Publication:
Aspirin resistance in patients presenting to the emergency department

dc.contributor.buuauthorKöse, Ataman
dc.contributor.buuauthorKöksala, Özlem
dc.contributor.buuauthorArmağan, Erol
dc.contributor.buuauthorSığırlı, Deniz
dc.contributor.buuauthorÖzdemir, Fatma
dc.contributor.buuauthorAkköse, Sule
dc.contributor.departmentTıp Fakültesi
dc.contributor.departmentTıp Fakültesi
dc.contributor.departmentBiyoistatistik Bölümü
dc.contributor.departmentAcil Tıp Ana Bilim Dalı
dc.contributor.orcid0000-0003-2271-5659
dc.contributor.researcheridAAM-7896-2020
dc.contributor.researcheridAAK-8332-2020
dc.contributor.researcheridAAA-7472-2021
dc.contributor.researcheridAAH-8846-2021
dc.contributor.researcheridL-7334-2015
dc.contributor.scopusid55792812100
dc.contributor.scopusid55792424600
dc.contributor.scopusid55792577900
dc.contributor.scopusid55792509300
dc.contributor.scopusid57214275466
dc.contributor.scopusid55792876000
dc.date.accessioned2023-05-26T09:14:04Z
dc.date.available2023-05-26T09:14:04Z
dc.date.issued2013
dc.description.abstractIntroduction: The effect of aspirin is not the same for all patients and some patients can be resistant. Few emergency department (ED) studies have prospectively determined the rate of aspirin resistance in patients presenting to the ED and the most of them consider only specific group of patients. We aimed to evaluate the relation between clinical and laboratory parameters with aspirin resistance in patients presenting to the ED Methods: Using the bed-side point-of-care VerifyNow Aspirin assay (Accumetrics, San Diego, Calif), we sought to determine the rate of aspirin resistance in patients presenting to the ED with any complaint. Results: A total of 97 patients were included in this study. Aspirin resistance was found in 29 (29.9%) of them. There were not any significant differences in age, sex, drug usage, platelet count, ECG changes, heart rate, systolic, or diastolic blood pressure measures between the aspirin-resistant and aspirin-sensitive patients. In addition, patients' aspirin sensitivity and aspirin resistance did not differ significantly with regard to clinic results and diagnoses in the ED. However, patients with renal failure had significantly more aspirin resistance than other patients (p=0.007). Besides, the relationship between aspirin intake <30 time, pulse pressure and aspirin resistance were found out significant. Conclusion: To the best of our knowledge, this second current report of aspirin resistance in patients presenting to the ED pointed-out its presence in 29.9% of patients. In aspirin resistance, renal failure, pulse pressure and aspirin intake time were determined as important factors.
dc.identifier.citationKöse, A. vd. (2013). “Aspirin resistance in patients presenting to the emergency department”. Acta Medica Mediterranea, 29(2), 247-253.
dc.identifier.endpage253
dc.identifier.issn0393-6384
dc.identifier.issn2283-9720
dc.identifier.issue2
dc.identifier.scopus2-s2.0-84880127848
dc.identifier.startpage247
dc.identifier.urihttp://hdl.handle.net/11452/32811
dc.identifier.volume29
dc.identifier.wos000337927100019
dc.indexed.wosSCIE
dc.language.isoen
dc.publisherCarbone Editore
dc.relation.journalActa Medica Mediterranea
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectGeneral & internal medicine
dc.subjectEmergency department
dc.subjectAspirin resistance
dc.subjectRenal failure
dc.subjectPulse pressure
dc.subjectAspirin intake time
dc.subjectCoronary
dc.subjectFrequency
dc.subjectNonresponder
dc.subjectPrevalence
dc.subjectDisease
dc.subject.emtreeAcetylsalicylic acid
dc.subject.emtreeAdult
dc.subject.emtreeAged
dc.subject.emtreeAge
dc.subject.emtreeArticle
dc.subject.emtreeCardiovascular disease
dc.subject.emtreeDiastolic blood pressure
dc.subject.emtreeDrug determination
dc.subject.emtreeDrug monitoring
dc.subject.emtreeDrug resistance
dc.subject.emtreeDrug sensitivity
dc.subject.emtreeDrug use
dc.subject.emtreeElectrocardiogram
dc.subject.emtreeEmergency care
dc.subject.emtreeEmergency ward
dc.subject.emtreeFemale
dc.subject.emtreeHeart rate
dc.subject.emtreeHuman
dc.subject.emtreeKidney failure
dc.subject.emtreeMajor clinical study
dc.subject.emtreeMale
dc.subject.emtreeSex difference
dc.subject.emtreeSystolic blood pressure
dc.subject.emtreeThrombocyte count
dc.subject.scopusAspirin; Acetylsalicylic Acid; Blood Clotting Parameters
dc.subject.wosMedicine, general & internal
dc.titleAspirin resistance in patients presenting to the emergency department
dc.typeArticle
dc.wos.quartileQ4
dspace.entity.typePublication
local.contributor.departmentTıp Fakültesi/Acil Tıp Ana Bilim Dalı
local.contributor.departmentTıp Fakültesi/Biyoistatistik Bölümü
local.indexed.atScopus
local.indexed.atWOS

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