The associations between epileptic seizures, EEG and radiologic findings with prognosis in patients with meningioma

Abstract

Objectives: Meningiomas are majorly benign tumours which are most commonly occured in middle- advanced ages with predominance of women and extra- axial localization. In the literature; it was reported that 19- 63% of the patients with meningioma are suffered from epilepsy in the pre-operative period, 35% of them experience the epileptic seizures as the initial symptom.Methods: A total of51 patients with a diagnosis of intracranial meningioma were retrospectively evaluated.Results: A total of 51 patients with a diagnosis of intracranial meningioma were retrospectively evaluated. 39 of the 51 patients were operated, whereas 12 patients were not. 3 of the not-operated patients had partial seizure. 7 (28%) of the 25 patients with both operation and seizure (25/39) were manageable without seizure with monotherapy; while 4 (16%) patients had a 50% reduction in frequency of seizure with monotherapy. 38 (76.9%) of our patients had EEG pathology in pre-operative period.Conclusion: In our study EEG pathology was detected 76.9% of the patients with predominance of meningiomas with convexity localization. In previous studies, it was shown that 40% of the patients had findings consistent with an intracranial lesion in EEG and the EEG abnormality was lateralized towards the lesion side. In conclusion, we aimed to evaluate whether EEG is an accessible, feasible, method for localization and/or lateralization of the lesion and to discuss its importance along neuroimaging techniques in patients with meningioma.