Clinical and epidemiological features of Turkish children with 2009 pandemic influenza A (H1N1) infection: Experience from multiple tertiary paediatric centres in Turkey

Simple item page
dc.contributor.authorÇiftçi, Ergin
dc.contributor.authorTuygun, Nilden
dc.contributor.authorÖzdemir, Halil
dc.contributor.authorTezer, Hasan
dc.contributor.authorŞensoy, Gülnar
dc.contributor.authorDevrim, İlker
dc.contributor.authorDalgıç, Nazan
dc.contributor.authorKara, Ateş
dc.contributor.authorTurgut, Mehmet
dc.contributor.authorTapısız, Anıl
dc.contributor.authorKeser, Melike
dc.contributor.authorBayram, Nuri
dc.contributor.authorKocabaş, Emine
dc.contributor.authorDinleyici, Ener Çağrı
dc.contributor.authorÖzen, Metehan
dc.contributor.authorSoysal, Ahmet
dc.contributor.authorKuyucu, Necdet
dc.contributor.authorTanır, Gönül
dc.contributor.authorÇelikel, Elif
dc.contributor.authorBelet, Nursen
dc.contributor.authorEvren, Gültaç
dc.contributor.authorAytaç, Didem Büyüktaş
dc.contributor.authorCengiz, Ali Bülent
dc.contributor.authorCanoz, Perihan Yasemen
dc.contributor.authorDerinoz, Oksan
dc.contributor.authorİnce, Erdal
dc.contributor.authorHacımustafaoğlu, Mustafa
dc.contributor.authorAnıl, Murat
dc.contributor.authorÖzgür, Özlem
dc.contributor.authorKuzdan, Canan
dc.contributor.authorÖzaydin, Eda
dc.contributor.authorAşılıoğlu, Nazik
dc.contributor.authorDizdarer, Ceyhun
dc.contributor.authorCeyhan, Mehmet
dc.contributor.authorBucak, İbrahim Hakan
dc.contributor.authorKendirli, Tanıl
dc.contributor.authorYakut, Halil İbrahim
dc.contributor.authorFisgin, Tunç
dc.contributor.authorUnal, Nurettin
dc.contributor.authorAltındağ, Hakan
dc.contributor.authorKılınç, Ayse Ayzit
dc.contributor.authorZohre, Seray Umut
dc.contributor.authorElhan, Atilla Halil
dc.contributor.authorDoğru, Ülker
dc.contributor.buuauthorÇelebi, Solmaz
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Çocuk Enfeksiyon Hastalıkları Anabilim Dalı.tr_TR
dc.contributor.scopusid7006095295tr_TR
dc.date.accessioned2022-11-09T06:51:07Z
dc.date.available2022-11-09T06:51:07Z
dc.date.issued2011-12
dc.description.abstractBackground: In April 2009 a novel strain of human influenza A, identified as H1N1 virus, rapidly spread worldwide, and in early June 2009 the World Health Organization raised the pandemic alert level to phase 6. Herein we present the largest series of children who were hospitalized due to pandemic H1N1 infection in Turkey. Methods: We conducted a retrospective multicentre analysis of case records involving children hospitalized with influenza-like illness, in whom 2009 H1N1 influenza was diagnosed by reverse-transcriptase polymerase chain reaction assay, at 17 different tertiary hospitals. Results: A total of 821 children with 2009 pandemic H1N1 were hospitalized. The majority of admitted children (56.9%) were younger than 5 y of age. Three hundred and seventy-six children (45.8%) had 1 or more pre-existing conditions. Respiratory complications including wheezing, pneumonia, pneumothorax, pneumomediastinum, and hypoxemia were seen in 272 (33.2%) children. Ninety of the patients (11.0%) were admitted or transferred to the paediatric intensive care units (PICU) and 52 (6.3%) received mechanical ventilation. Thirty-five children (4.3%) died. The mortality rate did not differ between age groups. Of the patients who died, 25.7% were healthy before the H1N1 virus infection. However, the death rate was significantly higher in patients with malignancy, chronic neurological disease, immunosuppressive therapy, at least 1 pre-existing condition, and respiratory complications. The most common causes of mortality were pneumonia and sepsis. Conclusions: In Turkey, 2009 H1N1 infection caused high mortality and PICU admission due to severe respiratory illness and complications, especially in children with an underlying condition.en_US
