Optimization of ultrasonic-assisted extraction of quercetin and cyanidin from Pyracantha Coccinea and their scavenging effect on free radicals

dc.contributor.buuauthorŞahin, Saliha
dc.contributor.buuauthorAybastier, Önder
dc.contributor.buuauthorDemir, Cevdet
dc.contributor.departmentUludağ Üniversitesi/Fen-Edebiyat Fakültesi/Kimya Bölümü.tr_TR
dc.contributor.orcid0000-0002-0380-1992tr_TR
dc.contributor.orcid0000-0003-1508-0181tr_TR
dc.contributor.orcid0000-0002-9381-0410tr_TR
dc.contributor.researcheridX-4621-2018tr_TR
dc.contributor.researcheridABA-2005-2020tr_TR
dc.contributor.researcheridAAH-2892-2021tr_TR
dc.contributor.researcheridAFR-1890-2022tr_TR
dc.contributor.scopusid15027401600tr_TR
dc.contributor.scopusid35344478800tr_TR
dc.contributor.scopusid7003565902tr_TR
dc.date.accessioned2023-04-05T12:17:42Z
dc.date.available2023-04-05T12:17:42Z
dc.date.issued2015-11-08
dc.description.abstractThe response surface method was used to optimize the quercetin and cyanidin content experimental parameters for the ultrasonic-assisted extraction of phenolics from Pyracantha coccinea. The optimal conditions were an extraction time of 97 and 93 min, ethanol concentration of 71 and 79% (v/v), HCl concentration of 1.55 and 1.52 mol/L, liquid-solid ratio of 12.2 and 12.6 mL/g for determining the quercetin and cyanidin contents, respectively. The predicted quercetin and cyanidin contents were 2.30 and 4.01 mg/g, respectively. The experimental values agreed with those predicted at the 95% confidence level, which indicates the response surface method was suitable for optimizing the ultrasound-assisted extraction of phenolics from P. coccinea. The scavenging effects of cyanidin and quercetin in P. coccinea extract, which extracted at optimum conditions, on free radicals were investigated using the Fenton oxidation. It was also demonstrated that cyanidin had more effective free radical scavenging activity than quercetin. Practical ApplicationsThe phenolic compounds differ in polarity, acidity, number of both hydroxyl groups and aromatic rings, concentration and matrix complexity, specific extractions techniques must be designed and optimized for each phenolic compound. Response surface methods have been used widely to produce and optimize different industrially important biotechnological and biochemical products. A central composite design was used to optimize the parameters for P. coccinea extractions based on the quercetin and cyanidin content. The study results indicate the ultrasonic-assisted extraction is an economical and efficient method for extracting quercetin and cyanidin from P. coccinea. The free radical scavenging effects of the two phenolic compounds investigated in this study. They act as free scavengers and inhibit free radical production. This study indicates P. coccinea can be considered a good source of naturally occurring antioxidant compounds.en_US
dc.identifier.citationŞahin, S. vd. (2016). "Optimization of ultrasonic-assisted extraction of quercetin and cyanidin from Pyracantha Coccinea and their scavenging effect on free radicals". Journal of Food Biochemistry, 40(4), 472-479.en_US
dc.identifier.endpage479tr_TR
dc.identifier.issn0145-8884
dc.identifier.issn1745-4514
dc.identifier.issue4tr_TR
dc.identifier.scopus2-s2.0-84955267353tr_TR
dc.identifier.startpage472tr_TR
dc.identifier.urihttps://doi.org/10.1111/jfbc.12236
dc.identifier.urihttps://onlinelibrary.wiley.com/doi/10.1111/jfbc.12236
dc.identifier.urihttp://hdl.handle.net/11452/32203
dc.identifier.volume40tr_TR
dc.identifier.wos000382572900010tr_TR
dc.indexed.scopusScopusen_US
dc.indexed.wosSCIEen_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.journalJournal of Food Biochemistryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBiochemistry & molecular biologyen_US
dc.subjectFood science & technologyen_US
dc.subjectResponse-surface methodologyen_US
dc.subjectPhenolic-compoundsen_US
dc.subjectMetabolismen_US
dc.subjectFlavonoidsen_US
dc.subjectAbsorptionen_US
dc.subjectPlantsen_US
dc.subjectChlorine compoundsen_US
dc.subjectExtractionen_US
dc.subjectFlavonoidsen_US
dc.subjectOxidationen_US
dc.subjectPhenolsen_US
dc.subjectSurface propertiesen_US
dc.subjectToxic materialsen_US
dc.subjectCentral composite designsen_US
dc.subjectExperimental parametersen_US
dc.subjectFree radical productionsen_US
dc.subjectFree radical scavengingen_US
dc.subjectFree radical scavenging activityen_US
dc.subjectResponse surface methoden_US
dc.subjectUltrasonic-assisted extractionsen_US
dc.subjectUltrasound-assisted extractionen_US
dc.subjectFree radicalsen_US
dc.subject.scopusPyracantha Coccinea; Phosphotransferases; Protein Kinasesen_US
dc.subject.wosBiochemistry & molecular biologyen_US
dc.subject.wosFood science & technologyen_US
dc.titleOptimization of ultrasonic-assisted extraction of quercetin and cyanidin from Pyracantha Coccinea and their scavenging effect on free radicalsen_US
dc.typeArticle
dc.wos.quartileQ4 (Biochemistry & molecular biology)en_US
dc.wos.quartileQ3 (Food science & technology)en_US

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