An outbreak of oropharyngeal tularaemia linked to natural spring water
dc.contributor.author | Wilke, Ayşe | |
dc.contributor.author | Meriç, Meliha | |
dc.contributor.author | Grunow, Roland | |
dc.contributor.author | Sayan, Murat | |
dc.contributor.author | Finke, Ernst-Jurgen | |
dc.contributor.author | Splettstoesser, W. | |
dc.contributor.author | Seibold, Erik | |
dc.contributor.author | Erdoğan, Sarper | |
dc.contributor.author | Ergönül, Önder | |
dc.contributor.author | Yumuk, Zeki | |
dc.contributor.buuauthor | Gedikoğlu, Suna | |
dc.contributor.department | Uludağ Üniversitesi/Tıp Fakültesi/Mikrobiyoloji Anabilim Dalı. | tr_TR |
dc.contributor.scopusid | 6603407548 | tr_TR |
dc.date.accessioned | 2022-04-21T13:17:30Z | |
dc.date.available | 2022-04-21T13:17:30Z | |
dc.date.issued | 2009-01 | |
dc.description.abstract | A tularaemia outbreak was investigated involving 188 suspected cases in the Kocaeli region of Turkey between December 2004 and April 2005. A case-control study comprising 135 laboratory-confirmed cases and 55 controls was undertaken to identify risk factors for the development of the outbreak and to evaluate laboratory diagnostic methods. Tularaemia was confirmed by a microagglutination test (MAT) titre of >= 1 :160 in 90 of the patients. In MAT-negative sera, 23/44 (52 %) were positive by ELISA with Francisella tularensis LPS and 1/9 (111 %) by Western blotting with this antigen. A species-specific PCR was positive in 16/25 (64 %) throat swabs and 8/13 (62 %) lymph node aspirates. Multivariate analysis showed that drinking natural spring water was the leading risk factor for the development of tularaemia (P=0.0001, odds ratio 0.165, 95 % CI 0.790-0.346). The outbreak ceased after abandonment of the suspected natural water springs. | en_US |
dc.identifier.citation | Wilke, A. vd. (2009). "An outbreak of oropharyngeal tularaemia linked to natural spring water". Journal of Medical Microbiology, 58(1), 112-116. | en_US |
dc.identifier.endpage | 116 | tr_TR |
dc.identifier.issn | 0022-2615 | |
dc.identifier.issue | 1 | tr_TR |
dc.identifier.pubmed | 19074661 | tr_TR |
dc.identifier.scopus | 2-s2.0-58149522614 | tr_TR |
dc.identifier.startpage | 112 | tr_TR |
dc.identifier.uri | https://doi.org/10.1099/jmm.0.002279-0 | |
dc.identifier.uri | https://www.microbiologyresearch.org/content/journal/jmm/10.1099/jmm.0.002279-0 | |
dc.identifier.uri | http://hdl.handle.net/11452/25973 | |
dc.identifier.volume | 58 | tr_TR |
dc.identifier.wos | 000262314400014 | tr_TR |
dc.indexed.pubmed | PubMed | en_US |
dc.indexed.scopus | Scopus | en_US |
dc.indexed.wos | SCIE | en_US |
dc.language.iso | en | en_US |
dc.publisher | Microbiology | en_US |
dc.relation.collaboration | Yurt içi | tr_TR |
dc.relation.collaboration | Yurt dışı | tr_TR |
dc.relation.journal | Journal of Medical Microbiology | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi | tr_TR |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | MAT | en_US |
dc.subject | Microagglutination test | en_US |
dc.subject | Turkey | en_US |
dc.subject | Microbiology | en_US |
dc.subject.emtree | Antigen | en_US |
dc.subject.emtree | Ceftriaxone | en_US |
dc.subject.emtree | Drinking water | en_US |
dc.subject.emtree | Lipopolysaccharide | en_US |
dc.subject.emtree | Macrolide | en_US |
dc.subject.emtree | Penicillin G | en_US |
dc.subject.emtree | Adult | en_US |
dc.subject.emtree | Agglutination test | en_US |
dc.subject.emtree | Antibody titer | en_US |
dc.subject.emtree | Article | en_US |
dc.subject.emtree | Case control study | en_US |
dc.subject.emtree | Confidence interval | en_US |
dc.subject.emtree | Controlled study | en_US |
dc.subject.emtree | Differential diagnosis | en_US |
dc.subject.emtree | Disease course | en_US |
dc.subject.emtree | Enzyme linked immunosorbent assay | en_US |
dc.subject.emtree | Epidemic | en_US |
dc.subject.emtree | Female | en_US |
dc.subject.emtree | Francisella tularensis | en_US |
dc.subject.emtree | Human | en_US |
dc.subject.emtree | Infection risk | en_US |
dc.subject.emtree | Laboratory diagnosis | en_US |
dc.subject.emtree | Lymph node biopsy | en_US |
dc.subject.emtree | Lymphadenitis | en_US |
dc.subject.emtree | Major clinical study | en_US |
dc.subject.emtree | Male | en_US |
dc.subject.emtree | Multivariate analysis | en_US |
dc.subject.emtree | Oropharyngeal tularemia | en_US |
dc.subject.emtree | Polymerase chain reaction | en_US |
dc.subject.emtree | Priority journal | en_US |
dc.subject.emtree | Species difference | en_US |
dc.subject.emtree | Spring | en_US |
dc.subject.emtree | Statistical significance | en_US |
dc.subject.emtree | Throat culture | en_US |
dc.subject.emtree | Tonsillitis | en_US |
dc.subject.emtree | Tularemia | en_US |
dc.subject.emtree | Turkey (republic) | en_US |
dc.subject.emtree | Water analysis | en_US |
dc.subject.emtree | Western blotting | en_US |
dc.subject.mesh | Adult | en_US |
dc.subject.mesh | Anti-bacterial agents | en_US |
dc.subject.mesh | Case-control studies | en_US |
dc.subject.mesh | Disease outbreaks | en_US |
dc.subject.mesh | Female | en_US |
dc.subject.mesh | Humans | en_US |
dc.subject.mesh | Male | en_US |
dc.subject.mesh | Middle aged | en_US |
dc.subject.mesh | Oropharynx | en_US |
dc.subject.mesh | Tularemia | en_US |
dc.subject.mesh | Turkey | en_US |
dc.subject.mesh | Water microbiology | en_US |
dc.subject.scopus | Francisella Tularensis; Tularemia; Animals | en_US |
dc.subject.wos | Microbiology | en_US |
dc.title | An outbreak of oropharyngeal tularaemia linked to natural spring water | en_US |
dc.type | Article | |
dc.wos.quartile | Q3 | en_US |