Clinical importance of extended-spectrum beta-lactamase (PER-1-type)-producing Acinetobacter spp. and Pseudomonas aeruginosa strains

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dc.contributor.authorVahaboğlu, Haluk
dc.contributor.authorCoşkukan, Figen
dc.contributor.authorTansel, Özlem
dc.contributor.authorÖztürk, Recep
dc.contributor.authorŞahin, Nursu
dc.contributor.authorKöksal, İftihar
dc.contributor.authorKocazeybek, Bekir
dc.contributor.authorTatman, Müşerref Otkun
dc.contributor.authorLeblebicioğlu, Hakan
dc.contributor.authorÖzinel, Mehmet Ali
dc.contributor.authorKorten, Volkan
dc.contributor.authorKocagöz, Sesin
dc.contributor.buuauthorAkalın, Emin Halis
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Anabilim Dalı.tr_TR
dc.contributor.researcheridAAU-8952-2020tr_TR
dc.date.accessioned2021-07-01T11:56:09Z
dc.date.available2021-07-01T11:56:09Z
dc.date.issued2001-07
dc.description.abstractRecently, an extended-spectrum beta -lactamase (PER-I) was found to be disseminated among Acinetobacter spp, and Pseudomonas aeruginosa isolates in Turkey. A population-based cohort study was conducted to elucidate predictive mortality factors in patients with nosocomial infections caused by Acinetobacter spp. and P. aeruginosa, with particular reference to PER-1-type extended-spectrum beta -lactamase (ESBL) production. The study group comprised 16 and 21 non-survivors and 82 and 126 survivors in cohorts infected with Acinetobacter and E. aeruginosa, respectively. In the Acinetobacter-infected cohort, nosocomial pneumonia, hypotension and infection with a PER-positive isolate were independent predictors of mortality. In the P. aeruginosa-infected cohort, impaired consciousness, a PER-positive isolate, male sex and (with a negative relative risk) urinary tract infection were independent predictors of death. This study demonstrated the relationship of PER-1-type ESBL-producing Acinetobacter spp. and P. aeruginosa with poor clinical outcome.en_US
dc.identifier.citationVahaboğlu, H. vd. (2001). "Clinical importance of extended-spectrum beta-lactamase (PER-1-type)-producing Acinetobacter spp. and Pseudomonas aeruginosa strains". Journal of Medical Microbiology, 50(7), 642-645.en_US
dc.identifier.endpage645tr_TR
dc.identifier.issn0022-2615
dc.identifier.issue7tr_TR
dc.identifier.pubmed11444775tr_TR
dc.identifier.scopus2-s2.0-0034954085tr_TR
dc.identifier.startpage642tr_TR
dc.identifier.urihttps://doi.org/10.1099/0022-1317-50-7-642
dc.identifier.urihttps://www.microbiologyresearch.org/content/journal/jmm/10.1099/0022-1317-50-7-642
dc.identifier.urihttp://hdl.handle.net/11452/20961
dc.identifier.volume50tr_TR
dc.identifier.wos000169534300010tr_TR
dc.indexed.pubmedPubmeden_US
dc.indexed.scopusScopusen_US
dc.indexed.wosSCIEen_US
dc.language.isoenen_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.collaborationYurtiçitr_TR
dc.relation.journalJournal of Medicine Microbiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectMicrobiologyen_US
dc.subjectOuter-membraneen_US
dc.subjectResistanceen_US
dc.subjectBaumanniien_US
dc.subjectAcquisitionen_US
dc.subjectPneumoniaen_US
dc.subjectMortalityen_US
dc.subjectOutbreaken_US
dc.subject.wosMicrobiologyen_US
dc.titleClinical importance of extended-spectrum beta-lactamase (PER-1-type)-producing Acinetobacter spp. and Pseudomonas aeruginosa strainsen_US
dc.typeArticle
dc.wos.quartileQ2en_US

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