Prevalence and correlates of erectile dysfunction in type 2 diabetes mellitus: A cross-sectional single-center study among Turkish patients

dc.contributor.authorCander, Soner
dc.contributor.authorÇoban, Soner
dc.contributor.authorAltuner, Şakir
dc.contributor.authorÖz Gül, Özen
dc.contributor.authorYetgin, Zeynel Abidin
dc.contributor.authorUçar, Hakan
dc.contributor.buuauthorAkkurt, Ayşen
dc.contributor.buuauthorTuncel, Ercan
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Endokrinoloji ve Metabolizma Anabilim Dalı.tr_TR
dc.contributor.scopusid55576013900tr_TR
dc.contributor.scopusid7006929833tr_TR
dc.date.accessioned2024-02-19T06:57:52Z
dc.date.available2024-02-19T06:57:52Z
dc.date.issued2014-08
dc.description.abstractObjective: The aim of this study was to evaluate prevalence of erectile dysfunction (ED) in patients with type 2 diabetes mellitus (T2DM) in relation to vascular and neurogenic correlates. Methods: A total of 116 males including T2DM patients [n = 68; mean age, 56.7 (5.8) years] and age-matched healthy controls [n = 48; mean age, 57.0 (6.6) years] were included in this cross-sectional single-center study. Data on anthropometrics, blood biochemistry, concomitant hypertension, hyperlipidemia, and coronary artery disease (CAD) were recorded in each subject along with measurement of carotid artery intima media thickness (CIMT) and evaluation of erectile dysfunction (ED) via International Index of Erectile Function (IIEF-5) Questionnaire. A univariate analysis was performed to determine the relationship of cardiovascular risk factors and diabetes-related complications to ED. Results: Patient and control groups were similar in terms of percentage patients with hyperlipidemia (51.5% and 39.6%, respectively) and CAD (33.8% and 22.9%, respectively), whereas concomitant hypertension was more common (P = 0.05) and CIMT values were significantly higher (P = 0.020) in patients with T2DM compared with controls. Polyneuropathy was noted in 46.2% of patients, nephropathy in 30.8%, and retinopathy in 33.8%. ED scores were significantly lower in patients than controls [14.3 (7.3) vs. 18.2 (6.3), P = 0.004] with a significantly higher percentage of patients than controls in the category of severe dysfunction (29.4 vs. 10.4%, P = 0.014). Univariate analysis revealed that diabetic polyneuropathy was the only factor to be associated with higher likelihood (93.3% in the presence and 60.0% in the absence of neuropathy) and severity (43.3% in the presence and 14.3% in the absence of neuropathy) of ED (P = 0.004). Conclusion: Findings from the present cross-sectional single-center study revealed the prevalence of ED to be considerably higher in patients with T2DM than age-matched healthy controls, with identification of diabetic polyneuropathy as the only risk factor associated with higher likelihood and more severe forms of ED.en_US
dc.identifier.citationCander, S. vd. (2014). "Prevalence and correlates of erectile dysfunction in type 2 diabetes mellitus: A cross-sectional single-center study among Turkish patients". Metabolic Syndrome and Related Disorders, 12(6), 324-329.en_US
dc.identifier.doihttps://doi.org/10.1089/met.2013.0150en_US
dc.identifier.eissn1557-8518
dc.identifier.endpage329tr_TR
dc.identifier.issn1540-4196
dc.identifier.issue6tr_TR
dc.identifier.pubmed24666397tr_TR
dc.identifier.scopus2-s2.0-84904793296tr_TR
dc.identifier.startpage324tr_TR
dc.identifier.urihttps://www.liebertpub.com/doi/10.1089/met.2013.0150en_US
dc.identifier.urihttps://hdl.handle.net/11452/39841en_US
dc.identifier.volume12tr_TR
dc.identifier.wos000340196500004tr_TR
dc.indexed.wosSCIEen_US
dc.language.isoenen_US
dc.publisherMary Ann Lieberten_US
dc.relation.collaborationSanayitr_TR
dc.relation.journalMetabolic Syndrome and Related Disordersen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectEndothelial dysfunctionen_US
dc.subjectImpotenceen_US
dc.subjectInternational indexen_US
dc.subjectAssociationen_US
dc.subjectSmooth-muscleen_US
dc.subjectPathophysiologyen_US
dc.subjectMenen_US
dc.subjectRelaxationen_US
dc.subjectResearch & experimental medicineen_US
dc.subject.emtreeAdulten_US
dc.subject.emtreeArticleen_US
dc.subject.emtreeCardiovascular risken_US
dc.subject.emtreeControlled studyen_US
dc.subject.emtreeDiabetic nephropathyen_US
dc.subject.emtreeDiabetic neuropathyen_US
dc.subject.emtreeDiabetic patienten_US
dc.subject.emtreeDiabetic retinopathyen_US
dc.subject.emtreeDisease severityen_US
dc.subject.emtreeErectile dysfunctionen_US
dc.subject.emtreeHigh risk patienten_US
dc.subject.emtreeHumanen_US
dc.subject.emtreeHyperlipidemiaen_US
dc.subject.emtreeHypertensionen_US
dc.subject.emtreeInternational index of erectile functionen_US
dc.subject.emtreeMajor clinical studyen_US
dc.subject.emtreeMaleen_US
dc.subject.emtreeNon insulin dependent diabetes mellitusen_US
dc.subject.emtreePrevalenceen_US
dc.subject.emtreePriority journalen_US
dc.subject.emtreeRisk factoren_US
dc.subject.emtreeTurk (people)en_US
dc.subject.emtreeAgeden_US
dc.subject.emtreeBlooden_US
dc.subject.emtreeComplicationen_US
dc.subject.emtreeCross-sectional studyen_US
dc.subject.emtreeDiabetes complicationsen_US
dc.subject.emtreeDiabetes mellitus, type 2en_US
dc.subject.emtreeErectile dysfunctionen_US
dc.subject.emtreeFemaleen_US
dc.subject.emtreeHeart function testen_US
dc.subject.emtreeMiddle ageden_US
dc.subject.emtreeTurkeyen_US
dc.subject.meshAgeden_US
dc.subject.meshCross-sectional studiesen_US
dc.subject.meshDiabetes complicationsen_US
dc.subject.meshDiabetes mellitus, type 2en_US
dc.subject.meshErectile dysfunctionen_US
dc.subject.meshFemaleen_US
dc.subject.meshHeart function testsen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle ageden_US
dc.subject.meshPrevalenceen_US
dc.subject.meshRisk factorsen_US
dc.subject.meshTurkeyen_US
dc.subject.scopusImpotence; Phosphodiesterase V Inhibitor; Tadalafilen_US
dc.subject.wosMedicine, research & experimentalen_US
dc.titlePrevalence and correlates of erectile dysfunction in type 2 diabetes mellitus: A cross-sectional single-center study among Turkish patientsen_US
dc.typeArticleen_US
dc.wos.quartileQ3 (Medicine, Research & Experimental)en_US

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