Identification of BLAD, DUMPS, citrullinamia and factor XI deficiency in Holstein cattle in Turkey
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Date
2010-01
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Academic Journals
Abstract
In this study 170 Holstein cows reared in the Bursa Region of Turkey were screened in order to detect four autosomal recessive genetic diseases, i.e., BLAD, DUMPS, citrullinamia and FXI deficiency by Polymerase Chain Reaction (PCR) based methods. We found that none of the animals were carried BLAD, citrullinamia and DUMPS, but two cows were detected as carriers of FXI deficiency. After the PCR applications, FXI deficiency free individuals produced one bands were length of 244 bp and carriers individuals for FXI deficiency gave two bands length of 244 and 320 bp. The frequency of the FXI mutant allele and the FXI carrier prevalence were 0.06 and 1.17%, respectively. The results of present study showed that, the situation regarding to the investigated recessive disorders of BLAD, DUMPS, Citrullinamia and FXI deficiency seems to be good.
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Keywords
BLAD, DUMPS, Citrullinamia, Factor XI, Leukocyte adhesion deficiency, Uridine monophosphate synthase, Allele frequency estimation, Molecular definition, Friesian cattle, Bovine, Mutation, Carriers, Prevalence, Disease, Veterinary sciences, Animalia, Bos
Citation
Öner, Y. vd. (2010). "Identification of BLAD, DUMPS, citrullinamia and factor XI deficiency in Holstein cattle in Turkey". Asian Journal of Animal and Veterinary Advances, 5(1), 60-65.