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Effect of benzene on liver functions in rats (Rattus norvegicus)

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dc.contributor.buuauthorDere, Egemen
dc.contributor.buuauthorArı, Ferda
dc.contributor.departmentFen Edebiyat Fakültesi
dc.contributor.departmentBiyoloji Ana Bilim Dalı
dc.contributor.orcid0000-0002-6729-7908
dc.contributor.researcheridAAG-7012-2021
dc.contributor.researcheridAAH-5068-2021
dc.contributor.scopusid6603627015
dc.contributor.scopusid24376085300
dc.date.accessioned2021-12-10T11:48:35Z
dc.date.available2021-12-10T11:48:35Z
dc.date.issued2009-07
dc.description.abstractRats (Rattus norvegicus) were intraperitoneally injected with a 100 mg kg (-aEuro parts per thousand 1) dosage of benzene, a toxic and carcinogenic agent widely used for industrial purposes. Changes in lactate dehydrogenase (LDH), alkaline phosphatase (ALP), alanine amino transferase (ALT), aspartate amino transferase (AST) activities in serum of rats were investigated at 2, 4, 8, 16, 32, and 64 h following injection. Serum physiological was administered to control group. Activities were measured using autoanalyzer. Benzene caused significant activations in LDH, ALP, and AST activities in the serum at some test hours (p < 0.05). When compared with the control groups, although an increase occurred in ALT activity, it was seem that this increase wasn't significant (p > 0.05).
dc.identifier.citationDere, E. ve Arı, F. (2009). "Effect of benzene on liver functions in rats (Rattus norvegicus)". Environmental Monitoring and Assessment, 154(1-4), 23-27.
dc.identifier.doi10.1007/s10661-008-0374-7
dc.identifier.endpage27
dc.identifier.issn0167-6369
dc.identifier.issue1-4
dc.identifier.pubmed18566902
dc.identifier.scopus2-s2.0-67650607731
dc.identifier.startpage23
dc.identifier.urihttps://doi.org/10.1007/s10661-008-0374-7
dc.identifier.urihttps://link.springer.com/article/10.1007%2Fs10661-008-0374-7
dc.identifier.urihttp://hdl.handle.net/11452/23172
dc.identifier.volume154
dc.identifier.wos000267824400003
dc.indexed.wosSCIE
dc.language.isoen
dc.publisherSpringer
dc.relation.journalEnvironmental Monitoring and Assessment
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectAlanine amino transferase
dc.subjectAlkaline phosphatase
dc.subjectAspartate amino transferase
dc.subjectBenzene
dc.subjectLactate dehydrogenase
dc.subjectMicrosomal membrane
dc.subjectHl-60 cells
dc.subjectExposure
dc.subjectTissues
dc.subjectPhosphorothionate
dc.subjectMetabolites
dc.subjectBlood
dc.subjectAcid
dc.subjectEnvironmental sciences & ecology
dc.subjectRattus
dc.subjectRattus norvegicus
dc.subjectAmination
dc.subjectAmines
dc.subjectBenzene
dc.subjectBody fluids
dc.subjectRats
dc.subjectAlanine amino transferase
dc.subjectAlkaline phosphatase
dc.subjectAspartate
dc.subjectAspartate amino transferase
dc.subjectCarcinogenic agents
dc.subjectControl groups
dc.subjectIntraperitoneally
dc.subjectLactate dehydrogenase
dc.subjectEnzymes
dc.subjectBenzene
dc.subjectMeasurement method
dc.subjectPhosphatase
dc.subjectPhysiology
dc.subjectRodent
dc.subjectSerum
dc.subject.emtreeAlanine aminotransferase blood level
dc.subject.emtreeAlkaline phosphatase blood level
dc.subject.emtreeArticle
dc.subject.emtreeAspartate aminotransferase blood level
dc.subject.emtreeAutoanalyzer
dc.subject.emtreeControlled study
dc.subject.emtreeEnzyme activation
dc.subject.emtreeEnzyme activity
dc.subject.emtreeInjection
dc.subject.emtreeLiver function
dc.subject.emtreeNonhuman
dc.subject.emtreeRat
dc.subject.emtreeAlanine aminotransferase
dc.subject.emtreeAlkaline phosphatase
dc.subject.emtreeAspartate aminotransferase
dc.subject.emtreeBenzene
dc.subject.emtreeLactate dehydrogenase
dc.subject.meshAlkaline phosphatase
dc.subject.meshAnimals
dc.subject.meshAspartate aminotransferases
dc.subject.meshBenzene
dc.subject.meshEnvironmental pollutants
dc.subject.meshEnzyme activation
dc.subject.meshL-lactate dehydrogenase
dc.subject.meshLiver
dc.subject.meshRats
dc.subject.meshRats, wistar
dc.subject.scopusS-Phenyl-N-Acetylcysteine; Muconic Acid; Benzene
dc.subject.wosEnvironmental sciences
dc.titleEffect of benzene on liver functions in rats (Rattus norvegicus)
dc.typeArticle
dc.wos.quartileQ3
dspace.entity.typePublication
local.contributor.departmentFen Edebiyat Fakültesi/Biyoloji Ana Bilim Dalı
local.indexed.atScopus
local.indexed.atWOS

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