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Pegylatedd interferon alfa-2b monotherapy and pegylated interferon alfa-2b plus lamivudine combination therapy for patients with hepatitis B virus E antigen-negative chronic hepatitis B

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Kaymakoglu, Sabahattin
Oğuz, Dilek
Gür, Gürden
Gürel, Selim
Tankurt, Ethem
Ersöz, Galip
Özenirler, Seren
Kalaycı, Cem
Poturoğlu, Şule
Çakaloğlu, Yılmaz

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Amer Soc Microbiology

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Forty-eight hepatitis B virus (HBV) E antigen-negative chronic hepatitis B patients received pegylated interferon alfa-2b either alone or with lamivudine for 48 weeks and were followed for an additional 24 weeks. At the end of follow-up, virological response rates (HBV DNA levels of < 400 copies/ml) were similar in the monotherapy (24%) and combination therapy (26%) groups.

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Microbiology, Pharmacology & pharmacy

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