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New accurate deep learning model for diabetic retinopathy detection utilizing sequential pre-processing and transfer learning

dc.contributor.authorSen, Caner
dc.contributor.authorDoganay, Selim
dc.contributor.authorOzcan, Giyasettin
dc.contributor.buuauthorŞEN, CANER
dc.contributor.buuauthorDOĞANAY, SELİM
dc.contributor.buuauthorÖZCAN, GIYASETTİN
dc.contributor.orcid0000-0001-5405-8214
dc.contributor.orcid0000-0002-1166-5919
dc.contributor.researcheridJCN-7713-2023
dc.contributor.researcheridAAH-6225-2021
dc.contributor.researcheridZ-1130-2018
dc.date.accessioned2025-10-17T11:29:37Z
dc.date.issued2025-05-09
dc.description.abstractThis study considers the detection of Diabetic Retinopathy (DR) using deep learning. DR affects 80% of diabetic patients worldwide and is the second leading cause of blindness. Many studies have shown that early diagnosis and treatment are critical to prevent disease progression. The contribution of this study is the development of an accurate DR detection algorithm and corresponding model, where hemorrhages were brought to a more apparent form by an efficient processing pipeline. To handle limited DR data resources and to make the visibility of bleeding in the eye more apparent, we have developed an efficient deep learning model by combining data augmentation, pre-processing, transfer learning, and adaptation of a compatible CNN. The employed dataset comprises fundus images of individuals, which are categorized into five stages of DR. For evaluation, comprehensive ablation studies are conducted on the model. Next, the developed model is evaluated against state-of-theart algorithms and demonstrates promising results in key metrics. Particularly, the model yields 96.95% accuracy and introduces a false negative rate below 1%. Efficient metrics of the study minimize the risk of missed diagnoses and reduce the likelihood of severe vision loss in diabetic patients. Therefore, our model has the potential to contribute to clinical patient care.
dc.identifier.doi10.1016/j.bspc.2025.108060
dc.identifier.issn1746-8094
dc.identifier.scopus2-s2.0-105004659461
dc.identifier.urihttps://doi.org/10.1016/j.bspc.2025.108060
dc.identifier.urihttps://hdl.handle.net/11452/55702
dc.identifier.volume109
dc.identifier.wos001490799800001
dc.indexed.wosWOS.SCI
dc.language.isoen
dc.publisherElsevier
dc.relation.journalBiomedical signal processing and control
dc.subjectBig data analytics
dc.subjectDiabetic retinopathy
dc.subjectSequential pre-processing
dc.subjectDeep learning
dc.subjectScience & Technology
dc.subjectTechnology
dc.subjectEngineering, Biomedical
dc.subjectEngineering
dc.titleNew accurate deep learning model for diabetic retinopathy detection utilizing sequential pre-processing and transfer learning
dc.typeArticle
dspace.entity.typePublication
local.indexed.atWOS
local.indexed.atScopus
relation.isAuthorOfPublication845d6ea4-ae9c-4697-a1c7-eb783e6f37c3
relation.isAuthorOfPublication1ec74e0d-8a28-42f8-be6a-e8f6dd11e958
relation.isAuthorOfPublicationa91a1293-4e4d-4a70-b56a-1dae0daf40f2
relation.isAuthorOfPublication.latestForDiscovery845d6ea4-ae9c-4697-a1c7-eb783e6f37c3

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