Free choline and phospholipid-bound choline concentrations in serum and dialysate during peritoneal dialysis in children and adults

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dc.contributor.buuauthorİlçol, Yeşim Özarda
dc.contributor.buuauthorDönmez, Osman
dc.contributor.buuauthorYavuz, Mahmut
dc.contributor.buuauthorDilek, Kamil
dc.contributor.buuauthorYurtkuran, Mustafa
dc.contributor.buuauthorUlus, İsmail Hakkı
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Nefroloji Anabilim Dalı.tr_TR
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Farmakoloji ve Klinik Farmakoloji Anabilim Dalı.tr_TR
dc.contributor.researcheridAAL-8873-2021tr_TR
dc.contributor.researcheridD-5340-2015tr_TR
dc.contributor.researcheridAAA-8778-2021tr_TR
dc.contributor.scopusid35741320500tr_TR
dc.contributor.scopusid19033971800tr_TR
dc.contributor.scopusid7006244754tr_TR
dc.contributor.scopusid56005080200tr_TR
dc.contributor.scopusid7003389525tr_TR
dc.contributor.scopusid7004271086tr_TR
dc.date.accessioned2021-10-23T08:19:52Z
dc.date.available2021-10-23T08:19:52Z
dc.date.issued2002-07
dc.description.abstractObjectives: This study tested whether continuous ambulatory peritoneal dialysis (CAPD) changes free or phospholipid-bound choline concentrations in serum or peritoneal dialysis fluid of patients with end stage renal disease (ESRD). Design and methods: Serum and dialysate choline and phospholipid-bound choline were measured before, during and after 6 h CAPD. Results: Serum choline concentrations were higher in patients with ESRD compared with age-matched controls. CAPD lowered serum choline concentrations significantly although it did not influence phospholipid-bound choline. Choline accumulated in the dialysate, reaching 28.4 +/- 2.7 muM in children and 18.2 +/- 1.4 muM in adults, during six hours CAPD; phospholipid-bound choline increased to 22.9 +/- 2.5 muM and 10.8 +/- 1.4 muM in children and adults, respectively. The total daily loss of choline into the dialysate was 181 +/- 20 mumoles in children and 260 +/- 18 mumoles in adults. Conclusion: CAPD causes a substantial loss of choline into peritoneal dialysates and reduces serum choline concentrations significantly.en_US
dc.identifier.citationÖzarda, Y. vd. (2002). "Free choline and phospholipid-bound choline concentrations in serum and dialysate during peritoneal dialysis in children and adults". Clinical Biochemistry, 35(4), 307-313.en_US
dc.identifier.endpage313tr_TR
dc.identifier.issn0009-9120
dc.identifier.issue4tr_TR
dc.identifier.pubmed12135694tr_TR
dc.identifier.scopus2-s2.0-0035992614tr_TR
dc.identifier.startpage307tr_TR
dc.identifier.urihttps://doi.org/10.1016/S0009-9120(02)00319-3
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S0009912002003193
dc.identifier.urihttp://hdl.handle.net/11452/22452
dc.identifier.volume35tr_TR
dc.identifier.wos000177355800010tr_TR
dc.indexed.pubmedPubmeden_US
dc.indexed.scopusScopusen_US
dc.indexed.wosSCIEen_US
dc.language.isoenen_US
dc.publisherPergamon-Elsevier Scienceen_US
dc.relation.journalClinical Biochemistryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCholineen_US
dc.subjectPhospholipid-bound cholineen_US
dc.subjectEnd stage renal diseaseen_US
dc.subjectCAPDen_US
dc.subjectPeritoneal dialysisen_US
dc.subjectRat corpus striatumen_US
dc.subjectAcetylcholine-releaseen_US
dc.subjectParenteral-nutritionen_US
dc.subjectTyrosine-Hydroxylaseen_US
dc.subjectPlasma cholineen_US
dc.subjectBrainen_US
dc.subjectMetabolismen_US
dc.subjectDeficiencyen_US
dc.subjectTransporten_US
dc.subjectCytidineen_US
dc.subjectLiveren_US
dc.subjectMedical laboratory technologyen_US
dc.subject.emtreePhospholipiden_US
dc.subject.emtreeCholineen_US
dc.subject.emtreePeritoneal dialysis fluiden_US
dc.subject.emtreePhospholipiden_US
dc.subject.emtreeDialysis fluiden_US
dc.subject.emtreeAdolescenten_US
dc.subject.emtreeAdulten_US
dc.subject.emtreeAgeden_US
dc.subject.emtreeArticleen_US
dc.subject.emtreeBlood levelen_US
dc.subject.emtreeDialysateen_US
dc.subject.emtreeClinical articleen_US
dc.subject.emtreeContinuous ambulatory peritoneal dialysisen_US
dc.subject.emtreeControlled studyen_US
dc.subject.emtreeFemaleen_US
dc.subject.emtreeHemodialysis patienten_US
dc.subject.emtreeHumanen_US
dc.subject.emtreeKidney diseaseen_US
dc.subject.emtreeMaleen_US
dc.subject.emtreePriority journalen_US
dc.subject.emtreeSchool childen_US
dc.subject.emtreeTreatment outcomeen_US
dc.subject.emtreeBlooden_US
dc.subject.emtreeChilden_US
dc.subject.emtreeChronic kidney failureen_US
dc.subject.emtreeColorimetryen_US
dc.subject.emtreeContinuous ambulatory peritoneal dialysisen_US
dc.subject.emtreeMetabolismen_US
dc.subject.emtreeMethodologyen_US
dc.subject.emtreeMiddle ageden_US
dc.subject.emtreeVitamin deficiencyen_US
dc.subject.meshChilden_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshPhospholipidsen_US
dc.subject.meshCholineen_US
dc.subject.meshCholine deficiencyen_US
dc.subject.meshColorimetryen_US
dc.subject.meshDialysis solutionsen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumanen_US
dc.subject.meshKidney failure, chronicen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle ageen_US
dc.subject.meshPeritoneal dialysis, continuous ambulatoryen_US
dc.subject.meshSupport, non-U.S. gov'ten_US
dc.subject.scopusCholine; Dimethylglycine; Betainesen_US
dc.subject.wosMedical laboratory technologyen_US
dc.titleFree choline and phospholipid-bound choline concentrations in serum and dialysate during peritoneal dialysis in children and adultsen_US
dc.typeArticle
dc.wos.quartileQ2en_US

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