Regio- and diastereoselective synthesis of (E)-3-(2-aminochromen-4-yl)-6-aryl-substituted fulvenes
Date
2016-05-03
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Walter de Gruyter Gmbh
Abstract
A practical base-catalyzed route was developed for the regio- and diastereoselective synthesis of (E)-3-aminochromene-6-aryl-disubstituted fulvenes in high yields up to 94% starting with the Michael addition of cyclopentadiene to 2-iminochromenes in the key step.
Description
Keywords
Chemistry, Aminochromene, Base catalysis, Cyclopentadiene, Fulvene, Michael addition, Facile synthesis, Michael reaction, Derivatives, 2-amino-4h-chromenes, Cytotoxicity, Inhibitors, Thiourea, Agents, Addition reactions, Catalysis, Olefins, Aminochromene, Base catalysis, Cyclopentadienes, Fulvene, Michael additions, Stereoselectivity, Anticancer drugs
Citation
Koz, G. vd. (2016). "Regio- and diastereoselective synthesis of (E)-3-(2-aminochromen-4-yl)-6-aryl-substituted fulvenes". Zeitschrift fur Naturforschung-Section B Journal of Chemical Sciences, 71(9), 945-951.