Publication:
Comparison of the efficacies of topical anaesthetics in the reduction of the pain during peripheral intravenous cannulation: A randomised trial

dc.contributor.buuauthorArmaǧan, Erol
dc.contributor.buuauthorKocabaş, Egemen
dc.contributor.buuauthorKöksal, Özlem
dc.contributor.buuauthorŞimşek, Gözde
dc.contributor.buuauthorBal, Haldun
dc.contributor.departmentTıp Fakültesi
dc.contributor.departmentTıp Fakültesi
dc.contributor.departmentAcil Tıp Ana Bilim Dalı
dc.contributor.departmentKan ve Kan Ürünleri Merkezi
dc.contributor.orcid0000-0003-2271-5659
dc.contributor.researcheridAAH-8846-2021
dc.contributor.researcheridAAK-8332-2020
dc.contributor.scopusid6506464232
dc.contributor.scopusid55317360100
dc.contributor.scopusid23389880200
dc.contributor.scopusid57225727701
dc.contributor.scopusid57198099466
dc.date.accessioned2022-02-15T09:37:44Z
dc.date.available2022-02-15T09:37:44Z
dc.date.issued2012-05
dc.description.abstractObjective: This study aimed to compare the efficacies of two different topical anesthetic agents and placebo in the reduction of the pain observed during intravenous (IV) cannulation. Methods: Study enrolled a total of 129 healthy male donors and IV cannulation was performed to antecubital region. The donors were assigned into three groups. Prilocaine-lidocaine mixture cream (E), lidocaine spray (X) and Placebo cream (P) were given to patients. After the administration the donors were waited for approximately 45 minutes. The pain experienced by the donors after the insertion of 16 gauge cannula in arms was recorded as "pain experienced at minute 0, 5 and 15" on 100 mm visual analog scale (VAS). Results: In the first group, there was no significant difference between mean VAS scores recorded after the administration of prilocainelidocaine mixture cream and lidocaine spray before IV cannulation. Mean VAS value was 9.1 mm with prilocaine-lidocaine mixture cream and 9.3 mm with lidocaine spray. In the second group, we detected significant difference between mean VAS scores recorded after the administration of lidocaine spray and placebo cream. Mean VAS value was 9.8 mm with lidocaine spray and 24.3 mm with placebo (p<0.05). In the third group, we found statistically significant difference between VAS scores recorded after the administration of prilocaine-lidocaine mixture cream and placebo cream. Mean VAS value was 8.8 mm with prilocaine-lidocaine mixture cream and 33.0 mm with placebo cream (p<0.05). Conclusion: Although both agents administrated before IV cannulation were superior to placebo in adult patients in this study, we can state that these drugs were not superior to each other and showed similar efficacy.
dc.identifier.citationArmağan, E. vd. (2012). "Comparison of the efficacies of topical anaesthetics in the reduction of the pain during peripheral intravenous cannulation: A randomised trial". Hong Kong Journal of Emergency Medicine, 19(3), 183-188.
dc.identifier.endpage188
dc.identifier.issn1024-9079
dc.identifier.issue3
dc.identifier.scopus2-s2.0-84864072170
dc.identifier.startpage183
dc.identifier.urihttps://doi.org/10.1177/102490791201900305
dc.identifier.urihttps://journals.sagepub.com/doi/10.1177/102490791201900305
dc.identifier.urihttp://hdl.handle.net/11452/24479
dc.identifier.volume19
dc.identifier.wos000304644000005
dc.indexed.wosSCIE
dc.language.isoen
dc.publisherSage Publications
dc.relation.journalHong Kong Journal of Emergency Medicine
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectEmergency medicine
dc.subjectEfficacy
dc.subjectInfiltration anesthesia
dc.subjectPeripheral catheterization
dc.subjectEmla cream
dc.subjectCatheter insertion
dc.subjectBuffered lidocaine
dc.subjectChildren
dc.subjectVenipuncture
dc.subjectLignocaine
dc.subjectAnalgesia
dc.subjectChloride
dc.subjectSuccess
dc.subjectGel
dc.subject.emtreeEmla
dc.subject.emtreeLidocaine
dc.subject.emtreePlacebo
dc.subject.emtreeAdult
dc.subject.emtreeAnalgesia
dc.subject.emtreeArticle
dc.subject.emtreeCannula
dc.subject.emtreeCannulation
dc.subject.emtreeControlled study
dc.subject.emtreeDrug efficacy
dc.subject.emtreeHuman
dc.subject.emtreeHuman experiment
dc.subject.emtreeMale
dc.subject.emtreeNormal human
dc.subject.emtreePain
dc.subject.emtreePain assessment
dc.subject.emtreeProspective study
dc.subject.emtreeScoring system
dc.subject.emtreeTopical anesthesia
dc.subject.emtreeVisual analog scale
dc.subject.scopusPhlebotomy; Procedural Pain; Lidocaine Plus Prilocaine
dc.subject.wosEmergency medicine
dc.titleComparison of the efficacies of topical anaesthetics in the reduction of the pain during peripheral intravenous cannulation: A randomised trial
dc.typeArticle
dc.wos.quartileQ4
dspace.entity.typePublication
local.contributor.departmentTıp Fakültesi/Acil Tıp Ana Bilim Dalı
local.contributor.departmentTıp Fakültesi/Kan ve Kan Ürünleri Merkezi
local.indexed.atScopus
local.indexed.atWOS

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