Impaired left ventricular systolic and diastolic functions in patients with early grade pulmonary sarcoidosis

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dc.contributor.buuauthorAydın Kaderli, Aysel
dc.contributor.buuauthorGüllülü, Sümeyye
dc.contributor.buuauthorCoşkun, Funda
dc.contributor.buuauthorYılmaz, Dilber Durmaz
dc.contributor.buuauthorUzaslan, Esra Kunt
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Kardiyoloji Anabilim Dalı.tr_TR
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Göğüs Hastlaıkları Anabilim Dalı.tr_TR
dc.contributor.orcid0000-0003-3604-8826tr_TR
dc.contributor.researcheridAAD-1271-2019tr_TR
dc.contributor.scopusid7801322152tr_TR
dc.contributor.scopusid57204660708tr_TR
dc.contributor.scopusid21734137500tr_TR
dc.contributor.scopusid36246929800tr_TR
dc.contributor.scopusid8761653500tr_TR
dc.date.accessioned2022-02-09T08:16:09Z
dc.date.available2022-02-09T08:16:09Z
dc.date.issued2010-12
dc.description.abstractCardiac sarcoidosis is symptomatic in only 5% of patients, and it is an independent predictor of mortality and carries a very poor prognosis. In our study, we aimed to assess left ventricle (LV) systolic and diastolic functions with tissue Doppler imaging (TDI) in patients with early grade pulmonary sarcoidosis. The study population included 55 patients with Grade I-II sarcoidosis (41 females, 14 males, mean age: 47.9 +/- 10.1) and 22 healthy subjects. LV lateral and septal wall early myocardial peak velocity (E-m), late myocardial peak velocity (A(m)), E-m to A(m) ratio, myocardial relaxation time (RTm), myocardial systolic wave (S-m) velocity, isovolumic acceleration (IVA), myocardial pre-contraction time (PCTm), contraction time (CTm), and the PCTm to CTm ratio were measured. No statistically significant difference was detected between the groups according to age, gender, body mass index, systolic and diastolic blood pressure, or heart rate. LV systolic parameters, LV septal, and lateral wall IVA, were significantly lower, and the PCTm to CTm ratio (P = 0.026) was higher at the septal annulus as compared with control group. E-m, a LV diastolic parameter, was significantly lower at the septal annulus. Cardiac sarcoid involvement is not rare and is treatable. It should be identified at an early stage. TDI, especially IVA, may be a suitable tool for the early detection of subclinical LV sarcoid involvement.en_US
dc.identifier.citationKaderli, A. A. vd. (2010). "Impaired left ventricular systolic and diastolic functions in patients with early grade pulmonary sarcoidosis". European Journal of Echocardiography, 11(10), 809-813.en_US
dc.identifier.endpage813tr_TR
dc.identifier.issn1525-2167
dc.identifier.issn1532-2114
dc.identifier.issue10tr_TR
dc.identifier.pubmed20513700tr_TR
dc.identifier.scopus2-s2.0-78649350500tr_TR
dc.identifier.startpage809tr_TR
dc.identifier.urihttps://doi.org/10.1093/ejechocard/jeq070
dc.identifier.urihttps://pubmed.ncbi.nlm.nih.gov/20513700/
dc.identifier.urihttp://hdl.handle.net/11452/24387
dc.identifier.volume11tr_TR
dc.identifier.wos000284431800010tr_TR
dc.indexed.pubmedPubmeden_US
dc.indexed.scopusScopusen_US
dc.indexed.wosSCIEen_US
dc.language.isoenen_US
dc.publisherOxford University Pressen_US
dc.relation.journalEuropean Journal of Echocardiographyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectSarcoidosisen_US
dc.subjectEchocardiographyen_US
dc.subjectTissue doppler imagingen_US
dc.subjectIsovolumic accelerationen_US
dc.subjectTissue doppler-echocardiographyen_US
dc.subjectCardiac sarcoidosisen_US
dc.subjectHearten_US
dc.subjectLongen_US
dc.subjectCardiovascular system & cardiologyen_US
dc.subject.emtreeAdulten_US
dc.subject.emtreeArticleen_US
dc.subject.emtreeBody massen_US
dc.subject.emtreeControlled studyen_US
dc.subject.emtreeDiastolic blood pressureen_US
dc.subject.emtreeEchocardiographyen_US
dc.subject.emtreeFemaleen_US
dc.subject.emtreeHeart contractionen_US
dc.subject.emtreeHeart left ventricleen_US
dc.subject.emtreeHumanen_US
dc.subject.emtreeLung sarcoidosisen_US
dc.subject.emtreeMajor clinical studyen_US
dc.subject.emtreeMaleen_US
dc.subject.emtreePriority journalen_US
dc.subject.emtreeSex differenceen_US
dc.subject.emtreeSystolic blood pressureen_US
dc.subject.meshCase-control studiesen_US
dc.subject.meshDiastoleen_US
dc.subject.meshEchocardiography, doppler, pulseden_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle ageden_US
dc.subject.meshSarcoidosis, pulmonaryen_US
dc.subject.meshStatistics, nonparametricen_US
dc.subject.meshSystoleen_US
dc.subject.meshVentricular dysfunction, leften_US
dc.subject.scopusSarcoidosis; Fluorodeoxyglucose F 18; Heart Ventricle Tachycardiaen_US
dc.subject.wosCardiac & cardiovascular systemsen_US
dc.titleImpaired left ventricular systolic and diastolic functions in patients with early grade pulmonary sarcoidosisen_US
dc.typeArticle
dc.wos.quartileQ2en_US

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