dc.identifier.citationÇiftçi, E. vd.(2011). "Clinical and epidemiological features of Turkish children with 2009 pandemic influenza A (H1N1) infection: Experience from multiple tertiary paediatric centres in Turkey".Scandinavian Journal of Infectious Diseases, 43(11-12), 923-929.en_US
dc.identifier.endpage929tr_TR
dc.identifier.issn0036-5548
dc.identifier.issue11-12tr_TR
dc.identifier.pubmed21859378tr_TR
dc.identifier.scopus2-s2.0-80855133378tr_TR
dc.identifier.startpage923tr_TR
dc.identifier.urihttps://doi.org/10.3109/00365548.2011.598872
dc.identifier.urihttps://www.tandfonline.com/doi/full/10.3109/00365548.2011.598872
dc.identifier.urihttp://hdl.handle.net/11452/29436
dc.identifier.volume43tr_TR
dc.identifier.wos000296641500012tr_TR
dc.indexed.pubmedPubMeden_US
dc.indexed.scopusScopusen_US
dc.indexed.wosSCIEen_US
dc.language.isoenen_US
dc.publisherInforma Healthcareen_US
dc.relation.collaborationYurt içitr_TR
dc.relation.collaborationSanayitr_TR
dc.relation.journalScandinavian Journal of Infectious Diseasesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectInfectious diseasesen_US
dc.subjectChildrenen_US
dc.subjectInfluenza Aen_US
dc.subjectH1N1en_US
dc.subjectMortalityen_US
dc.subjectUKen_US
dc.subject.emtreeOseltamiviren_US
dc.subject.emtree2009 H1N1 influenzaen_US
dc.subject.emtreeAbdominal painen_US
dc.subject.emtreeAdolescenten_US
dc.subject.emtreeAdulten_US
dc.subject.emtreeArticleen_US
dc.subject.emtreeArtificial ventilationen_US
dc.subject.emtreeAsthmaen_US
dc.subject.emtreeChilden_US
dc.subject.emtreeChronic lung diseaseen_US
dc.subject.emtreeClinical featureen_US
dc.subject.emtreeCongenital heart diseaseen_US
dc.subject.emtreeConsciousness disorderen_US
dc.subject.emtreeConvulsionen_US
dc.subject.emtreeCoughingen_US
dc.subject.emtreeDehydrationen_US
dc.subject.emtreeDiabetes mellitusen_US
dc.subject.emtreeDiarrheaen_US
dc.subject.emtreeFatigueen_US
dc.subject.emtreeFemaletr_TR
dc.subject.emtreeFeveren_US
dc.subject.emtreeHeadacheen_US
dc.subject.emtreeHumanen_US
dc.subject.emtreeHypoxemiaen_US
dc.subject.emtreeImmune deficiencyen_US
dc.subject.emtreeImmunosuppressive treatmenten_US
dc.subject.emtreeInfanten_US
dc.subject.emtreeLeukocyteen_US
dc.subject.emtreeMajor clinical studyen_US
dc.subject.emtreeMaleen_US
dc.subject.emtreeMedical record reviewen_US
dc.subject.emtreeMortalityen_US
dc.subject.emtreeMyalgiaen_US
dc.subject.emtreeNeoplasmen_US
dc.subject.emtreeNeurologic diseaseen_US
dc.subject.emtreeNewbornen_US
dc.subject.emtreeObesityen_US
dc.subject.emtreeOxygen therapyen_US
dc.subject.emtreePandemicen_US
dc.subject.emtreePharyngitisen_US
dc.subject.emtreePneumomediastinumen_US
dc.subject.emtreePneumoniaen_US
dc.subject.emtreePneumothoraxen_US
dc.subject.emtreePreschool childen_US
dc.subject.emtreeRespiratory distressen_US
dc.subject.emtreeRetrospective studyen_US
dc.subject.emtreeReverse transcription polymerase chain reactionen_US
dc.subject.emtreeRhinorrheaen_US
dc.subject.emtreeSchool childen_US
dc.subject.emtreeSepsisen_US
dc.subject.emtreeSore throaten_US
dc.subject.emtreeThrombocyte counten_US
dc.subject.emtreeTonsillitisen_US
dc.subject.emtreeTurkey (republic)en_US
dc.subject.emtreeVomitingen_US
dc.subject.emtreeWheezingen_US
dc.subject.meshAdolescenten_US
dc.subject.meshChilden_US
dc.subject.meshChild, preschoolen_US
dc.subject.meshFemaleen_US
dc.subject.meshHospitalizationen_US
dc.subject.meshHumansen_US
dc.subject.meshInfanten_US
dc.subject.meshInfant, newbornen_US
dc.subject.meshInfluenza a virus, H1N1 subtypeen_US
dc.subject.meshInfluenza, humanen_US
dc.subject.meshMaleen_US
dc.subject.meshPandemicsen_US
dc.subject.meshRetrospective studiesen_US
dc.subject.meshTurkeyen_US
dc.subject.scopusHuman Influenza; Pandemics; Influenza A Virus (H1n1)en_US
dc.subject.wosInfectious diseasesen_US
dc.titleClinical and epidemiological features of Turkish children with 2009 pandemic influenza A (H1N1) infection: Experience from multiple tertiary paediatric centres in Turkeyen_US
dc.typeArticle
dc.wos.quartileQ3en_US

Files

License bundle
Now showing 1 - 1 of 1
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

Web of Science
PubMed
Scopus