Serum ürik asit konsantrasyonu ile koroner arter hastalığı risk faktörlerinin ilişkisi
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Date
1997-01-02
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Publisher
Uludağ Üniversitesi
Abstract
Serum ürik asit (ÜA) düzeyi ile koroner arter hastalığı (KAH) riski arasında bağlantı olduğunu ortaya koyan çalışmalar vardır. Bu çalışmada 98 kişide serum ÜA düzeyi ile KAH risk faktörü olan diğer bazı parametrelerin ilişkisi incelendi. Total kolesterol (TK), LDL-K ve ÜA ile vücut kitle indeksi (VKİ). TK. trigliserid (TG) VLDL-K, LDL-K, ve TK HDL-K arasında anlamlı pozitif korelasyon olduğu saptandı. Serum ÜA düzeyi ile HDL-K arasında ise negatif korelasyon olduğu bulundu. Kadınlarda yapılan korelasyon incelemesi sonucunda ÜA ile VKİ. TG. TK, VLDL-K, TK HDL-K arasında istatistiksel olarak anlamlı korelasyonlar bulundu. Erkeklerde ise ÜA ile aynı parametreler arasında bu korelasyonların azaldığı gözlendi. Serum ÜA düzeyinin TK, LDL-K, TG, VLDL-K. TK/HDL-K ve VKİ gibi risk faktörleri ile korelasyon göstermesi, ürik asitin de KAH için bir risk faktörü olduğunu düşündürmektedir.
There are some studies which show the relationship between serum uric acid (UA) level and the risk of coronary artery disease (CAD). In this study, the relationships between serum UA level and same of the CAD risk factors have been investigated in 98 subjects. As a result of the measurements, total cholesterol (TC). LDL-C and UA levels have been found to be higher in males compared to females white HDL-C values are just the opposite. In the subjects, in general, UA has shown significant correlations with body mass index (BMI, TC. Triglyceride (TG). VLDL-C, LDL-C and TC/HDL-C. but a negative correlation wılh HDL-C. In the female group correlations of UA with BML, TG, TC. VLDL-C and TC,-C are significant. However, in the male group, the correlations of UA with fatter parameters are fesser but have continued to exist. In conclusion, it is thought that because serum UA level shows positive correlations with CAD risk factors such as TC, LDL,-C, TG, VLDL-C, TC/HDL-C and BMI, serum uric acid values can also be taken into account as a risk factor for CAD.
There are some studies which show the relationship between serum uric acid (UA) level and the risk of coronary artery disease (CAD). In this study, the relationships between serum UA level and same of the CAD risk factors have been investigated in 98 subjects. As a result of the measurements, total cholesterol (TC). LDL-C and UA levels have been found to be higher in males compared to females white HDL-C values are just the opposite. In the subjects, in general, UA has shown significant correlations with body mass index (BMI, TC. Triglyceride (TG). VLDL-C, LDL-C and TC/HDL-C. but a negative correlation wılh HDL-C. In the female group correlations of UA with BML, TG, TC. VLDL-C and TC,-C are significant. However, in the male group, the correlations of UA with fatter parameters are fesser but have continued to exist. In conclusion, it is thought that because serum UA level shows positive correlations with CAD risk factors such as TC, LDL,-C, TG, VLDL-C, TC/HDL-C and BMI, serum uric acid values can also be taken into account as a risk factor for CAD.
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Keywords
Ürik asit, Koroner arter hastalığı, Uric acid, Coronary artery disease
Citation
Dirican, M. vd. (1996). ''Serum ürik asit konsantrasyonu ile koroner arter hastalığı risk faktörlerinin ilişkisi''. Uludağ Üniversitesi Tıp Fakültesi Dergisi, 23(1-2-3), 67-70.