Evaluation of the clinical efficacy of subconjunctival injection of clindamycin in the treatment of naturally occurring infectious bovine keratoconjunctivitis

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dc.contributor.buuauthorŞentürk, Sezgin
dc.contributor.buuauthorÇetin, Cengiz
dc.contributor.buuauthorTemizel, Mutlu
dc.contributor.buuauthorÖzel, Ebru
dc.contributor.departmentUludağ Üniversitesi/Veteriner Fakültesi/Dahiliye Anabilim Dalı.tr_TR
dc.contributor.departmentUludağ Üniversitesi/Veteriner Fakültesi/Mikrobiyoloji Bölümü.tr_TR
dc.contributor.orcid0000-0002-2465-9913tr_TR
dc.contributor.researcheridAAH-5069-2021tr_TR
dc.contributor.scopusid56257771200tr_TR
dc.contributor.scopusid16229589200tr_TR
dc.contributor.scopusid7801559387tr_TR
dc.contributor.scopusid6701603232tr_TR
dc.date.accessioned2023-01-20T12:45:59Z
dc.date.available2023-01-20T12:45:59Z
dc.date.issued2007-04-13
dc.description.abstractObjectives To determine the clinical efficacy of subconjunctival injection of clindamycin in the treatment of naturally occurring infectious bovine keratoconjunctivitis (IBK). Animal studied Clinically, out of 81 animals examined, 46 were found to be suffering from IBK of variable severity. The ocular secretions were collected and cultured for Moraxella bovis. The study included 36 Holstein cattle from which M. Bovis was isolated. These animals ranged between 4 and 28 months of age. Procedures The severity of the clinical findings were scored as normal, mild, moderate, and severe. Clindamycin was injected subconjunctivally at a total dose of 150 mg (1 mL), once daily for 3 days to the test group (n = 18); isotonic saline solution (1 mL) was administered to the control group. After treatment, all cattle were re-examined and clinical response was evaluated on days 3, 7 and 15 post-treatment. Results Compared with the control group and prior to treatment, all active lesions such as blepharospasm, epiphora, photophobia, chemosis, corneal edema, and corneal ulceration were generally resolved by day 15 after subconjunctival injection of clindamycin. Severity of IBK lesions increased on days 3 and 7, compared to baseline in the control group administered isotonic saline solution. Conclusions The results of this study suggest that subconjunctival injection of clindamycin is effective in the treatment of naturally occurring infectious bovine keratoconjunctivitis.en_US
dc.identifier.citationŞentürk, S. vd. (2007). "Evaluation of the clinical efficacy of subconjunctival injection of clindamycin in the treatment of naturally occurring infectious bovine keratoconjunctivitis". Veterinary Ophthalmology, 10(3), 186-189.en_US
dc.identifier.endpage189tr_TR
dc.identifier.issn1463-5224
dc.identifier.issn1463-5216
dc.identifier.issue3tr_TR
dc.identifier.pubmed17445081tr_TR
dc.identifier.scopus2-s2.0-34247115116tr_TR
dc.identifier.startpage186tr_TR
dc.identifier.urihttps://doi.org/10.1111/j.1463-5224.2007.00536.x
dc.identifier.urihttps://onlinelibrary.wiley.com/doi/10.1111/j.1463-5224.2007.00536.x
dc.identifier.urihttp://hdl.handle.net/11452/30576
dc.identifier.volume10tr_TR
dc.identifier.wos000245698200010tr_TR
dc.indexed.pubmedPubMeden_US
dc.indexed.scopusScopusen_US
dc.indexed.wosSCIEen_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.journalVeterinary Ophthalmologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCattleen_US
dc.subjectAnimaliaen_US
dc.subjectMoraxella-bovisen_US
dc.subjectVeterinary sciencesen_US
dc.subjectBosen_US
dc.subjectBovinaeen_US
dc.subjectMoraxella bovisen_US
dc.subjectClindamycinen_US
dc.subjectIBKen_US
dc.subjectKeratoconjunctivitisen_US
dc.subjectMornxella bovisen_US
dc.subjectSubconjunctival injectionen_US
dc.subjectCattleen_US
dc.subjectDogsen_US
dc.subjectOxytetracyclineen_US
dc.subjectHydrochlorideen_US
dc.subjectFlorfenicolen_US
dc.subjectPyodermaen_US
dc.subjectVeterinary sciencesen_US
dc.subject.emtreeCattleen_US
dc.subject.emtreeAntiinfective agenten_US
dc.subject.emtreeClindamycinen_US
dc.subject.emtreeAnimalen_US
dc.subject.emtreeAnimal diseaseen_US
dc.subject.emtreeArticleen_US
dc.subject.emtreeCattle diseaseen_US
dc.subject.emtreeInjectionen_US
dc.subject.emtreeMycobacterium bovisen_US
dc.subject.emtreeClinical trialen_US
dc.subject.emtreeConjunctivaen_US
dc.subject.emtreeControlled clinical trialen_US
dc.subject.emtreeControlled studyen_US
dc.subject.emtreeHospitalizationen_US
dc.subject.emtreeKeratoconjunctivitisen_US
dc.subject.emtreeIsolation and purificationen_US
dc.subject.emtreePathologyen_US
dc.subject.emtreeRandomized controlled trialen_US
dc.subject.emtreeTreatment outcomeen_US
dc.subject.meshAnti-bacterial agentsen_US
dc.subject.meshAnimalsen_US
dc.subject.meshCattle diseasesen_US
dc.subject.meshMycobacterium bovisen_US
dc.subject.meshCattleen_US
dc.subject.meshClindamycinen_US
dc.subject.meshSeverity of illness indexen_US
dc.subject.meshConjunctivaen_US
dc.subject.meshKeratoconjunctivitis, Infectiousen_US
dc.subject.meshInjectionsen_US
dc.subject.meshTreatment outcomeen_US
dc.subject.meshTuberculosis, bovineen_US
dc.subject.scopusMoraxella Bovoculi; Keratoconjunctivitis; Moraxella (Moraxella) Bovisen_US
dc.subject.wosVeterinary sciencesen_US
dc.titleEvaluation of the clinical efficacy of subconjunctival injection of clindamycin in the treatment of naturally occurring infectious bovine keratoconjunctivitisen_US
dc.typeArticle
dc.wos.quartileQ2en_US

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