Publication: Thymic tumors and results of radiotherapy
dc.contributor.author | Sarıhan, Süreyya | |
dc.contributor.author | Bayram, Ahmet Sami | |
dc.contributor.author | Gebitekin, Cengiz | |
dc.contributor.author | Yerci, Ömer | |
dc.contributor.author | Sığırlı, Deniz | |
dc.contributor.buuauthor | SARIHAN, SÜREYYA | |
dc.contributor.buuauthor | BAYRAM, AHMET SAMİ | |
dc.contributor.buuauthor | GEBİTEKİN, CENGİZ | |
dc.contributor.buuauthor | YERCİ, ÖMER | |
dc.contributor.buuauthor | SIĞIRLI, DENİZ | |
dc.contributor.department | Uludağ Üniversitesi/Tıp Fakültesi/Radyasyon Onkolojisi Anabilim Dalı. | |
dc.contributor.department | Uludağ Üniversitesi/Tıp Fakültesi/Göğüs Cerrahisi Anabilim Dalı. | |
dc.contributor.department | Uludağ Üniversitesi/Tıp Fakültesi/Patoloji Anabilim Dalı. | |
dc.contributor.department | Uludağ Üniversitesi/Tıp Fakültesi/Biyoistatistik Anabilim Dalı. | |
dc.contributor.orcid | 0000-0003-4816-5798 | |
dc.contributor.orcid | 0000-0003-0684-0900 | |
dc.contributor.researcherid | JCE-0097-2023 | |
dc.contributor.researcherid | ABB-7580-2020 | |
dc.contributor.researcherid | AAH-4970-2021 | |
dc.contributor.researcherid | AAA-7472-2021 | |
dc.contributor.researcherid | AAE-1069-2022 | |
dc.date.accessioned | 2024-09-25T05:44:32Z | |
dc.date.available | 2024-09-25T05:44:32Z | |
dc.date.issued | 2018-03-01 | |
dc.description.abstract | Aim: The aim of this study was to evaluate thymic epithelial tumors (TETs) for treatment outcomes and prognostic factors on survival.Background: TETs are very rare neoplasms and multidisciplinary approach is recommended according to prognostic factors.Materials and methods: Between 1995 and 2013, 31 patients were treated with median 5400 cGy (range: 1620-6596 cGy) radiotherapy (RT). Eleven patients received adjuvant or concurrent chemotherapy. There were 25 thymomas, 4 thymic carcinomas and 2 thymic neuroendocrin carcinomas. According to Masaoka, staging and WHO classification, cases were divided to good (n: 10), moderate (n: 9) and poor (n: 12) prognostic risk groups. Survival was calculated from diagnosis.Results: In January 2016, 22 cases were alive with median 51.5 months (range: 2-170.5) follow-up. Recurrences were observed in 29% of patients in median 29.5 months (range: 6.5-105). Local control, mean overall (OS) and disease-free survival (DFS) rates were 86%, 119 and 116 months, respectively. There was a significant difference for RO vs. R+ resection (81% vs. 43%, p = 0.06, and 69% vs. 46%, p = 0.05), Masaoka stage I-II vs. III-IV (75% vs. 52%, p = 0.001, and 75% vs. 37%, p < 0.001), and also prognostic risk groups (100% vs. 89% vs. 48%, p = 0.003, and 100% vs. 87% vs. 27%, p = 0.004) in terms of 5-year OS and DFS, respectively.Conclusion: In our study, prognostic risk stratification was shown to be a significant predictor of survival. There is a need to investigate subgroups that may or may not benefit from adjuvant RT. (C) 2017 Greater Poland Cancer Centre. Published by Elsevier Sp. z o.o. All rights reserved. | |
dc.identifier.doi | 10.1016/j.rpor.2017.12.002 | |
dc.identifier.endpage | 104 | |
dc.identifier.issn | 1507-1367 | |
dc.identifier.issue | 2 | |
dc.identifier.startpage | 97 | |
dc.identifier.uri | https://doi.org/10.1016/j.rpor.2017.12.002 | |
dc.identifier.uri | https://www.sciencedirect.com/science/article/pii/S1507136717301037?via%3Dihub | |
dc.identifier.uri | https://hdl.handle.net/11452/45173 | |
dc.identifier.volume | 23 | |
dc.identifier.wos | 000427797200005 | |
dc.indexed.wos | WOS.ESCI | |
dc.language.iso | en | |
dc.publisher | Via Medica | |
dc.relation.journal | Reports of Practical Oncology and Radiotherapy | |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi | |
dc.rights | info:eu-repo/semantics/openAccess | |
dc.subject | Epithelial tumors | |
dc.subject | Postoperative radiotherapy | |
dc.subject | Radiation-therapy | |
dc.subject | Surgical resection | |
dc.subject | Staging system | |
dc.subject | Thymoma | |
dc.subject | Classification | |
dc.subject | Complications | |
dc.subject | Irradiation | |
dc.subject | Carcinomas | |
dc.subject | Oncology | |
dc.subject | Radiology, nuclear medicine & medical imaging | |
dc.title | Thymic tumors and results of radiotherapy | |
dc.type | Article | |
dspace.entity.type | Publication | |
relation.isAuthorOfPublication | 07b16629-e65c-40b0-b11d-825ad7943570 | |
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relation.isAuthorOfPublication.latestForDiscovery | 07b16629-e65c-40b0-b11d-825ad7943570 |
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