levelen_US
dc.subject.emtreeFemaleen_US
dc.subject.emtreeHumanen_US
dc.subject.emtreeHuman experimenten_US
dc.subject.emtreeInsulin resistanceen_US
dc.subject.emtreeMetabolic parametersen_US
dc.subject.emtreeNormal humanen_US
dc.subject.emtreeObesityen_US
dc.subject.emtreePatient assessmenten_US
dc.subject.emtreePatient identificationen_US
dc.subject.emtreePriority journalen_US
dc.subject.emtreeWaist circumferenceen_US
dc.subject.meshAdulten_US
dc.subject.meshBlood glucoseen_US
dc.subject.meshBody fat distributionen_US
dc.subject.meshBody mass indexen_US
dc.subject.meshCross-sectional studiesen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshInsulinen_US
dc.subject.meshInsulin resistanceen_US
dc.subject.meshIntra-abdominal faten_US
dc.subject.meshMiddle ageden_US
dc.subject.meshNicotinamide phosphoribosyltransferaseen_US
dc.subject.meshObesityen_US
dc.subject.meshProspective studiesen_US
dc.subject.meshWaist circumferenceen_US
dc.subject.scopusNicotinamide Phosphoribosyltransferase; Nicotinamide-Beta-Riboside; Niacinamideen_US
dc.subject.wosBiochemistry & molecular biologyen_US
dc.subject.wosCell biologyen_US
dc.subject.wosImmunologyen_US
dc.titleBody fat distribution has no effect on serum visfatin levels in healthy female subjectsen_US
dc.typeArticle
dc.wos.quartileQ2en_US

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