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Childhood acute lymphoblastic leukemia with near-tetraplody and t(12; 21) (p13;q22) translocation: A case report

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dc.contributor.buuauthorKarkucak, Mutlu
dc.contributor.buuauthorYakut, Tahsin
dc.contributor.buuauthorBaytan, Birol
dc.contributor.buuauthorGülten, Tuna
dc.contributor.buuauthorGüneş, Adalet Meral
dc.contributor.departmentTıp Fakültesi
dc.contributor.departmentTıp Fakültesi
dc.contributor.departmentTıbbi Genel Ana Bilim Dalı
dc.contributor.departmentPediatrik Hematoloji Ana Bilim Dalı
dc.contributor.scopusid35388323500
dc.contributor.scopusid6602802424
dc.contributor.scopusid6506622162
dc.contributor.scopusid6505944216
dc.contributor.scopusid24072843300
dc.date.accessioned2022-11-07T13:45:48Z
dc.date.available2022-11-07T13:45:48Z
dc.date.issued2011
dc.description.abstractFluroscent in situ hybridization analysis indicated presence of t(12;21)(p13;q22) translocation and near-tetraploidy in a case who 11-year-old boy and diagnosed with B precursor acute lymphoblastic leukemia (ALL). Although, some studies suggest good prognostic effect of translocation t(12;21) (p13;q22), there were very little data regarding the prognostic effect of Near-tetraploidy. Here we discussed the prognostic relevance of both t(12;21)(p13;q22) translocation and near tetraplody in Pre-B ALL.
dc.description.abstractPre- B Akut Lenfoblastik Lösemi tanısı konulan 11 yaşında erkek olguda, Floresans insitu hibridizasyon analizinde t(12;21)(p13;q22) translokasyonu ve near-tetraploidi beraber olduğu gösterilmiştir. Bazı çalışmalarda t(12;21)(p13;q22) trans lokasyonunun iyi prognostik etki oluşturduğu belirtmelerine rağmen near-tetraploidinin prognostik etkisi hakkında çok az bil gi vardır. Burada Pre-B Akut Lenfoblastik Lösemili olguda t(12;21)(p13;q22) translokasyonu ile birlikte near tetraplodi bulgu larının birlikte etkisi tartışılmaktadır.
dc.identifier.citationKarkucak, M. vd. (2011). "Childhood acute lymphoblastic leukemia with near-tetraplody and t(12; 21) (p13;q22) translocation: A case report". UHOD - Uluslararasi Hematoloji-Onkoloji Dergisi, 21(3), 192-195.
dc.identifier.endpage195
dc.identifier.issn1306-133X
dc.identifier.issue3
dc.identifier.scopus2-s2.0-80053646851
dc.identifier.startpage192
dc.identifier.urihttps://doi.org/10.4999/uhod.09122
dc.identifier.urihttp://www.uhod.org/pdf/PDF_479.pdf
dc.identifier.urihttp://hdl.handle.net/11452/29422
dc.identifier.volume21
dc.identifier.wos000295573200011
dc.indexed.scopusScopus
dc.indexed.trdizinTrDizin
dc.indexed.wosSCIE
dc.language.isoen
dc.publisherAkad Doktorlar Yayınevi
dc.relation.journalUHOD - Uluslararası Hematoloji-Onkoloji Dergisi
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectOncology
dc.subjectChildhood acute lymphoblastic leukemia
dc.subjectNear-tetraploidy
dc.subjectT(12;21)
dc.subjectMoleculagenetics
dc.subjectHyperdiploidy
dc.subjectTel-aml1
dc.subjectChildren
dc.subjectÇocukluk çağı akut lenfoblastik lösemi
dc.subjectNear-Tetraplodi, t(12;21)
dc.subject.emtreeAntineoplastic agent EMTREE medical terms
dc.subject.emtreeAcute lymphoblastic leukemia
dc.subject.emtreeArticle
dc.subject.emtreeCase report
dc.subject.emtreeChild
dc.subject.emtreeChildhood leukemia
dc.subject.emtreeChromosome 13p
dc.subject.emtreeChromosome translocation 12
dc.subject.emtreeCytogenetics
dc.subject.emtreeFluorescence in situ hybridization
dc.subject.emtreeFollow up
dc.subject.emtreeHuman
dc.subject.emtreeLaboratory test
dc.subject.emtreeMale
dc.subject.emtreePrognosis
dc.subject.emtreeRelapse
dc.subject.emtreeSchool child
dc.subject.emtreeTetraploidy
dc.subject.emtreeTreatment response
dc.subject.scopusAcute Lymphoblastic Leukemia; Chromosome 21; Pre B Lymphocyte
dc.subject.wosOncology
dc.titleChildhood acute lymphoblastic leukemia with near-tetraplody and t(12; 21) (p13;q22) translocation: A case report
dc.title.alternativet(12;21)(p13;q22) translokasyonu ve Near Tetraplodi bulunan çocukluk çağı akut lenfoblastik lösemili bir olgu sunumu
dc.typeArticle
dc.wos.quartileQ4
dc.wos.quartileQ4
dspace.entity.typePublication
local.contributor.departmentTıp Fakültesi/Tıbbi Genel Ana Bilim Dalı
local.contributor.departmentTıp Fakültesi/Pediatrik Hematoloji Ana Bilim Dalı
local.indexed.atTrDizin
local.indexed.atWOS
local.indexed.atScopus

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