Yayın:
Maspin expression in gastrointestinal stromal tumors

Basit Görünüm
dc.contributor.buuauthorAdım, Şaduman Balaban
dc.contributor.buuauthorFiliz, Gülaydan
dc.contributor.buuauthorKanat, Özkan
dc.contributor.buuauthorYerci, Ömer
dc.contributor.buuauthorÖzgüç, Halil Bülent
dc.contributor.buuauthorAytaç, Berna
dc.contributor.departmentTıp Fakültesi
dc.contributor.departmentTıp Fakültesi
dc.contributor.departmentTıp Fakültesi
dc.contributor.departmentTıbbi Patoloji Ana Bilim Dalı
dc.contributor.departmentTıbbi Onkoloji Ana Bilim Dalı
dc.contributor.departmentGenel Cerrahi Ana Bilim Dalı
dc.contributor.researcheridAAH-9746-2021
dc.contributor.scopusid15730076300
dc.contributor.scopusid6602693514
dc.contributor.scopusid55881548500
dc.contributor.scopusid6603810549
dc.contributor.scopusid6603867989
dc.contributor.scopusid56527372000
dc.date.accessioned2022-06-28T11:31:41Z
dc.date.available2022-06-28T11:31:41Z
dc.date.issued2010-03-26
dc.description.abstractBackground: To investigate the role of maspin expression in the progression of gastrointestinal stromal tumors, and its value as a prognostic indicator. Methods: In the study 54 patients with GIST diagnosis were included in Uludag University of Faculty of Medicine, Department of Pathology between 1997-2007. The expression of maspin in 54 cases of gastrointestinal stromal tumor was detected by immunohistochemistry and compared with the clinicopathologic tumor parameters. Results: The positive expression rates for maspin in the GISTs were 66,6% (36 of 54 cases). Maspin overexpression was detected in 9 of 29 high risk tumors (31%) and was significantly higher in very low/low (78.6%) and intermediate-risk tumors (63.6%) than high-risk tumors. Conclusions: Maspin expression might be an important factor in tumor progression and patient prognosis in GIST. In the future, larger series may be studied to examine the prognostic significance of maspin in GISTs and, of course, maspin expression may be studied in different mesenchymal tumors.
dc.identifier.citationAdım, Ş. B. vd. (2010). "Maspin expression in gastrointestinal stromal tumors". World Journal of Surgical Oncology, 8.
dc.identifier.doi10.1186/1477-7819-8-22
dc.identifier.issn1477-7819
dc.identifier.pubmed20346150
dc.identifier.scopus2-s2.0-77952309178
dc.identifier.urihttps://doi.org/10.1186/1477-7819-8-22
dc.identifier.urihttps://wjso.biomedcentral.com/articles/10.1186/1477-7819-8-22
dc.identifier.urihttp://hdl.handle.net/11452/27440
dc.identifier.volume8
dc.identifier.wos000276760000001
dc.indexed.wosSCIE
dc.language.isoen
dc.publisherBMC
dc.relation.journalWorld Journal of Surgical Oncology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectParadoxical expression
dc.subjectP53 expression
dc.subjectGene
dc.subjectCarcinoma
dc.subjectCancer
dc.subjectAngiogenesis
dc.subjectProgression
dc.subjectMammary
dc.subjectSerpin
dc.subjectCells
dc.subjectOncology
dc.subjectSurgery
dc.subject.emtreeMaspin
dc.subject.emtreeSerine proteinase inhibitor
dc.subject.emtreeSERPIN B5
dc.subject.emtreeSERPIN-B5
dc.subject.emtreeTumor marker
dc.subject.emtreeAcute pancreatitis
dc.subject.emtreeAdolescent
dc.subject.emtreeAdult
dc.subject.emtreeAged
dc.subject.emtreeArticle
dc.subject.emtreeCancer diagnosis
dc.subject.emtreeCancer growth
dc.subject.emtreeCancer localization
dc.subject.emtreeCancer risk
dc.subject.emtreeControlled study
dc.subject.emtreeFemale
dc.subject.emtreeFollow up
dc.subject.emtreeGastrointestinal stromal tumor
dc.subject.emtreeHigh risk patient
dc.subject.emtreeHuman
dc.subject.emtreeHuman cell
dc.subject.emtreeImmunohistochemistry
dc.subject.emtreeMajor clinical study
dc.subject.emtreeMale
dc.subject.emtreeMetastasis
dc.subject.emtreeOverall survival
dc.subject.emtreePrognosis
dc.subject.emtreeProtein expression
dc.subject.emtreeSurvival rate
dc.subject.emtreeTumor growth
dc.subject.emtreeCancer staging
dc.subject.emtreeDisease course
dc.subject.emtreeEnzyme immunoassay
dc.subject.emtreeGastrointestinal stromal tumor
dc.subject.emtreeMetabolism
dc.subject.emtreeMiddle aged
dc.subject.emtreePathology
dc.subject.emtreeRisk factor
dc.subject.meshAdolescent
dc.subject.meshAdult
dc.subject.meshAged
dc.subject.meshDisease progression
dc.subject.meshFemale
dc.subject.meshGastrointestinal stromal tumors
dc.subject.meshHumans
dc.subject.meshImmunoenzyme techniques
dc.subject.meshMale
dc.subject.meshMiddle aged
dc.subject.meshNeoplasm staging
dc.subject.meshPrognosis
dc.subject.meshRisk factors
dc.subject.meshSerpins
dc.subject.meshSurvival rate
dc.subject.meshTumor markers, biological
dc.subject.meshYoung adult
dc.subject.scopusSERPIN-b5; Serine Proteinase Inhibitors; Serpins
dc.subject.wosOncology
dc.subject.wosSurgery
dc.titleMaspin expression in gastrointestinal stromal tumors
dc.typeArticle
dc.wos.quartileQ4 (Oncology)
dc.wos.quartileQ3 (Surgery)
dspace.entity.typePublication
local.contributor.departmentTıp Fakültesi/Tıbbi Patoloji Ana Bilim Dalı
local.contributor.departmentTıp Fakültesi/Tıbbi Onkoloji Ana Bilim Dalı
local.contributor.departmentTıp Fakültesi/Genel Cerrahi Ana Bilim Dalı
local.indexed.atScopus
local.indexed.atWOS

Dosyalar

Orijinal seri

Şimdi gösteriliyor 1 - 1 / 1
Küçük Resim
Ad:
Adım_vd_2010.pdf
Boyut:
1.63 MB
Format:
Adobe Portable Document Format
İndir

Lisanslı seri

Şimdi gösteriliyor 1 - 1 / 1
Placeholder
Ad:
license.txt
Boyut:
1.71 KB
Format:
Item-specific license agreed upon to submission
Açıklama
İndir

Koleksiyonlar

İndeksli Yayınlar / Indexed Publications