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Title: Assessment of depth of myometrial invasion by endometrial carcinoma: comparison of T2-weighted SE and contrast-enhanced dynamic GRE MR imaging
Authors: Uludağ Üniversitesi/Tıp Fakültesi/Radyoloji Anabilim Dalı.
Uludağ Üniversitesi/Tıp Fakültesi/Kadın Hastalıkları Anabilim Dalı.
Uludağ Üniversitesi/Tıp Fakültesi/Patoloji Anabilim Dalı.
Savcı, Gürsel
Özyaman, T.
Tutar, M.
Bilgin, Tufan
Erol, O.
Tuncel, Ercan
Keywords: Radiology, nuclear medicine & medical imaging
Magnetic resonance
Contrast enhancement
Rapid imaging
Comparative studies
Female pelvis
Uterine neoplasms
Issue Date: 1998
Publisher: Springer Verlag
Citation: Savcı, G. vd. (1998). "Assessment of depth of myometrial invasion by endometrial carcinoma: comparison of T2-weighted SE and contrast-enhanced dynamic GRE MR imaging". European Radiology, 8(2), 218-223.
Abstract: A prospective study was undertaken to assess the value of both T2-weighted spin-echo (SE) and contrast-enhanced dynamic gradient-echo (GRE) sequences using MR imaging in differentiating the deep myometrial invasion from lower stages produced by endometrial carcinoma. For the correlation of MR findings with the histopathologic findings, patients who had no myomotrial invasion (stage 1 a) and patients in whom tumors were confined to the superficial myometrium (stage 1 b) at pathologic examination were combined as lower stages. Twenty patients with endometrial carcinoma were studied using both techniques. The absence of any detectable tumor (stage 1 a) or the presence of a tumor confined to inner half of myometrium (stage 1 b) and extention of tumor to the outer half of myometrium (stage 1 c) were used as the diagnostic criteria. In pathologic examination of excised specimens, deep myometrial invasion was detected in 9 of 20 patients. The sensitivity, specificity, accuracy positive predictive values (PPV) and negative predictive values (NPV) of T2-weighted SE in differentiating deep myometrial invasion from combined lower stages were 88, 91, 90, 88, and 91 %, respectively, whereas corresponding values for contrast-enhanced dynamic GRE sequences were 78, 100, 90, 100, and 85 %. Statistical difference between two sequences did not reach a significant level. We conclude that in cases of absence of visible junctional zone with SE sequence, contrast-enhanced dynamic GRE MR imaging may be helpful.
ISSN: 0938-7994
Appears in Collections:Web of Science

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