Publication: Comparison of intraarticular bupivacaine and levobupivacaine with morphine and epinephrine for knee arthroscopy
Date
2013-06-01
Authors
Authors
Özdemir, Nurdan
Kaya, Fatma Nur
Gurbet, Alp
Yılmazlar, Aysun
Demirağ, Burak
Mandıracı, Bilgen Onbaşı
Journal Title
Journal ISSN
Volume Title
Publisher
Aves
Abstract
Objective: To compare the efficacy of intraarticularly injected bupivacaine with levobupivacaine when administered in combination with morphine and adrenaline for post-operative analgesia and functional recovery after knee surgery.Materials and Methods: Sixty American Society of Anesthesiologists physical status I-II patients were randomized into three groups: Group B was administered 30 mL isobaric 0.5% bupivacaine, 2 mg morphine and 100 mu g adrenaline, Group L was administered 30 mL 0.5% levobupivacaine, 2 mg morphine and 100 mu g adrenaline, and Group C was administered 30 mL 0.9% NaCl solution into the knee joint by the surgeon at the end of surgery. The morphine usage and visual analog pain scores were recorded regularly afterwards. We also recorded the time that elapsed before each patients' first mobilization, positive response to straight leg raising, tolerance to 30-50 degrees knee flexion, recovery of quadriceps reflexes and discharge from the hospital. We also recorded patient and surgeon satisfaction.Results: The pain scale values were lower in Groups B and L than in Group C at 2, 4, 6, 8, 12 and 24 hours post-operatively (all p<0.001). In Groups B and L, the time for first analgesic request was longer (p<0.01), the morphine consumption was lower (p<0.001), and the duration of morphine usage was shorter (p<0.001). The times to positive response to straight leg raising, tolerance to 30-50 degrees knee flexion and the first mobilization were shorter in Groups B and L (p<0.001 for all).Conclusion: After arthroscopic knee surgery, intraarticular levobupivacaine combined with morphine and adrenaline decreases analgesic requirements, shortens the postoperative duration of analgesic use and hastens mobilization as effectively as bupivacaine.
Description
Keywords
Arthroscopic surgery, Bupivacaine, Intraarticular injection, Levobupivacaine, Postoperative pain, General & internal medicine