The effects of human amniotic membrane and periosteal autograft on tendon healing: Experimental study in rabbits
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Date
2010-05
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Sage Publications
Abstract
In this study, the effects of periosteal autograft and human amniotic membrane on tendon healing were compared. Forty-two New Zealand rabbits were divided into three groups. Flexor digitorum fibularis tendons were cut and repaired with a modified Kessler technique and circumferential sutures in all groups. Tendon repair alone was carried out in group 1, tendon repair and application of human amniotic membrane was done in group 2 and tendon repair and application of periosteal autograft was done in group 3. Biomechanical and histopathological examinations were done 2 and 6 weeks postoperatively. Biomechanical examination showed that group 3 was the strongest at weeks 2 and 6. Adhesion, inflammation and new bone formation showed no difference between groups at week 2. However, adhesion formation was found to be less in groups 2 and 3 than group 1 at week 6. The application of periosteal autograft might be useful in repair of tendon injuries.
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Keywords
Flexor tendon injury, Adhesion formation, Periost, Human amniotic membrane, Experiment, Early active mobilization, Flexor tendon, Peritendinous adhesions, Hyaluronic-acid, Restrictive adhesions, Repair, Sheath, Injury, Motion, Model, Orthopedics, Surgery
Citation
Özbölük, S. vd. (2010). "The effects of human amniotic membrane and periosteal autograft on tendon healing: Experimental study in rabbits". Journal of Hand Surgery-European Volume, 35(4), 262-268.